Browsing Health and Wellbeing by Title
Now showing items 1-20 of 91
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Aerobic exercise intensity does not affect the anabolic signaling following resistance exercise in endurance athletes.This study examined whether intensity of endurance stimulus within a concurrent training paradigm influenced the phosphorylation of signaling proteins associated with the mTOR and AMPK networks. Eight male cyclists completed (1) resistance exercise (RES), 6 × 8 squats at 80% 1-RM; (2) resistance exercise and moderate intensity cycling of 40 min at 65% V̇O2peak, (RES + MIC); (3) resistance exercise and high intensity interval cycling of 40 min with 6 alternating 3 min intervals of 85 and 45% V̇O2peak (RES + HIIC), in a cross-over design. Muscle biopsies were collected at rest and 3 h post-RES. There was a main effect of condition for mTORS2448 (p = 0.043), with a greater response in the RES + MIC relative to RES condition (p = 0.033). There was a main effect of condition for AMPKα2T172 (p = 0.041), with a greater response in RES + MIC, relative to both RES + HIIC (p = 0.026) and RES (p = 0.046). There were no other condition effects for the remaining protein kinases assessed (p > 0.05). These data do not support a molecular interference effect in cyclists under controlled conditions. There was no intensity-dependent regulation of AMPK, nor differential activation of anabolism with the manipulation of endurance exercise intensity.
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Agreement between An Inertia and Optical Based Motion Capture during the VU-Return-to-Play- Field-Test.The validity of an inertial sensor-based motion capture system (IMC) has not been examined within the demands of a sports-specific field movement test. This study examined the validity of an IMC during a field test (VU®) by comparing it to an optical marker-based motion capture system (MMC). Expected accuracy and precision benchmarks were computed by comparing the outcomes of a linear and functional joint fitting model within the MMC. The kinematics from the IMC in sagittal plane demonstrated correlations (r2) between 0.76 and 0.98 with root mean square differences (RMSD) < 5, only the knee bias was within the benchmark. In the frontal plane, r2 ranged between 0.13 and 0.80 with RMSD < 10, while the knee and hip bias was within the benchmark. For the transversal plane, r2 ranged 0.11 to 0.93 with RMSD < 7, while the ankle, knee and hip bias remained within the benchmark. The findings indicate that ankle kinematics are not interchangeable with MMC, that hip flexion and pelvis tilt higher in IMC than MMC, while other measures are comparable to MMC. Higher pelvis tilt/hip flexion in the IMC can be explained by a one sensor tilt estimation, while ankle kinematics demonstrated a considerable level of disagreement, which is likely due to four reasons: A one sensor estimation, sensor/marker attachment, movement artefacts of shoe sole and the ankle model used.
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Assessment of Radiation Dose from the Consumption of Bottled Drinking Water in Japan.Activity concentrations of 234U, 235U, 238U, 226Ra, 228Ra, 222Rn, 210Po, 210Pb, 40K, 3H, 14C, 134Cs and 137Cs were determined in 20 different Japanese bottled drinking water commercially available in Japan. The origins of the mineral water samples were geographically distributed across different regions of Japan. Activity concentrations above detection limits were measured for the radionuclides 234U, 235U, 238U, 226Ra, 228Ra and 210Po. An average total annual effective dose due to ingestion was estimated for adults, based on the average annual volume of bottled water consumed in Japan in 2019, reported to be 31.7 L/y per capita. The estimated dose was found to be below the recommended World Health Organisation (WHO) guidance level of 0.1 mSv/y for drinking water quality. The most significant contributor to the estimated dose was 228Ra.
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Comparative Genomics Analysis of from Different Niches.The potential probiotic benefits of Lactobacillus mucosae have received increasing attention. To investigate the genetic diversity of L. mucosae, comparative genomic analyses of 93 strains isolated from different niches (human and animal gut, human vagina, etc.) and eight strains of published genomes were conducted. The results showed that the core genome of L. mucosae mainly encoded translation and transcription, amino acid biosynthesis, sugar metabolism, and defense function while the pan-genomic curve tended to be close. The genetic diversity of L. mucosae mainly reflected in carbohydrate metabolism and immune/competitive-related factors, such as exopolysaccharide (EPS), enterolysin A, and clustered regularly interspaced short palindromic repeats (CRISPR)-Cas. It was worth noting that this research firstly predicted the complete EPS operon shared among L. mucosae. Additionally, the type IIIA CRISPR-Cas system was discovered in L. mucosae for the first time. This work provided new ideas for the study of this species.
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Cross-sectional association of dietary water intakes and sources, and adiposity: National Adult Nutrition Survey, the Republic of Ireland.Cross-sectional study of 1500 adults aged 18-90 years (Irish National Adult Nutrition Survey, 2008-2010). Total water intake and its sources were estimated using food records. Associations of total water, drinking water, beverage moisture and food moisture intakes split by tertile, and BMI (kg/m2), waist circumference (cm), and bio-impedance derived body fat (%) were evaluated using covariate-adjusted linear regression analyses including adjustment for energy intake and energy expenditure.