Placental pathology in small for gestational age infants

Hdl Handle:
http://hdl.handle.net/10147/326284
Title:
Placental pathology in small for gestational age infants
Authors:
Thorne, J; Downey, P; Mooney, EE
Citation:
Thorne J, Downey P, Mooney EE. Placental pathology in small for gestational age infants. IMJ 2014 107(8)
Publisher:
Irish Medical Journal
Journal:
Irish Medical Journal
Issue Date:
Sep-2014
URI:
http://hdl.handle.net/10147/326284
Abstract:
Infants with intrauterine growth restriction (IUGR) are at an increased risk of perinatal disease, including death. Many, but not all small for gestational age infants (SGA) have IUGR. Placental disease is an important cause of IUGR, and gross and microscopic examination is critical in explaining such cases. Reports of placentas from infants with a birth weight <2SD from the mean (approx 3rd centile) born between Jan 2004-Dec 2011 were evaluated. The principal pathology was determined in each case. Where two or more pathologic findings were present, they were ranked as principal and co-existing in terms of severity. There were 69,493 deliveries over the study period. 461 SGA cases were identified. No placenta was available in 44 cases, and 21 cases of known anomalies were excluded, leaving a study group of 396 cases. Pathology potentially causing or contributing to SGA and/or IUGR was identified in 84.1% of cases. Significant co-existing pathology was seen in 88 cases (22%). Placental examination provides key information in understanding abnormal fetal growth
Item Type:
Article
Language:
en
Keywords:
CHILDBIRTH; NEONATE

Full metadata record

DC FieldValue Language
dc.contributor.authorThorne, Jen_GB
dc.contributor.authorDowney, Pen_GB
dc.contributor.authorMooney, EEen_GB
dc.date.accessioned2014-09-19T11:55:03Z-
dc.date.available2014-09-19T11:55:03Z-
dc.date.issued2014-09-
dc.identifier.citationThorne J, Downey P, Mooney EE. Placental pathology in small for gestational age infants. IMJ 2014 107(8)en_GB
dc.identifier.urihttp://hdl.handle.net/10147/326284-
dc.description.abstractInfants with intrauterine growth restriction (IUGR) are at an increased risk of perinatal disease, including death. Many, but not all small for gestational age infants (SGA) have IUGR. Placental disease is an important cause of IUGR, and gross and microscopic examination is critical in explaining such cases. Reports of placentas from infants with a birth weight <2SD from the mean (approx 3rd centile) born between Jan 2004-Dec 2011 were evaluated. The principal pathology was determined in each case. Where two or more pathologic findings were present, they were ranked as principal and co-existing in terms of severity. There were 69,493 deliveries over the study period. 461 SGA cases were identified. No placenta was available in 44 cases, and 21 cases of known anomalies were excluded, leaving a study group of 396 cases. Pathology potentially causing or contributing to SGA and/or IUGR was identified in 84.1% of cases. Significant co-existing pathology was seen in 88 cases (22%). Placental examination provides key information in understanding abnormal fetal growthen_GB
dc.language.isoenen
dc.publisherIrish Medical Journalen_GB
dc.subjectCHILDBIRTHen_GB
dc.subjectNEONATEen_GB
dc.titlePlacental pathology in small for gestational age infantsen_GB
dc.typeArticleen
dc.identifier.journalIrish Medical Journalen_GB
dc.description.fundingNo fundingen
dc.description.provinceLeinsteren
dc.description.peer-reviewpeer-reviewen
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