Hdl Handle:
http://hdl.handle.net/10147/315558
Title:
Toll-like receptors in neonatal sepsis.
Authors:
O'Hare, Fiona M; William Watson, R; Molloy, Eleanor J
Citation:
Toll-like receptors in neonatal sepsis. 2013, 102 (6):572-8 Acta Paediatr.
Journal:
Acta paediatrica
Issue Date:
Jun-2013
URI:
http://hdl.handle.net/10147/315558
DOI:
10.1111/apa.12201
PubMed ID:
23419040
Additional Links:
http://onlinelibrary.wiley.com/doi/10.1111/apa.12201/abstract
Abstract:
Toll-like receptors are vital transmembrane receptors that initiate the innate immune response to many micro-organisms. The discovery of these receptors has improved our understanding of host-pathogen interactions, and these receptors play an important role in the pathogenesis of multiple neonatal conditions such as sepsis and brain injury. Toll-like receptors, especially TLRs 2 and 4, are associated with necrotizing enterocolitis, periventricular leukomalacia and sepsis.
Item Type:
Article
Language:
en
Keywords:
NEONATE
Local subject classification:
IMMUNOLOGY; SEPSIS
MeSH:
Animals; Genetic Predisposition to Disease; Host-Pathogen Interactions; Humans; Immunity, Innate; Immunologic Factors; Infant, Newborn; Mycoses; Probiotics; Sepsis; Signal Transduction; Toll-Like Receptor 2; Toll-Like Receptor 4; Toll-Like Receptors
ISSN:
1651-2227

Full metadata record

DC FieldValue Language
dc.contributor.authorO'Hare, Fiona Men_GB
dc.contributor.authorWilliam Watson, Ren_GB
dc.contributor.authorMolloy, Eleanor Jen_GB
dc.date.accessioned2014-04-10T08:49:20Z-
dc.date.available2014-04-10T08:49:20Z-
dc.date.issued2013-06-
dc.identifier.citationToll-like receptors in neonatal sepsis. 2013, 102 (6):572-8 Acta Paediatr.en_GB
dc.identifier.issn1651-2227-
dc.identifier.pmid23419040-
dc.identifier.doi10.1111/apa.12201-
dc.identifier.urihttp://hdl.handle.net/10147/315558-
dc.description.abstractToll-like receptors are vital transmembrane receptors that initiate the innate immune response to many micro-organisms. The discovery of these receptors has improved our understanding of host-pathogen interactions, and these receptors play an important role in the pathogenesis of multiple neonatal conditions such as sepsis and brain injury. Toll-like receptors, especially TLRs 2 and 4, are associated with necrotizing enterocolitis, periventricular leukomalacia and sepsis.en_GB
dc.language.isoenen
dc.relation.urlhttp://onlinelibrary.wiley.com/doi/10.1111/apa.12201/abstracten_GB
dc.rightsArchived with thanks to Acta paediatrica (Oslo, Norway : 1992)en_GB
dc.subjectNEONATEen_GB
dc.subject.meshAnimals-
dc.subject.meshGenetic Predisposition to Disease-
dc.subject.meshHost-Pathogen Interactions-
dc.subject.meshHumans-
dc.subject.meshImmunity, Innate-
dc.subject.meshImmunologic Factors-
dc.subject.meshInfant, Newborn-
dc.subject.meshMycoses-
dc.subject.meshProbiotics-
dc.subject.meshSepsis-
dc.subject.meshSignal Transduction-
dc.subject.meshToll-Like Receptor 2-
dc.subject.meshToll-Like Receptor 4-
dc.subject.meshToll-Like Receptors-
dc.subject.otherIMMUNOLOGYen_GB
dc.subject.otherSEPSISen_GB
dc.titleToll-like receptors in neonatal sepsis.en_GB
dc.typeArticleen
dc.identifier.journalActa paediatricaen_GB
dc.description.fundingNo fundingen
dc.description.provinceLeinsteren
dc.description.peer-reviewpeer-reviewen

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