Perinatal outcomes of women with a prior history of unexplained recurrent miscarriage.

Hdl Handle:
http://hdl.handle.net/10147/319886
Title:
Perinatal outcomes of women with a prior history of unexplained recurrent miscarriage.
Authors:
Dempsey, Mark; Flood, Karen; Burke, Naomi; Fletcher, Patricia; Kirkham, Colin; Geary, Michael; Malone, Fergal D
Citation:
Dempsey M et al. Perinatal outcomes of women with a prior history of unexplained recurrent miscarriage. J. Matern. Fetal. Neonatal. Med. 2014:1-14
Journal:
The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians
Issue Date:
14-May-2014
URI:
http://hdl.handle.net/10147/319886
DOI:
10.3109/14767058.2014.923394
PubMed ID:
24824106
Abstract:
Abstract Objective: We sought to determine subsequent pregnancy outcomes in a cohort of women with a history of unexplained RM who were not receiving medical treatment. Study Design: This was a prospective cohort study, of women with a history of three unexplained consecutive first trimester losses, who were recruited and followed in their subsequent pregnancy. Control patients were healthy pregnant patients with no previous adverse perinatal outcome. Results: A total of 42 patients with a history of unexplained RM were recruited to the study. 9 (21.4%) experienced a further first trimester miscarriage, 1 case of ectopic and 1 case of partial molar pregnancy. 74% (23/31) of the RM cohort had a vaginal delivery. There was one case of severe pre-eclampsia. The RM group delivered at a mean gestational age of 38+2 weeks and with a mean birth-weight of 3.23kg. None of the neonates were under the 10(th) centile for gestational age. Overall, there was no significant difference in pregnancy outcomes between the two cohorts. Conclusion: Our study confirms the reassuring prognosis for achieving a live birth in the unexplained RM population with a very low incidence of adverse events with the majority delivering appropriately grown fetuses at term.
Item Type:
Article
Language:
en
Keywords:
PREGNANCY; CHILDBIRTH
Local subject classification:
MISCARRIAGE; PERINATAL OUTCOME
ISSN:
1476-4954

Full metadata record

DC FieldValue Language
dc.contributor.authorDempsey, Marken_GB
dc.contributor.authorFlood, Karenen_GB
dc.contributor.authorBurke, Naomien_GB
dc.contributor.authorFletcher, Patriciaen_GB
dc.contributor.authorKirkham, Colinen_GB
dc.contributor.authorGeary, Michaelen_GB
dc.contributor.authorMalone, Fergal Den_GB
dc.date.accessioned2014-06-05T11:22:30Z-
dc.date.available2014-06-05T11:22:30Z-
dc.date.issued2014-05-14-
dc.identifier.citationDempsey M et al. Perinatal outcomes of women with a prior history of unexplained recurrent miscarriage. J. Matern. Fetal. Neonatal. Med. 2014:1-14en_GB
dc.identifier.issn1476-4954-
dc.identifier.pmid24824106-
dc.identifier.doi10.3109/14767058.2014.923394-
dc.identifier.urihttp://hdl.handle.net/10147/319886-
dc.description.abstractAbstract Objective: We sought to determine subsequent pregnancy outcomes in a cohort of women with a history of unexplained RM who were not receiving medical treatment. Study Design: This was a prospective cohort study, of women with a history of three unexplained consecutive first trimester losses, who were recruited and followed in their subsequent pregnancy. Control patients were healthy pregnant patients with no previous adverse perinatal outcome. Results: A total of 42 patients with a history of unexplained RM were recruited to the study. 9 (21.4%) experienced a further first trimester miscarriage, 1 case of ectopic and 1 case of partial molar pregnancy. 74% (23/31) of the RM cohort had a vaginal delivery. There was one case of severe pre-eclampsia. The RM group delivered at a mean gestational age of 38+2 weeks and with a mean birth-weight of 3.23kg. None of the neonates were under the 10(th) centile for gestational age. Overall, there was no significant difference in pregnancy outcomes between the two cohorts. Conclusion: Our study confirms the reassuring prognosis for achieving a live birth in the unexplained RM population with a very low incidence of adverse events with the majority delivering appropriately grown fetuses at term.en_GB
dc.languageENG-
dc.language.isoenen
dc.rightsArchived with thanks to The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetriciansen_GB
dc.subjectPREGNANCYen_GB
dc.subjectCHILDBIRTHen_GB
dc.subject.otherMISCARRIAGEen_GB
dc.subject.otherPERINATAL OUTCOMEen_GB
dc.titlePerinatal outcomes of women with a prior history of unexplained recurrent miscarriage.en_GB
dc.typeArticleen
dc.identifier.journalThe journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetriciansen_GB
dc.description.fundingOtheren
dc.description.provinceLeinsteren
dc.description.peer-reviewpeer-reviewen

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