Hdl Handle:
http://hdl.handle.net/10147/315562
Title:
Vitamin D and neonatal immune function.
Authors:
Clancy, N; Onwuneme, C; Carroll, A; McCarthy, R; McKenna, M J; Murphy, N; Molloy, E J
Citation:
Vitamin D and neonatal immune function. 2013, 26 (7):639-46 J. Matern. Fetal. Neonatal. Med.
Journal:
The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians
Issue Date:
May-2013
URI:
http://hdl.handle.net/10147/315562
DOI:
10.3109/14767058.2012.746304
PubMed ID:
23131172
Additional Links:
http://informahealthcare.com/doi/abs/10.3109/14767058.2012.746304
Abstract:
Vitamin D deficiency is widespread in the neonatal and paediatric population of northern latitudes, particularly in children of African, Middle Eastern and Asian ethnicity. This is associated with diminished immune function and increases the risk of Th1 autoimmune diseases like type 1 diabetes. Epidermiological studies have also shown a link between vitamin D deficiency in children and a more severe course of illness with lower respiratory tract infection or Respiratory Syncitial Virus (RSV) bronchiolitis. The mechanism by which vitamin D enhances immunity is complex. It acts through the innate immune system by inducing antimicrobial peptides in epithelial cells, neutrophils and macrophages. The role of Vitamin D in neonatal and paediatric immunomodulation requires further study.
Item Type:
Article
Language:
en
Keywords:
NEONATE; NUTRITION
Local subject classification:
IMMUNOLOGY
MeSH:
Adaptive Immunity; Autoimmune Diseases; Child; Dietary Supplements; Female; Humans; Immunity, Innate; Infant, Newborn; Maternal-Fetal Exchange; Pregnancy; Vitamin D; Vitamin D Deficiency
ISSN:
1476-4954

Full metadata record

DC FieldValue Language
dc.contributor.authorClancy, Nen_GB
dc.contributor.authorOnwuneme, Cen_GB
dc.contributor.authorCarroll, Aen_GB
dc.contributor.authorMcCarthy, Ren_GB
dc.contributor.authorMcKenna, M Jen_GB
dc.contributor.authorMurphy, Nen_GB
dc.contributor.authorMolloy, E Jen_GB
dc.date.accessioned2014-04-10T09:24:48Z-
dc.date.available2014-04-10T09:24:48Z-
dc.date.issued2013-05-
dc.identifier.citationVitamin D and neonatal immune function. 2013, 26 (7):639-46 J. Matern. Fetal. Neonatal. Med.en_GB
dc.identifier.issn1476-4954-
dc.identifier.pmid23131172-
dc.identifier.doi10.3109/14767058.2012.746304-
dc.identifier.urihttp://hdl.handle.net/10147/315562-
dc.description.abstractVitamin D deficiency is widespread in the neonatal and paediatric population of northern latitudes, particularly in children of African, Middle Eastern and Asian ethnicity. This is associated with diminished immune function and increases the risk of Th1 autoimmune diseases like type 1 diabetes. Epidermiological studies have also shown a link between vitamin D deficiency in children and a more severe course of illness with lower respiratory tract infection or Respiratory Syncitial Virus (RSV) bronchiolitis. The mechanism by which vitamin D enhances immunity is complex. It acts through the innate immune system by inducing antimicrobial peptides in epithelial cells, neutrophils and macrophages. The role of Vitamin D in neonatal and paediatric immunomodulation requires further study.en_GB
dc.language.isoenen
dc.relation.urlhttp://informahealthcare.com/doi/abs/10.3109/14767058.2012.746304en_GB
dc.rightsArchived with thanks to The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetriciansen_GB
dc.subjectNEONATEen_GB
dc.subjectNUTRITIONen_GB
dc.subject.meshAdaptive Immunity-
dc.subject.meshAutoimmune Diseases-
dc.subject.meshChild-
dc.subject.meshDietary Supplements-
dc.subject.meshFemale-
dc.subject.meshHumans-
dc.subject.meshImmunity, Innate-
dc.subject.meshInfant, Newborn-
dc.subject.meshMaternal-Fetal Exchange-
dc.subject.meshPregnancy-
dc.subject.meshVitamin D-
dc.subject.meshVitamin D Deficiency-
dc.subject.otherIMMUNOLOGYen_GB
dc.titleVitamin D and neonatal immune function.en_GB
dc.typeArticleen
dc.identifier.journalThe journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetriciansen_GB
dc.description.fundingNo fundingen
dc.description.provinceLeinsteren
dc.description.peer-reviewpeer-reviewen

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