Neutrophil gelatinase-associated lipocalin and albuminuria as predictors of acute kidney injury in patients treated with goal-directed haemodynamic therapy after major abdominal surgery.

Hdl Handle:
http://hdl.handle.net/10147/305726
Title:
Neutrophil gelatinase-associated lipocalin and albuminuria as predictors of acute kidney injury in patients treated with goal-directed haemodynamic therapy after major abdominal surgery.
Authors:
Cullen, Mr; Jhanji, S; Pearse, Rm; Fitzgibbon, Mc
Affiliation:
Department of Clinical Biochemistry and Diagnostic Endocrinology, Mater Misericordiae University Hospital, Dublin, Republic of Ireland.
Citation:
Neutrophil gelatinase-associated lipocalin and albuminuria as predictors of acute kidney injury in patients treated with goal-directed haemodynamic therapy after major abdominal surgery. 2013: Ann. Clin. Biochem.
Journal:
Annals of clinical biochemistry
Issue Date:
11-Oct-2013
URI:
http://hdl.handle.net/10147/305726
DOI:
10.1177/0004563213507438
PubMed ID:
24123926
Abstract:
Neutrophil gelatinase-associated lipocalin (NGAL) is emerging as a new biomarker for the early identification of acute kidney injury (AKI). There is also increasing evidence of an association between urinary albumin/creatinine ratio (ACR) and AKI. The primary aim of this study was to evaluate the clinical utility of these biomarkers to predict AKI in a population of perioperative patients treated with goal-directed haemodynamic therapy (GDHT). Secondary aims were to examine NGAL and ACR as sensitive biomarkers to detect the effects of GDHT and to investigate the association of these biomarkers with secondary outcomes.
Item Type:
Article
Language:
en
Local subject classification:
ENDOCRINOLOGY; BIOCHEMISTRY
ISSN:
1758-1001

Full metadata record

DC FieldValue Language
dc.contributor.authorCullen, Mren_GB
dc.contributor.authorJhanji, Sen_GB
dc.contributor.authorPearse, Rmen_GB
dc.contributor.authorFitzgibbon, Mcen_GB
dc.date.accessioned2013-11-25T11:39:00Z-
dc.date.available2013-11-25T11:39:00Z-
dc.date.issued2013-10-11-
dc.identifier.citationNeutrophil gelatinase-associated lipocalin and albuminuria as predictors of acute kidney injury in patients treated with goal-directed haemodynamic therapy after major abdominal surgery. 2013: Ann. Clin. Biochem.en_GB
dc.identifier.issn1758-1001-
dc.identifier.pmid24123926-
dc.identifier.doi10.1177/0004563213507438-
dc.identifier.urihttp://hdl.handle.net/10147/305726-
dc.description.abstractNeutrophil gelatinase-associated lipocalin (NGAL) is emerging as a new biomarker for the early identification of acute kidney injury (AKI). There is also increasing evidence of an association between urinary albumin/creatinine ratio (ACR) and AKI. The primary aim of this study was to evaluate the clinical utility of these biomarkers to predict AKI in a population of perioperative patients treated with goal-directed haemodynamic therapy (GDHT). Secondary aims were to examine NGAL and ACR as sensitive biomarkers to detect the effects of GDHT and to investigate the association of these biomarkers with secondary outcomes.en_GB
dc.languageENG-
dc.language.isoenen
dc.rightsArchived with thanks to Annals of clinical biochemistryen_GB
dc.subject.otherENDOCRINOLOGYen_GB
dc.subject.otherBIOCHEMISTRYen_GB
dc.titleNeutrophil gelatinase-associated lipocalin and albuminuria as predictors of acute kidney injury in patients treated with goal-directed haemodynamic therapy after major abdominal surgery.en_GB
dc.typeArticleen
dc.contributor.departmentDepartment of Clinical Biochemistry and Diagnostic Endocrinology, Mater Misericordiae University Hospital, Dublin, Republic of Ireland.en_GB
dc.identifier.journalAnnals of clinical biochemistryen_GB
dc.description.fundingNo fundingen
dc.description.provinceLeinsteren
dc.description.peer-reviewpeer-reviewen
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