New targeted molecular therapies for cancer: radiological response in intrathoracic malignancies and cardiopulmonary toxicity: what the radiologist needs to know

Hdl Handle:
http://hdl.handle.net/10147/326116
Title:
New targeted molecular therapies for cancer: radiological response in intrathoracic malignancies and cardiopulmonary toxicity: what the radiologist needs to know
Authors:
Souza, Frederico F; Smith, Andrew; Araujo, Cyrillo; Jagannathan, Jyothi; Johnston, Ciaran; O’Regan, Kevin; Shinagare, Atul; Ramaiya, Nikhil
Citation:
Souza FF et al. New targeted molecular therapies for cancer: radiological response in intrathoracic malignancies and cardiopulmonary toxicity: what the radiologist needs to know. Cancer Imag. 2014 Jul 23;14(1):26
Issue Date:
23-Jul-2014
URI:
http://dx.doi.org/10.1186/1470-7330-14-26; http://hdl.handle.net/10147/326116
Abstract:
Abstract The emergence of new novel therapeutic agents which directly target molecules that are uniquely or abnormally expressed in cancer cells (molecular targeted therapy, MTT) has changed dramatically the treatment of cancer in recent years. The clinical benefit associated with these agents is typically limited to a subset of treated patients, who in many cases are defined by a specific genomic mutations and expression lesion within their tumor cells. All these new therapy modalities represent new challenges to radiologists as their mechanism of action and side effect profiles differ from conventional chemotherapy agents. In this article we will discuss radiological patterns of response to molecular targeted therapies MTT in lung cancer, typical and atypical radiological responses of targeted molecular therapy for other intra thoracic malignancies, cardiopulmonary toxicity and other side effects of molecular targeted therapy MTT in the thorax.
Item Type:
Article
Language:
en
Keywords:
CANCER; THERAPY

Full metadata record

DC FieldValue Language
dc.contributor.authorSouza, Frederico Fen_GB
dc.contributor.authorSmith, Andrewen_GB
dc.contributor.authorAraujo, Cyrilloen_GB
dc.contributor.authorJagannathan, Jyothien_GB
dc.contributor.authorJohnston, Ciaranen_GB
dc.contributor.authorO’Regan, Kevinen_GB
dc.contributor.authorShinagare, Atulen_GB
dc.contributor.authorRamaiya, Nikhilen_GB
dc.date.accessioned2014-09-16T10:45:30Z-
dc.date.available2014-09-16T10:45:30Z-
dc.date.issued2014-07-23-
dc.identifier.citationSouza FF et al. New targeted molecular therapies for cancer: radiological response in intrathoracic malignancies and cardiopulmonary toxicity: what the radiologist needs to know. Cancer Imag. 2014 Jul 23;14(1):26en_GB
dc.identifier.urihttp://dx.doi.org/10.1186/1470-7330-14-26-
dc.identifier.urihttp://hdl.handle.net/10147/326116-
dc.description.abstractAbstract The emergence of new novel therapeutic agents which directly target molecules that are uniquely or abnormally expressed in cancer cells (molecular targeted therapy, MTT) has changed dramatically the treatment of cancer in recent years. The clinical benefit associated with these agents is typically limited to a subset of treated patients, who in many cases are defined by a specific genomic mutations and expression lesion within their tumor cells. All these new therapy modalities represent new challenges to radiologists as their mechanism of action and side effect profiles differ from conventional chemotherapy agents. In this article we will discuss radiological patterns of response to molecular targeted therapies MTT in lung cancer, typical and atypical radiological responses of targeted molecular therapy for other intra thoracic malignancies, cardiopulmonary toxicity and other side effects of molecular targeted therapy MTT in the thorax.-
dc.language.isoenen
dc.subjectCANCERen_GB
dc.subjectTHERAPYen_GB
dc.titleNew targeted molecular therapies for cancer: radiological response in intrathoracic malignancies and cardiopulmonary toxicity: what the radiologist needs to knowen_GB
dc.typeArticleen
dc.language.rfc3066en-
dc.rights.holderFrederico F Souza et al.; licensee BioMed Central Ltd.-
dc.description.statusPeer Reviewed-
dc.date.updated2014-09-08T15:03:53Z-
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