Advances in the diagnosis and management of asthma in older adults.

Hdl Handle:
http://hdl.handle.net/10147/311128
Title:
Advances in the diagnosis and management of asthma in older adults.
Authors:
Al-Alawi, Mazen; Hassan, Tidi; Chotirmall, Sanjay H
Citation:
Advances in the Diagnosis and Management Of Asthma in Older Adults. 2013: Am. J. Med.
Journal:
The American journal of medicine
Issue Date:
28-Dec-2013
URI:
http://hdl.handle.net/10147/311128
DOI:
10.1016/j.amjmed.2013.12.013
PubMed ID:
24380710
Abstract:
Global estimates on ageing predict an increased burden of asthma in the older population. Consequently, its recognition, diagnosis and management in clinical practice require optimization. This review aims to provide an update for clinicians highlighting advances in the understanding of the ageing process and immunosenescence together with their applicability to asthma from a diagnostic and therapeutic perspective. Ageing impacts airway responses, immune function and influences efficacy of emerging phenotype-specific therapies when applied to the elderly patient. Differentiating eosinophilic and neutrophilic disease accounts for atopic illness and distinguishes long-standing from late-onset asthma. Therapeutic challenges in drug delivery, treatment adherence and side effect profiles persist in the older patient while novel recording devices developed to aid detection of an adequate inhalation evaluates treatment effectiveness and compliance more accurately than previously attainable. Anti-cytokine therapies improve control of brittle asthma while bronchial thermoplasty is an option in refractory cases. Multi-dimensional intervention strategies prove best in the management of asthma in the older adult which remains a condition that is not rare but rarely diagnosed in this patient population.
Item Type:
Article
Language:
en
Keywords:
ASTHMA; OLDER PEOPLE
ISSN:
1555-7162

Full metadata record

DC FieldValue Language
dc.contributor.authorAl-Alawi, Mazenen_GB
dc.contributor.authorHassan, Tidien_GB
dc.contributor.authorChotirmall, Sanjay Hen_GB
dc.date.accessioned2014-01-09T12:25:53Z-
dc.date.available2014-01-09T12:25:53Z-
dc.date.issued2013-12-28-
dc.identifier.citationAdvances in the Diagnosis and Management Of Asthma in Older Adults. 2013: Am. J. Med.en_GB
dc.identifier.issn1555-7162-
dc.identifier.pmid24380710-
dc.identifier.doi10.1016/j.amjmed.2013.12.013-
dc.identifier.urihttp://hdl.handle.net/10147/311128-
dc.description.abstractGlobal estimates on ageing predict an increased burden of asthma in the older population. Consequently, its recognition, diagnosis and management in clinical practice require optimization. This review aims to provide an update for clinicians highlighting advances in the understanding of the ageing process and immunosenescence together with their applicability to asthma from a diagnostic and therapeutic perspective. Ageing impacts airway responses, immune function and influences efficacy of emerging phenotype-specific therapies when applied to the elderly patient. Differentiating eosinophilic and neutrophilic disease accounts for atopic illness and distinguishes long-standing from late-onset asthma. Therapeutic challenges in drug delivery, treatment adherence and side effect profiles persist in the older patient while novel recording devices developed to aid detection of an adequate inhalation evaluates treatment effectiveness and compliance more accurately than previously attainable. Anti-cytokine therapies improve control of brittle asthma while bronchial thermoplasty is an option in refractory cases. Multi-dimensional intervention strategies prove best in the management of asthma in the older adult which remains a condition that is not rare but rarely diagnosed in this patient population.-
dc.languageENG-
dc.language.isoenen
dc.rightsArchived with thanks to The American journal of medicineen_GB
dc.subjectASTHMAen_GB
dc.subjectOLDER PEOPLEen_GB
dc.titleAdvances in the diagnosis and management of asthma in older adults.en_GB
dc.typeArticleen
dc.identifier.journalThe American journal of medicineen_GB
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