Are calcium channel blockers safe in hypertension? Council on High Blood Pressure of the Irish Heart Foundation practice statement

Hdl Handle:
http://hdl.handle.net/10147/310946
Title:
Are calcium channel blockers safe in hypertension? Council on High Blood Pressure of the Irish Heart Foundation practice statement
Authors:
Irish Heart Foundation
Publisher:
Irish Heart Foundation
Issue Date:
2002
URI:
http://hdl.handle.net/10147/310946
Item Type:
Other
Language:
en
Description:
Calcium channel blockers have been extensively used for many years in the treatment of hypertension and ischaemic heart disease. Their popularity is largely based on their potent anti-hypertensive effect and their considerable efficacy as anti-anginal agents, and their purported lack of side-effects. However, in the past year, several articles have appeared in the medical literature, casting doubt on the safety of calcium channel blocker drugs, initially in patients with cardiovascular disease, and subsequently in the patient population in general. These papers sparked a series of critical reviews and somewhat emotive correspondences, regarding the subject matter of the articles, and in some cases, personal criticisms of the authors. The primary result of this has been to highlight in the minds of the public and the prescribing physician a question-mark regarding the safety of these drugs. The controversy, which has been the subject of a number of reviews, has centered on whether or not the use of these drugs might be associated with an excess cardiac mortality, gastrointestinal bleeding and cancers of various kinds. An extensive review of the literature on this controversial subject permits at least the formulation of recommendations which it must be acknowledged may change in the light of evidence from a number of on-going trials.
Keywords:
HYPERTENSION; CARDIOVASCULAR DISEASE

Full metadata record

DC FieldValue Language
dc.contributor.authorIrish Heart Foundationen_GB
dc.date.accessioned2014-01-06T16:31:37Z-
dc.date.available2014-01-06T16:31:37Z-
dc.date.issued2002-
dc.identifier.urihttp://hdl.handle.net/10147/310946-
dc.descriptionCalcium channel blockers have been extensively used for many years in the treatment of hypertension and ischaemic heart disease. Their popularity is largely based on their potent anti-hypertensive effect and their considerable efficacy as anti-anginal agents, and their purported lack of side-effects. However, in the past year, several articles have appeared in the medical literature, casting doubt on the safety of calcium channel blocker drugs, initially in patients with cardiovascular disease, and subsequently in the patient population in general. These papers sparked a series of critical reviews and somewhat emotive correspondences, regarding the subject matter of the articles, and in some cases, personal criticisms of the authors. The primary result of this has been to highlight in the minds of the public and the prescribing physician a question-mark regarding the safety of these drugs. The controversy, which has been the subject of a number of reviews, has centered on whether or not the use of these drugs might be associated with an excess cardiac mortality, gastrointestinal bleeding and cancers of various kinds. An extensive review of the literature on this controversial subject permits at least the formulation of recommendations which it must be acknowledged may change in the light of evidence from a number of on-going trials.en_GB
dc.language.isoenen
dc.publisherIrish Heart Foundationen_GB
dc.subjectHYPERTENSIONen_GB
dc.subjectCARDIOVASCULAR DISEASEen_GB
dc.titleAre calcium channel blockers safe in hypertension? Council on High Blood Pressure of the Irish Heart Foundation practice statementen_GB
dc.typeOtheren
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