Intra-hepatic haemorrhage and shock during post-natal period, in two brothers with haemophilia

Hdl Handle:
http://hdl.handle.net/10147/326167
Title:
Intra-hepatic haemorrhage and shock during post-natal period, in two brothers with haemophilia
Authors:
Nabialek, T; Pinnamaneni, R; Saleemi, MS; Nolan, B; Corcoran, JD
Citation:
Nabialek T et al. Intra-hepatic haemorrhage and shock during post-natal period, in two brothers with haemophilia. IMJ 2014 107(8)
Publisher:
Irish Medical Journal
Journal:
Irish Medical Journal
Issue Date:
Sep-2014
URI:
http://hdl.handle.net/10147/326167
Abstract:
A boy, born at term by vaginal delivery, developed coagulopathy and hypovolaemic shock at 15 hours. pH was 6.66, lactate 21 mmol/l, haemoglobin 8.9 g/dl, platelets 178x10 9 /l, APTT 245 seconds, PT 21 seconds, fibrinogen 0.9 g/l. He was ventilated and received O-negative blood, plasma, vitamin K, antibiotics and inotropic support. He responded to treatment and was extubated after eight hours. Coagulation normalised but he required further blood and platelet transfusions. He developed abdominal distention with hepatomegaly. Ultrasound images suggested a hepatic tumour with haemorrhage into the tumour and the peritoneal cavity (Figure 1). He required further blood and platelets transfusions. By day thirteen, the ultrasound appearances were consistent with a resolving hematoma. Repeated coagulation screens showed prolonged APTT. Factor VIII level of <0.01 IU/ml confirmed a diagnosis of haemophilia A.
Item Type:
Article
Language:
en
Keywords:
NEONATE; BLOOD AND IMMUNE DISORDER

Full metadata record

DC FieldValue Language
dc.contributor.authorNabialek, Ten_GB
dc.contributor.authorPinnamaneni, Ren_GB
dc.contributor.authorSaleemi, MSen_GB
dc.contributor.authorNolan, Ben_GB
dc.contributor.authorCorcoran, JDen_GB
dc.date.accessioned2014-09-16T11:11:01Z-
dc.date.available2014-09-16T11:11:01Z-
dc.date.issued2014-09-
dc.identifier.citationNabialek T et al. Intra-hepatic haemorrhage and shock during post-natal period, in two brothers with haemophilia. IMJ 2014 107(8)en_GB
dc.identifier.urihttp://hdl.handle.net/10147/326167-
dc.description.abstractA boy, born at term by vaginal delivery, developed coagulopathy and hypovolaemic shock at 15 hours. pH was 6.66, lactate 21 mmol/l, haemoglobin 8.9 g/dl, platelets 178x10 9 /l, APTT 245 seconds, PT 21 seconds, fibrinogen 0.9 g/l. He was ventilated and received O-negative blood, plasma, vitamin K, antibiotics and inotropic support. He responded to treatment and was extubated after eight hours. Coagulation normalised but he required further blood and platelet transfusions. He developed abdominal distention with hepatomegaly. Ultrasound images suggested a hepatic tumour with haemorrhage into the tumour and the peritoneal cavity (Figure 1). He required further blood and platelets transfusions. By day thirteen, the ultrasound appearances were consistent with a resolving hematoma. Repeated coagulation screens showed prolonged APTT. Factor VIII level of <0.01 IU/ml confirmed a diagnosis of haemophilia A.en_GB
dc.language.isoenen
dc.publisherIrish Medical Journalen_GB
dc.subjectNEONATEen_GB
dc.subjectBLOOD AND IMMUNE DISORDERen_GB
dc.titleIntra-hepatic haemorrhage and shock during post-natal period, in two brothers with haemophiliaen_GB
dc.typeArticleen
dc.identifier.journalIrish Medical Journalen_GB
dc.description.fundingNo fundingen
dc.description.provinceLeinsteren
dc.description.peer-reviewpeer-reviewen
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