Anaesthesia for parturients with severe cystic fibrosis: a case series.

Hdl Handle:
http://hdl.handle.net/10147/336296
Title:
Anaesthesia for parturients with severe cystic fibrosis: a case series.
Authors:
Deighan, M; Ash, S; McMorrow, R
Affiliation:
Department of Anaesthetics, National Maternity Hospital, Dublin, Ireland. Electronic address: maireadeighan@doctors.org.uk.
Citation:
Anaesthesia for parturients with severe cystic fibrosis: a case series. 2014, 23 (1):75-9 Int J Obstet Anesth
Journal:
International journal of obstetric anesthesia
Issue Date:
Feb-2014
URI:
http://hdl.handle.net/10147/336296
DOI:
10.1016/j.ijoa.2013.10.006
PubMed ID:
24361190
Abstract:
Cystic fibrosis affects 1 in 1600-2500 live births and is inherited in an autosomal recessive manner. It primarily involves the respiratory, gastrointestinal and reproductive tracts, with impaired clearance of, and obstruction by, increasingly viscous secretions. Severe respiratory disease, diabetes and gastro-oesophageal reflux may result. Improvements in medical management and survival of cystic fibrosis patients means more are committing to pregnancies. Although guidance for anaesthesia in this patient group is available, management and outcome data associated with more severe cases are sparse. Patients with severe cystic fibrosis require multidisciplinary input and should be managed in a tertiary referral centre. Close monitoring of respiratory function and preoperative optimisation during pregnancy are mandatory. The risk of preterm labour and delivery is increased. Pregnancy and delivery can be managed successfully, even in patients with FEV1 <40% predicted. Neuraxial anaesthesia and analgesia should be the technique of choice for delivery. Postoperative care should be carried out in a critical care setting with the provision of postoperative ventilation if necessary.
Item Type:
Article
Language:
en
MeSH:
Adrenergic alpha-Agonists; Adult; Anesthesia, Epidural; Anesthesia, Obstetrical; Anesthesia, Spinal; Anesthetics, Local; Bupivacaine; Cesarean Section; Cystic Fibrosis; Epinephrine; Fatal Outcome; Female; Follow-Up Studies; Humans; Lidocaine; Pregnancy; Pregnancy Complications; Severity of Illness Index; Young Adult
ISSN:
1532-3374

Full metadata record

DC FieldValue Language
dc.contributor.authorDeighan, Men_GB
dc.contributor.authorAsh, Sen_GB
dc.contributor.authorMcMorrow, Ren_GB
dc.date.accessioned2014-11-27T16:46:44Z-
dc.date.available2014-11-27T16:46:44Z-
dc.date.issued2014-02-
dc.identifier.citationAnaesthesia for parturients with severe cystic fibrosis: a case series. 2014, 23 (1):75-9 Int J Obstet Anesthen_GB
dc.identifier.issn1532-3374-
dc.identifier.pmid24361190-
dc.identifier.doi10.1016/j.ijoa.2013.10.006-
dc.identifier.urihttp://hdl.handle.net/10147/336296-
dc.description.abstractCystic fibrosis affects 1 in 1600-2500 live births and is inherited in an autosomal recessive manner. It primarily involves the respiratory, gastrointestinal and reproductive tracts, with impaired clearance of, and obstruction by, increasingly viscous secretions. Severe respiratory disease, diabetes and gastro-oesophageal reflux may result. Improvements in medical management and survival of cystic fibrosis patients means more are committing to pregnancies. Although guidance for anaesthesia in this patient group is available, management and outcome data associated with more severe cases are sparse. Patients with severe cystic fibrosis require multidisciplinary input and should be managed in a tertiary referral centre. Close monitoring of respiratory function and preoperative optimisation during pregnancy are mandatory. The risk of preterm labour and delivery is increased. Pregnancy and delivery can be managed successfully, even in patients with FEV1 <40% predicted. Neuraxial anaesthesia and analgesia should be the technique of choice for delivery. Postoperative care should be carried out in a critical care setting with the provision of postoperative ventilation if necessary.en_GB
dc.language.isoenen
dc.rightsArchived with thanks to International journal of obstetric anesthesiaen_GB
dc.subject.meshAdrenergic alpha-Agonists-
dc.subject.meshAdult-
dc.subject.meshAnesthesia, Epidural-
dc.subject.meshAnesthesia, Obstetrical-
dc.subject.meshAnesthesia, Spinal-
dc.subject.meshAnesthetics, Local-
dc.subject.meshBupivacaine-
dc.subject.meshCesarean Section-
dc.subject.meshCystic Fibrosis-
dc.subject.meshEpinephrine-
dc.subject.meshFatal Outcome-
dc.subject.meshFemale-
dc.subject.meshFollow-Up Studies-
dc.subject.meshHumans-
dc.subject.meshLidocaine-
dc.subject.meshPregnancy-
dc.subject.meshPregnancy Complications-
dc.subject.meshSeverity of Illness Index-
dc.subject.meshYoung Adult-
dc.titleAnaesthesia for parturients with severe cystic fibrosis: a case series.en_GB
dc.typeArticleen
dc.contributor.departmentDepartment of Anaesthetics, National Maternity Hospital, Dublin, Ireland. Electronic address: maireadeighan@doctors.org.uk.en_GB
dc.identifier.journalInternational journal of obstetric anesthesiaen_GB
dc.description.fundingNo fundingen
dc.description.provinceLeinsteren
dc.description.peer-reviewpeer-reviewen
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