Tamoxifen and Potent CYP2D6 Inhibitors: A Potentially Lethal Interaction

Hdl Handle:
http://hdl.handle.net/10147/558639
Title:
Tamoxifen and Potent CYP2D6 Inhibitors: A Potentially Lethal Interaction
Authors:
Battley, JE; O’Connor, M; Barron, TI; O’Reilly, S
Publisher:
Irish Medical Journal
Journal:
Irish Medical Journal
Issue Date:
Jun-2015
URI:
http://hdl.handle.net/10147/558639
Abstract:
Tamoxifen has a well-established role in the management of oestrogen-receptor positive breast cancer halving the 5-year recurrence risk of early stage breast cancer, reducing mortality and controlling metastasis. It is an inactive pro-drug which is activated by the hepatic cytochrome P450 system.
Item Type:
Article
Language:
en
Keywords:
BREAST CANCER; MEDICATION

Full metadata record

DC FieldValue Language
dc.contributor.authorBattley, JEen
dc.contributor.authorO’Connor, Men
dc.contributor.authorBarron, TIen
dc.contributor.authorO’Reilly, Sen
dc.date.accessioned2015-06-29T14:44:26Zen
dc.date.available2015-06-29T14:44:26Zen
dc.date.issued2015-06en
dc.identifier.urihttp://hdl.handle.net/10147/558639en
dc.description.abstractTamoxifen has a well-established role in the management of oestrogen-receptor positive breast cancer halving the 5-year recurrence risk of early stage breast cancer, reducing mortality and controlling metastasis. It is an inactive pro-drug which is activated by the hepatic cytochrome P450 system.en
dc.language.isoenen
dc.publisherIrish Medical Journalen
dc.subjectBREAST CANCERen
dc.subjectMEDICATIONen
dc.titleTamoxifen and Potent CYP2D6 Inhibitors: A Potentially Lethal Interactionen
dc.typeArticleen
dc.identifier.journalIrish Medical Journalen
dc.description.fundingNo fundingen
dc.description.provinceLeinsteren
dc.description.peer-reviewpeer-reviewen
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