Hdl Handle:
http://hdl.handle.net/10147/313528
Title:
Asthma and cystic fibrosis: A tangled web.
Authors:
Kent, Brian D; Lane, Stephen J; van Beek, Edwin J; Dodd, Jonathan D; Costello, Richard W; Tiddens, Harm A W M
Citation:
Asthma and cystic fibrosis: A tangled web. 2014, 49 (3):205-13 Pediatr. Pulmonol.
Journal:
Pediatric pulmonology
Issue Date:
Mar-2014
URI:
http://hdl.handle.net/10147/313528
DOI:
10.1002/ppul.22934
PubMed ID:
24420817
Abstract:
Successfully diagnosing concomitant asthma in people with cystic fibrosis (CF) is a challenging proposition, and the utility of conventional diagnostic criteria of asthma in CF populations remains uncertain. Nonetheless, the accurate identification of individuals with CF and asthma allows appropriate tailoring of therapy, and should reduce the unnecessary use of asthma medication in broader CF cohorts. In this review, we discuss the diagnostic challenge posed by asthma in CF, both in terms of clinical evaluation, and of interpretation of pulmonary function testing and non-invasive markers of airway inflammation. We also examine how the role of cross-sectional thoracic imaging in CF and asthma can assist in the diagnosis of asthma in these patients. Finally, we critically appraise the evidence base behind the use of asthma medications in CF populations, with a particular focus on the use of inhaled corticosteroids and bronchodilators. As shall be discussed, the gaps in the current literature make further high-quality research in this field imperative. Pediatr Pulmonol. 2014; 49:205-213. © 2014 Wiley Periodicals, Inc.
Item Type:
Article
Language:
en
Keywords:
ASTHMA; CYSTIC FIBROSIS
ISSN:
1099-0496

Full metadata record

DC FieldValue Language
dc.contributor.authorKent, Brian Den_GB
dc.contributor.authorLane, Stephen Jen_GB
dc.contributor.authorvan Beek, Edwin Jen_GB
dc.contributor.authorDodd, Jonathan Den_GB
dc.contributor.authorCostello, Richard Wen_GB
dc.contributor.authorTiddens, Harm A W Men_GB
dc.date.accessioned2014-02-28T15:56:53Z-
dc.date.available2014-02-28T15:56:53Z-
dc.date.issued2014-03-
dc.identifier.citationAsthma and cystic fibrosis: A tangled web. 2014, 49 (3):205-13 Pediatr. Pulmonol.en_GB
dc.identifier.issn1099-0496-
dc.identifier.pmid24420817-
dc.identifier.doi10.1002/ppul.22934-
dc.identifier.urihttp://hdl.handle.net/10147/313528-
dc.description.abstractSuccessfully diagnosing concomitant asthma in people with cystic fibrosis (CF) is a challenging proposition, and the utility of conventional diagnostic criteria of asthma in CF populations remains uncertain. Nonetheless, the accurate identification of individuals with CF and asthma allows appropriate tailoring of therapy, and should reduce the unnecessary use of asthma medication in broader CF cohorts. In this review, we discuss the diagnostic challenge posed by asthma in CF, both in terms of clinical evaluation, and of interpretation of pulmonary function testing and non-invasive markers of airway inflammation. We also examine how the role of cross-sectional thoracic imaging in CF and asthma can assist in the diagnosis of asthma in these patients. Finally, we critically appraise the evidence base behind the use of asthma medications in CF populations, with a particular focus on the use of inhaled corticosteroids and bronchodilators. As shall be discussed, the gaps in the current literature make further high-quality research in this field imperative. Pediatr Pulmonol. 2014; 49:205-213. © 2014 Wiley Periodicals, Inc.en_GB
dc.language.isoenen
dc.rightsArchived with thanks to Pediatric pulmonologyen_GB
dc.subjectASTHMAen_GB
dc.subjectCYSTIC FIBROSISen_GB
dc.titleAsthma and cystic fibrosis: A tangled web.en_GB
dc.typeArticleen
dc.identifier.journalPediatric pulmonologyen_GB
dc.description.fundingNo fundingen
dc.description.provinceLeinsteren
dc.description.peer-reviewpeer-reviewen

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