Body composition by computed tomography as a predictor of toxicity in patients with renal cell carcinoma treated with sunitinib.
Authors
Cushen, Samantha JPower, Derek G
Teo, Min Y
Maceneaney, Peter
Maher, Michael M
McDermott, Ray
O'Sullivan, Kathleen
Ryan, Aoife M
Affiliation
*Department of Food & Nutritional Sciences ∥School of Mathematical Science, University College Cork †Department of Medical Oncology, Mercy & Cork University Hospitals §Department of Radiology, Mercy University Hospital, Cork ‡Department Medical Oncology, Adelaide & Meath Hospital incorporating National Children's Hospital, Tallaght, Ireland.Issue Date
2014-04-21Keywords
CANCERDRUG
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Body Composition by Computed Tomography as a Predictor of Toxicity in Patients With Renal Cell Carcinoma Treated With Sunitinib. 2014: Am. J. Clin. Oncol.Journal
American journal of clinical oncologyDOI
10.1097/COC.0000000000000061PubMed ID
24685884Abstract
Sunitinib is a standard first-line option for metastatic renal cell carcinoma (mRCC). Body composition is a prognostic factor in cancer patients and patients with loss of skeletal muscle mass and fat-free mass (FFM) are prone to dose-limiting toxicity (DLT) during targeted drug therapy. We investigated whether body composition by computed tomography predicted DLT from sunitinib in mRCC.Item Type
ArticleLanguage
enISSN
1537-453Xae974a485f413a2113503eed53cd6c53
10.1097/COC.0000000000000061
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