Perinatal treponema pallidum: Evidence based guidelines to reduce mother to child transmission

Hdl Handle:
http://hdl.handle.net/10147/311963
Title:
Perinatal treponema pallidum: Evidence based guidelines to reduce mother to child transmission
Authors:
Freyne, B; Stafford, A; Knowles, S; O’ Hora, A; Molloy, E
Publisher:
Irish Medical Journal (IMJ)
Journal:
Irish Medical Journal (IMJ)
Issue Date:
Jan-2014
URI:
http://hdl.handle.net/10147/311963
Abstract:
Universal antenatal screening for T. pallidum is standard in Irish maternity units. The prevalence of adult syphilis has increased in Ireland. We audited the neonatal management of infants exposed to T. pallidum in utero. A cross sectional retrospective analysis of all pregnancies with confirmed positive serology for T. pallidum from January 2005 to December 2010 was conducted at the National Maternity Hospital, Holles St. Data were analysed using SPSS 14.0. Ethical approval was obtained. There were 55,058 live births during the study period. Fifty-eight women had positive serology and 41 met inclusion criteria. Infant evaluation and follow up was decided by allocation to an evidence based algorithm. Twenty-one infants (51%) were accurately allocated and assessed, 5 (12%) had a partial assessment and the algorithm was incorrectly applied in 15 (36%) of cases. Failure to adhere to evidence based neonatal guidelines is common and undermines efficacy of the screening program.
Item Type:
Article
Language:
en
Keywords:
PREGNANCY; NEONATE; COMMUNICABLE DISEASE; MOTHER

Full metadata record

DC FieldValue Language
dc.contributor.authorFreyne, Ben_GB
dc.contributor.authorStafford, Aen_GB
dc.contributor.authorKnowles, Sen_GB
dc.contributor.authorO’ Hora, Aen_GB
dc.contributor.authorMolloy, Een_GB
dc.date.accessioned2014-01-28T11:06:55Z-
dc.date.available2014-01-28T11:06:55Z-
dc.date.issued2014-01-
dc.identifier.urihttp://hdl.handle.net/10147/311963-
dc.description.abstractUniversal antenatal screening for T. pallidum is standard in Irish maternity units. The prevalence of adult syphilis has increased in Ireland. We audited the neonatal management of infants exposed to T. pallidum in utero. A cross sectional retrospective analysis of all pregnancies with confirmed positive serology for T. pallidum from January 2005 to December 2010 was conducted at the National Maternity Hospital, Holles St. Data were analysed using SPSS 14.0. Ethical approval was obtained. There were 55,058 live births during the study period. Fifty-eight women had positive serology and 41 met inclusion criteria. Infant evaluation and follow up was decided by allocation to an evidence based algorithm. Twenty-one infants (51%) were accurately allocated and assessed, 5 (12%) had a partial assessment and the algorithm was incorrectly applied in 15 (36%) of cases. Failure to adhere to evidence based neonatal guidelines is common and undermines efficacy of the screening program.en_GB
dc.language.isoenen
dc.publisherIrish Medical Journal (IMJ)en_GB
dc.subjectPREGNANCYen_GB
dc.subjectNEONATEen_GB
dc.subjectCOMMUNICABLE DISEASEen_GB
dc.subjectMOTHERen_GB
dc.titlePerinatal treponema pallidum: Evidence based guidelines to reduce mother to child transmissionen_GB
dc.typeArticleen
dc.identifier.journalIrish Medical Journal (IMJ)en_GB
dc.description.fundingNo fundingen
dc.description.provinceLeinsteren
dc.description.peer-reviewpeer-reviewen
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