Platelet reactivity changes significantly throughout all trimesters of pregnancy compared with the nonpregnant state: a prospective study.

Hdl Handle:
http://hdl.handle.net/10147/326189
Title:
Platelet reactivity changes significantly throughout all trimesters of pregnancy compared with the nonpregnant state: a prospective study.
Authors:
Burke, N; Flood, K; Murray, A; Cotter, B; Dempsey, M; Fay, L; Dicker, P; Geary, M P; Kenny, D; Malone, F D
Affiliation:
Department of Obstetrics and Gynaecology, Royal College of Surgeons in Ireland, Rotunda Hospital, Dublin, Ireland.
Citation:
Burke N et al. Platelet reactivity changes significantly throughout all trimesters of pregnancy compared with the nonpregnant state: a prospective study. BJOG. 2013, 120 (13):1599-604
Journal:
BJOG : an international journal of obstetrics and gynaecology
Issue Date:
Dec-2013
URI:
http://hdl.handle.net/10147/326189
DOI:
10.1111/1471-0528.12394
PubMed ID:
23924249
Abstract:
Platelets play an important role in the pathophysiology of uteroplacental disease and platelet reactivity may be an important marker of uteroplacental disease activity. However, platelet reactivity has not been evaluated comprehensively in normal pregnancy. We sought to evaluate platelet reactivity using a number of agonists at defined time points in pregnancy using a novel platelet assay and compare these with a nonpregnant cohort.
Item Type:
Article
Language:
en
Keywords:
PREGNANCY
Local subject classification:
BLOOD
MeSH:
Adolescent; Adult; Arachidonic Acid; Collagen; Epinephrine; Female; Humans; Longitudinal Studies; Middle Aged; Platelet Aggregation; Pregnancy; Pregnancy Trimesters; Prospective Studies; Young Adult
ISSN:
1471-0528

Full metadata record

DC FieldValue Language
dc.contributor.authorBurke, Nen_GB
dc.contributor.authorFlood, Ken_GB
dc.contributor.authorMurray, Aen_GB
dc.contributor.authorCotter, Ben_GB
dc.contributor.authorDempsey, Men_GB
dc.contributor.authorFay, Len_GB
dc.contributor.authorDicker, Pen_GB
dc.contributor.authorGeary, M Pen_GB
dc.contributor.authorKenny, Den_GB
dc.contributor.authorMalone, F Den_GB
dc.date.accessioned2014-09-17T09:53:27Z-
dc.date.available2014-09-17T09:53:27Z-
dc.date.issued2013-12-
dc.identifier.citationBurke N et al. Platelet reactivity changes significantly throughout all trimesters of pregnancy compared with the nonpregnant state: a prospective study. BJOG. 2013, 120 (13):1599-604en_GB
dc.identifier.issn1471-0528-
dc.identifier.pmid23924249-
dc.identifier.doi10.1111/1471-0528.12394-
dc.identifier.urihttp://hdl.handle.net/10147/326189-
dc.description.abstractPlatelets play an important role in the pathophysiology of uteroplacental disease and platelet reactivity may be an important marker of uteroplacental disease activity. However, platelet reactivity has not been evaluated comprehensively in normal pregnancy. We sought to evaluate platelet reactivity using a number of agonists at defined time points in pregnancy using a novel platelet assay and compare these with a nonpregnant cohort.en_GB
dc.language.isoenen
dc.rightsArchived with thanks to BJOG : an international journal of obstetrics and gynaecologyen_GB
dc.subjectPREGNANCYen_GB
dc.subject.meshAdolescent-
dc.subject.meshAdult-
dc.subject.meshArachidonic Acid-
dc.subject.meshCollagen-
dc.subject.meshEpinephrine-
dc.subject.meshFemale-
dc.subject.meshHumans-
dc.subject.meshLongitudinal Studies-
dc.subject.meshMiddle Aged-
dc.subject.meshPlatelet Aggregation-
dc.subject.meshPregnancy-
dc.subject.meshPregnancy Trimesters-
dc.subject.meshProspective Studies-
dc.subject.meshYoung Adult-
dc.subject.otherBLOODen_GB
dc.titlePlatelet reactivity changes significantly throughout all trimesters of pregnancy compared with the nonpregnant state: a prospective study.en_GB
dc.typeArticleen
dc.contributor.departmentDepartment of Obstetrics and Gynaecology, Royal College of Surgeons in Ireland, Rotunda Hospital, Dublin, Ireland.en_GB
dc.identifier.journalBJOG : an international journal of obstetrics and gynaecologyen_GB
dc.description.fundingOtheren
dc.description.provinceLeinsteren
dc.description.peer-reviewpeer-reviewen

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