Congenital anomalies and proximity to landfill sites.

Hdl Handle:
http://hdl.handle.net/10147/323814
Title:
Congenital anomalies and proximity to landfill sites.
Authors:
Boyle, E; Johnson, H; Kelly, A; McDonnell, R
Affiliation:
Health Information Unit, Department of Public Health, Eastern Regional Health Authority, Dublin.
Citation:
Boyle E, Johnson H, Kelly A, McDonnell R. Congenital anomalies and proximity to landfill sites. Ir Med J. 2004;97 (1):16-8
Journal:
Irish medical journal
Issue Date:
Jan-2004
URI:
http://hdl.handle.net/10147/323814
PubMed ID:
15055915
Abstract:
The occurrence of congenital anomalies in proximity to municipal landfill sites in the Eastern Region (counties Dublin, Kildare, Wicklow) was examined by small area (district electoral division), distance and clustering tendancies in relation to 83 landfills, five of which were major sites. The study included 2136 cases of congenital anomaly, 37,487 births and 1423 controls between 1986 and 1990. For the more populous areas of the region 50% of the population lived within 2-3 km of a landfill and within 4-5 km for more rural areas. In the area-level analysis, the standardised prevalence ratios, empirical and full Bayesian modelling, and Kulldorff's spatial scan statistic found no association between the residential area of cases and location of landfills. In the case control analysis, the mean distance of cases and controls from the nearest landfill was similar. The odds ratios of cases compared to controls for increasing distances from all landfills and major landfills showed no significant difference from the baseline value of 1. The kernel and K methods showed no tendency of cases to cluster in relationship to landfills. In conclusion, congenital anomalies were not found to occur more commonly in proximity to municipal landfills.
Item Type:
Article
Language:
en
Description:
The occurrence of congenital anomalies in proximity to municipal landfill sites in the Eastern Region (counties Dublin, Kildare, Wicklow) was examined by small area (district electoral division), distance and clustering tendancies in relation to 83 landfills, five of which were major sites. The study included 2136 cases of congenital anomaly, 37,487 births and 1423 controls between 1986 and 1990. For the more populous areas of the region 50% of the population lived within 2-3 km of a landfill and within 4-5 km for more rural areas. In the area-level analysis, the standardised prevalence ratios, empirical and full Bayesian modelling, and Kulldorff's spatial scan statistic found no association between the residential area of cases and location of landfills. In the case control analysis, the mean distance of cases and controls from the nearest landfill was similar. The odds ratios of cases compared to controls for increasing distances from all landfills and major landfills showed no significant difference from the baseline value of 1. The kernel and K methods showed no tendency of cases to cluster in relationship to landfills. In conclusion, congenital anomalies were not found to occur more commonly in proximity to municipal landfills.
Keywords:
ENVIRONMENTAL DETERMINANT
Local subject classification:
BIRTH DEFECTS; PUBLIC HEALTH DEPARTMENT; CONGENITAL ANOMALY; HEALTH IMPROVEMENT
MeSH:
Bayes Theorem; Case-Control Studies; Confidence Intervals; Congenital Abnormalities; Environmental Pollutants; Female; Hazardous Waste; Humans; Incidence; Infant, Newborn; Ireland; Male; Odds Ratio; Risk Assessment; Sex Distribution
ISSN:
0332-3102

Full metadata record

DC FieldValue Language
dc.contributor.authorBoyle, Een_GB
dc.contributor.authorJohnson, Hen_GB
dc.contributor.authorKelly, Aen_GB
dc.contributor.authorMcDonnell, Ren_GB
dc.date.accessioned2014-07-25T11:10:04Zen
dc.date.available2014-07-25T11:10:04Zen
dc.date.issued2004-01en
dc.identifier.citationBoyle E, Johnson H, Kelly A, McDonnell R. Congenital anomalies and proximity to landfill sites. Ir Med J. 2004;97 (1):16-8en_GB
dc.identifier.issn0332-3102en
dc.identifier.pmid15055915en
dc.identifier.urihttp://hdl.handle.net/10147/323814en
dc.descriptionThe occurrence of congenital anomalies in proximity to municipal landfill sites in the Eastern Region (counties Dublin, Kildare, Wicklow) was examined by small area (district electoral division), distance and clustering tendancies in relation to 83 landfills, five of which were major sites. The study included 2136 cases of congenital anomaly, 37,487 births and 1423 controls between 1986 and 1990. For the more populous areas of the region 50% of the population lived within 2-3 km of a landfill and within 4-5 km for more rural areas. In the area-level analysis, the standardised prevalence ratios, empirical and full Bayesian modelling, and Kulldorff's spatial scan statistic found no association between the residential area of cases and location of landfills. In the case control analysis, the mean distance of cases and controls from the nearest landfill was similar. The odds ratios of cases compared to controls for increasing distances from all landfills and major landfills showed no significant difference from the baseline value of 1. The kernel and K methods showed no tendency of cases to cluster in relationship to landfills. In conclusion, congenital anomalies were not found to occur more commonly in proximity to municipal landfills.en_GB
dc.description.abstractThe occurrence of congenital anomalies in proximity to municipal landfill sites in the Eastern Region (counties Dublin, Kildare, Wicklow) was examined by small area (district electoral division), distance and clustering tendancies in relation to 83 landfills, five of which were major sites. The study included 2136 cases of congenital anomaly, 37,487 births and 1423 controls between 1986 and 1990. For the more populous areas of the region 50% of the population lived within 2-3 km of a landfill and within 4-5 km for more rural areas. In the area-level analysis, the standardised prevalence ratios, empirical and full Bayesian modelling, and Kulldorff's spatial scan statistic found no association between the residential area of cases and location of landfills. In the case control analysis, the mean distance of cases and controls from the nearest landfill was similar. The odds ratios of cases compared to controls for increasing distances from all landfills and major landfills showed no significant difference from the baseline value of 1. The kernel and K methods showed no tendency of cases to cluster in relationship to landfills. In conclusion, congenital anomalies were not found to occur more commonly in proximity to municipal landfills.en
dc.language.isoenen
dc.rightsArchived with thanks to Irish medical journalen_GB
dc.subjectENVIRONMENTAL DETERMINANTen_GB
dc.subject.meshBayes Theoremen
dc.subject.meshCase-Control Studiesen
dc.subject.meshConfidence Intervalsen
dc.subject.meshCongenital Abnormalitiesen
dc.subject.meshEnvironmental Pollutantsen
dc.subject.meshFemaleen
dc.subject.meshHazardous Wasteen
dc.subject.meshHumansen
dc.subject.meshIncidenceen
dc.subject.meshInfant, Newbornen
dc.subject.meshIrelanden
dc.subject.meshMaleen
dc.subject.meshOdds Ratioen
dc.subject.meshRisk Assessmenten
dc.subject.meshSex Distributionen
dc.subject.otherBIRTH DEFECTSen_GB
dc.subject.otherPUBLIC HEALTH DEPARTMENTen
dc.subject.otherCONGENITAL ANOMALYen
dc.subject.otherHEALTH IMPROVEMENTen
dc.titleCongenital anomalies and proximity to landfill sites.en_GB
dc.typeArticleen
dc.contributor.departmentHealth Information Unit, Department of Public Health, Eastern Regional Health Authority, Dublin.en_GB
dc.identifier.journalIrish medical journalen_GB

Related articles on PubMed

All Items in Lenus, The Irish Health Repository are protected by copyright, with all rights reserved, unless otherwise indicated.