Management of parenteral nutrition associated hyperglycaemia: A comparison of subcutaneous and intravenous insulin regimen

Hdl Handle:
http://hdl.handle.net/10147/317073
Title:
Management of parenteral nutrition associated hyperglycaemia: A comparison of subcutaneous and intravenous insulin regimen
Authors:
Neff, K; Donegan, D; MacMahon, J; O’Hanlon, C; Keane, N; Agha, A; Thompson, C; Smith, D
Citation:
Neff K et al. Management of parenteral nutrition associated hyperglycaemia: A comparison of subcutaneous and intravenous insulin regimen. Ir Med J 2014 May 107(5)
Publisher:
Irish Medical Jorunal
Journal:
Irish Medical Journal
Issue Date:
May-2014
URI:
http://hdl.handle.net/10147/317073
Abstract:
PN is associated with significant hyperglycaemia, which may be detrimental to clinical outcome. There are few data on the management of this phenomenon outside of intensive care units. In our unit, we studied the efficacy of protocol-based intravenous insulin delivery as compared to subcutaneous insulin prescribed individually outside of the critical care setting. In a retrospective review over a two-year period, we compared patients with PN-associated hyperglycaemia who had received both modes of insulin therapy. A total of 122 who developed PN-associated hyperglycaemia were identified. Those on the intravenous insulin regimen were within glycaemic target for more time than those on the subcutaneous regimen (62% Vs 43%, p=0.008). We therefore conclude that outside of the critical care setting, intravenous insulin delivers better glycaemic control and should therefore be considered optimum therapy for patients with PN-associated hyperglycaemia.
Item Type:
Article
Language:
en
Keywords:
NUTRITION
Local subject classification:
HYPERGYLCAEMIA; INSULIN

Full metadata record

DC FieldValue Language
dc.contributor.authorNeff, Ken_GB
dc.contributor.authorDonegan, Den_GB
dc.contributor.authorMacMahon, Jen_GB
dc.contributor.authorO’Hanlon, Cen_GB
dc.contributor.authorKeane, Nen_GB
dc.contributor.authorAgha, Aen_GB
dc.contributor.authorThompson, Cen_GB
dc.contributor.authorSmith, Den_GB
dc.date.accessioned2014-05-16T11:42:45Z-
dc.date.available2014-05-16T11:42:45Z-
dc.date.issued2014-05-
dc.identifier.citationNeff K et al. Management of parenteral nutrition associated hyperglycaemia: A comparison of subcutaneous and intravenous insulin regimen. Ir Med J 2014 May 107(5)en_GB
dc.identifier.urihttp://hdl.handle.net/10147/317073-
dc.description.abstractPN is associated with significant hyperglycaemia, which may be detrimental to clinical outcome. There are few data on the management of this phenomenon outside of intensive care units. In our unit, we studied the efficacy of protocol-based intravenous insulin delivery as compared to subcutaneous insulin prescribed individually outside of the critical care setting. In a retrospective review over a two-year period, we compared patients with PN-associated hyperglycaemia who had received both modes of insulin therapy. A total of 122 who developed PN-associated hyperglycaemia were identified. Those on the intravenous insulin regimen were within glycaemic target for more time than those on the subcutaneous regimen (62% Vs 43%, p=0.008). We therefore conclude that outside of the critical care setting, intravenous insulin delivers better glycaemic control and should therefore be considered optimum therapy for patients with PN-associated hyperglycaemia.en_GB
dc.languageen-
dc.language.isoenen
dc.publisherIrish Medical Jorunalen_GB
dc.subjectNUTRITIONen_GB
dc.subject.otherHYPERGYLCAEMIAen_GB
dc.subject.otherINSULINen_GB
dc.titleManagement of parenteral nutrition associated hyperglycaemia: A comparison of subcutaneous and intravenous insulin regimenen_GB
dc.typeArticleen
dc.identifier.journalIrish Medical Journalen_GB
dc.description.fundingNo fundingen
dc.description.provinceLeinsteren
dc.description.peer-reviewpeer-reviewen
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