Neurodevelopmental outcome at seven years in term, acidotic newborns

Hdl Handle:
http://hdl.handle.net/10147/559035
Title:
Neurodevelopmental outcome at seven years in term, acidotic newborns
Authors:
Diviney, M; Pinnamaneni, R; Murphy, JFA; Lynch, B; Rushe, H; Madigan, C; Geary, M; Foran, A
Publisher:
Irish Medical Journal
Journal:
Irish Medical Journal
Issue Date:
Apr-2015
URI:
http://hdl.handle.net/10147/559035
Abstract:
The objective was to follow up a cohort of acidotic full-term infants with or without hypoxic ischemic encephalopathy (HIE) and determine if at 7 years they displayed any neurodevelopmental delays. Children (n=44) were divided according to those with mild (n=25) or severe (n=19) acidosis and were then further subdivided into those with or without HIE. Participants were assessed using the Wechsler Intelligence Scale for Children (WISC-IVUK) and Achenbach Child Behaviour Checklist (CBCL). No differences in WISC-IVUK scores in children without HIE irrespective of the cord pH values were found. Children with HIE grade I scored significantly higher in perceptual reasoning than those with grade III (p<0.01). CBCL scores revealed no differences between groups. Findings suggest evidence of impairment at school-age that correlates with the degree of encephalopathy. Acidosis without the presence of clinical encephalopathy was associated with normal outcome.
Item Type:
Article
Language:
en
Keywords:
INFANTS; NEURODEVELOPMENTAL DISORDER

Full metadata record

DC FieldValue Language
dc.contributor.authorDiviney, Men
dc.contributor.authorPinnamaneni, Ren
dc.contributor.authorMurphy, JFAen
dc.contributor.authorLynch, Ben
dc.contributor.authorRushe, Hen
dc.contributor.authorMadigan, Cen
dc.contributor.authorGeary, Men
dc.contributor.authorForan, Aen
dc.date.accessioned2015-07-06T13:47:25Zen
dc.date.available2015-07-06T13:47:25Zen
dc.date.issued2015-04en
dc.identifier.urihttp://hdl.handle.net/10147/559035en
dc.description.abstractThe objective was to follow up a cohort of acidotic full-term infants with or without hypoxic ischemic encephalopathy (HIE) and determine if at 7 years they displayed any neurodevelopmental delays. Children (n=44) were divided according to those with mild (n=25) or severe (n=19) acidosis and were then further subdivided into those with or without HIE. Participants were assessed using the Wechsler Intelligence Scale for Children (WISC-IVUK) and Achenbach Child Behaviour Checklist (CBCL). No differences in WISC-IVUK scores in children without HIE irrespective of the cord pH values were found. Children with HIE grade I scored significantly higher in perceptual reasoning than those with grade III (p<0.01). CBCL scores revealed no differences between groups. Findings suggest evidence of impairment at school-age that correlates with the degree of encephalopathy. Acidosis without the presence of clinical encephalopathy was associated with normal outcome.en
dc.language.isoenen
dc.publisherIrish Medical Journalen
dc.subjectINFANTSen
dc.subjectNEURODEVELOPMENTAL DISORDERen
dc.titleNeurodevelopmental outcome at seven years in term, acidotic newbornsen
dc.typeArticleen
dc.identifier.journalIrish Medical Journalen
dc.description.fundingNo fundingen
dc.description.provinceLeinsteren
dc.description.peer-reviewpeer-reviewen
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