Efficacy of Adalimumab as a long term maintenance therapy in ulcerative colitis.
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Affiliation
Centre for Colorectal Disease, St. Vincent's University Hospital, Elm Park, Dublin 4, Ireland. edelmcdermott@physicians.ieIssue Date
2013-03MeSH
AdultAged
Anti-Inflammatory Agents, Non-Steroidal
Antibodies, Monoclonal, Humanized
Colectomy
Colitis, Ulcerative
Female
Follow-Up Studies
Humans
Maintenance Chemotherapy
Male
Middle Aged
Retrospective Studies
Time Factors
Treatment Failure
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Efficacy of Adalimumab as a long term maintenance therapy in ulcerative colitis. 2013, 7 (2):150-3 J Crohns ColitisJournal
Journal of Crohn's & colitisDOI
10.1016/j.crohns.2012.03.016PubMed ID
22520592Abstract
Adalimumab is a recombinant human IgG1 monoclonal antibody to TNF-alpha. There are limited data with regard to its efficacy in ulcerative colitis. We report experience of adalimumab in ulcerative colitis in a single centre with a focus on the ability of this agent to maintain response and avoid colectomy in the medium to long-term.Item Type
ArticleLanguage
enISSN
1876-4479ae974a485f413a2113503eed53cd6c53
10.1016/j.crohns.2012.03.016
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