Trends in the incidence of lower extremity amputations in people with and without diabetes over a five-year period in the Republic of Ireland.

Hdl Handle:
http://hdl.handle.net/10147/322571
Title:
Trends in the incidence of lower extremity amputations in people with and without diabetes over a five-year period in the Republic of Ireland.
Authors:
Buckley, Claire M; O'Farrell, Anne; Canavan, Ronan J; Lynch, Anthony D; De La Harpe, Davida V; Bradley, Colin P; Perry, Ivan J
Citation:
Trends in the incidence of lower extremity amputations in people with and without diabetes over a five-year period in the Republic of Ireland. 2012, 7 (7):e41492 PLoS ONE
Journal:
PloS one
Issue Date:
2012
URI:
http://hdl.handle.net/10147/322571
DOI:
10.1371/journal.pone.0041492
PubMed ID:
22859991
Abstract:
To describe trends in the incidence of non-traumatic amputations among people with and without diabetes and estimate the relative risk of an individual with diabetes undergoing a lower extremity amputation compared to an individual without diabetes in the Republic of Ireland.; All adults who underwent a nontraumatic amputation during 2005 to 2009 were identified using HIPE (Hospital In-patient Enquiry) data. Participants were classified as having diabetes or not having diabetes. Incidence rates were calculated using the number of discharges for diabetes and non-diabetes related lower extremity amputations as the numerator and estimates of the resident population with and without diabetes as the denominator. Age-adjusted incidence rates were used for trend analysis.; Total diabetes-related amputation rates increased non-significantly during the study period; 144.2 in 2005 to 175.7 in 2009 per 100,000 people with diabetes (p = 0.11). Total non-diabetes related amputation rates dropped non-significantly from 12.0 in 2005 to 9.2 in 2009 per 100,000 people without diabetes (p = 0.16). An individual with diabetes was 22.3 (95% CI 19.1-26.1) times more likely to undergo a nontraumatic amputation than an individual without diabetes in 2005 and this did not change significantly by 2009.; This study provides the first national estimate of lower extremity amputation rates in the Republic of Ireland. Diabetes-related amputation rates have remained steady despite an increase in people with diabetes. These estimates provide a base-line and will allow follow-up over time.
Item Type:
Article
Language:
en
MeSH:
Amputation; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Foot; Humans; Incidence; Ireland; Leg; Length of Stay; Patient Discharge; Risk
ISSN:
1932-6203

Full metadata record

DC FieldValue Language
dc.contributor.authorBuckley, Claire Men_GB
dc.contributor.authorO'Farrell, Anneen_GB
dc.contributor.authorCanavan, Ronan Jen_GB
dc.contributor.authorLynch, Anthony Den_GB
dc.contributor.authorDe La Harpe, Davida Ven_GB
dc.contributor.authorBradley, Colin Pen_GB
dc.contributor.authorPerry, Ivan Jen_GB
dc.date.accessioned2014-07-08T09:25:17Z-
dc.date.available2014-07-08T09:25:17Z-
dc.date.issued2012-
dc.identifier.citationTrends in the incidence of lower extremity amputations in people with and without diabetes over a five-year period in the Republic of Ireland. 2012, 7 (7):e41492 PLoS ONEen_GB
dc.identifier.issn1932-6203-
dc.identifier.pmid22859991-
dc.identifier.doi10.1371/journal.pone.0041492-
dc.identifier.urihttp://hdl.handle.net/10147/322571-
dc.description.abstractTo describe trends in the incidence of non-traumatic amputations among people with and without diabetes and estimate the relative risk of an individual with diabetes undergoing a lower extremity amputation compared to an individual without diabetes in the Republic of Ireland.-
dc.description.abstractAll adults who underwent a nontraumatic amputation during 2005 to 2009 were identified using HIPE (Hospital In-patient Enquiry) data. Participants were classified as having diabetes or not having diabetes. Incidence rates were calculated using the number of discharges for diabetes and non-diabetes related lower extremity amputations as the numerator and estimates of the resident population with and without diabetes as the denominator. Age-adjusted incidence rates were used for trend analysis.-
dc.description.abstractTotal diabetes-related amputation rates increased non-significantly during the study period; 144.2 in 2005 to 175.7 in 2009 per 100,000 people with diabetes (p = 0.11). Total non-diabetes related amputation rates dropped non-significantly from 12.0 in 2005 to 9.2 in 2009 per 100,000 people without diabetes (p = 0.16). An individual with diabetes was 22.3 (95% CI 19.1-26.1) times more likely to undergo a nontraumatic amputation than an individual without diabetes in 2005 and this did not change significantly by 2009.-
dc.description.abstractThis study provides the first national estimate of lower extremity amputation rates in the Republic of Ireland. Diabetes-related amputation rates have remained steady despite an increase in people with diabetes. These estimates provide a base-line and will allow follow-up over time.-
dc.language.isoenen
dc.rightsArchived with thanks to PloS oneen_GB
dc.subject.meshAmputation-
dc.subject.meshDiabetes Mellitus, Type 1-
dc.subject.meshDiabetes Mellitus, Type 2-
dc.subject.meshDiabetic Foot-
dc.subject.meshHumans-
dc.subject.meshIncidence-
dc.subject.meshIreland-
dc.subject.meshLeg-
dc.subject.meshLength of Stay-
dc.subject.meshPatient Discharge-
dc.subject.meshRisk-
dc.titleTrends in the incidence of lower extremity amputations in people with and without diabetes over a five-year period in the Republic of Ireland.en_GB
dc.typeArticleen
dc.identifier.journalPloS oneen_GB

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