Exploiting biospectroscopy as a novel screening tool for cervical cancer: towards a framework to validate its accuracy in a routine clinical setting.

Hdl Handle:
http://hdl.handle.net/10147/323382
Title:
Exploiting biospectroscopy as a novel screening tool for cervical cancer: towards a framework to validate its accuracy in a routine clinical setting.
Authors:
Purandare, Nikhil C; Trevisan, Júlio; Patel, Imran I; Gajjar, Ketan; Mitchell, Alana L; Theophilou, Georgios; Valasoulis, George; Martin, Mary; von Bünau, Günther; Kyrgiou, Maria; Paraskevaidis, Evangelos; Martin-Hirsch, Pierre L; Prendiville, Walter J; Martin, Francis L
Citation:
Exploiting biospectroscopy as a novel screening tool for cervical cancer: towards a framework to validate its accuracy in a routine clinical setting. 2013, 5 (21):2697-711 Bioanalysis
Journal:
Bioanalysis
Issue Date:
Nov-2013
URI:
http://hdl.handle.net/10147/323382
DOI:
10.4155/bio.13.233
PubMed ID:
24180508
Abstract:
Biospectroscopy is an emerging field that harnesses the platform of physical sciences with computational analysis in order to shed novel insights on biological questions. An area where this approach seems to have potential is in screening or diagnostic clinical settings, where there is an urgent need for new approaches to objectively interrogate large numbers of samples in an objective fashion with acceptable levels of sensitivity and specificity. This review outlines the benefits of biospectroscopy in screening for precancer lesions of the cervix due to its ability to separate different grades of dysplasia. It evaluates the feasibility of introducing this technique into cervical screening programs on the basis of its ability to identify biomarkers of progression within derived spectra ('biochemical‑cell fingerprints').
Item Type:
Article
Language:
en
Keywords:
CERVICAL CANCER
ISSN:
1757-6199

Full metadata record

DC FieldValue Language
dc.contributor.authorPurandare, Nikhil Cen_GB
dc.contributor.authorTrevisan, Júlioen_GB
dc.contributor.authorPatel, Imran Ien_GB
dc.contributor.authorGajjar, Ketanen_GB
dc.contributor.authorMitchell, Alana Len_GB
dc.contributor.authorTheophilou, Georgiosen_GB
dc.contributor.authorValasoulis, Georgeen_GB
dc.contributor.authorMartin, Maryen_GB
dc.contributor.authorvon Bünau, Güntheren_GB
dc.contributor.authorKyrgiou, Mariaen_GB
dc.contributor.authorParaskevaidis, Evangelosen_GB
dc.contributor.authorMartin-Hirsch, Pierre Len_GB
dc.contributor.authorPrendiville, Walter Jen_GB
dc.contributor.authorMartin, Francis Len_GB
dc.date.accessioned2014-07-17T14:47:10Z-
dc.date.available2014-07-17T14:47:10Z-
dc.date.issued2013-11-
dc.identifier.citationExploiting biospectroscopy as a novel screening tool for cervical cancer: towards a framework to validate its accuracy in a routine clinical setting. 2013, 5 (21):2697-711 Bioanalysisen_GB
dc.identifier.issn1757-6199-
dc.identifier.pmid24180508-
dc.identifier.doi10.4155/bio.13.233-
dc.identifier.urihttp://hdl.handle.net/10147/323382-
dc.description.abstractBiospectroscopy is an emerging field that harnesses the platform of physical sciences with computational analysis in order to shed novel insights on biological questions. An area where this approach seems to have potential is in screening or diagnostic clinical settings, where there is an urgent need for new approaches to objectively interrogate large numbers of samples in an objective fashion with acceptable levels of sensitivity and specificity. This review outlines the benefits of biospectroscopy in screening for precancer lesions of the cervix due to its ability to separate different grades of dysplasia. It evaluates the feasibility of introducing this technique into cervical screening programs on the basis of its ability to identify biomarkers of progression within derived spectra ('biochemical‑cell fingerprints').en_GB
dc.language.isoenen
dc.rightsArchived with thanks to Bioanalysisen_GB
dc.subjectCERVICAL CANCERen_GB
dc.titleExploiting biospectroscopy as a novel screening tool for cervical cancer: towards a framework to validate its accuracy in a routine clinical setting.en_GB
dc.typeArticleen
dc.identifier.journalBioanalysisen_GB
dc.description.fundingOtheren
dc.description.provinceLeinsteren
dc.description.peer-reviewpeer-reviewen

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