A diagnostic dilemma: drug-induced aseptic meningitis in a 45-year-old HIV-positive man.
Affiliation
The GUIDE Clinic (Genitourinary and Infectious Disease Department), St James Hospital, Dublin, Ireland.Issue Date
2014-03Keywords
HIV INFECTIONMENINGITIS
MeSH
Anti-Bacterial AgentsAza Compounds
HIV Infections
Humans
Male
Meningitis, Aseptic
Middle Aged
Quinolines
Treatment Outcome
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Rowley D et al. A diagnostic dilemma: drug-induced aseptic meningitis in a 45-year-old HIV-positive man. Int J STD AIDS 2014, 25 (4):309-11Journal
International journal of STD & AIDSDOI
10.1177/0956462413501157PubMed ID
23999938Abstract
We describe a case of aseptic meningitis following the administration of moxifloxacin in a 45-year-old man with human immunodeficiency virus (HIV). At presentation he was receiving tuberculosis treatment on a modified regimen following severe hepatotoxicity; this included moxifloxacin, started 8 days previously. Initial cerebrospinal fluid (CSF) analysis was grossly abnormal. Anti-viral and -bacterial treatments were started. All microbiological tests proved negative and his moxifloxacin was withheld resulting in a complete normalisation of CSF. Drug-induced aseptic meningitis is a diagnosis of exclusion and presents a serious diagnostic dilemma. The decision to withhold medication cannot be taken lightly.Item Type
ArticleLanguage
enISSN
1758-1052ae974a485f413a2113503eed53cd6c53
10.1177/0956462413501157
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