VGKC positive autoimmune encephalopathy mimicking dementia.

Hdl Handle:
http://hdl.handle.net/10147/305274
Title:
VGKC positive autoimmune encephalopathy mimicking dementia.
Authors:
Molloy, Anna; Cassidy, Eugene; Ryan, Aisling; O' Toole, Orna
Affiliation:
Neurology Department, Cork University Hospital, Cork, Ireland. annamolusa@gmail.com
Citation:
VGKC positive autoimmune encephalopathy mimicking dementia. 2011, 2011: BMJ Case Rep
Journal:
BMJ case reports
Issue Date:
2011
URI:
http://hdl.handle.net/10147/305274
DOI:
10.1136/bcr.08.2011.4642
PubMed ID:
22674939
Abstract:
Voltage gated potassium channel antibodies (VGKC Abs) are known to cause three rare neurological syndromes- neuromyotonia, Morvan's syndrome and limbic encephalitis although an increasing array of other associated neurological symptoms are becoming recognised. The authors describe the case of a 60-year-old female who presented to the neurology clinic with an apparent early onset dementing process. She was noted to have both extrapyramidal and frontal release signs on examination and was admitted for further evaluation. Her dementia investigation including a neoplastic screen was negative except for VGKC antibody positivity. Her symptoms dramatically improved with commencement of immunosuppression. A non-paraneoplastic VGKC antibody associated dementia-like syndrome has rarely been described. The authors add to the few existing reports of what represents an important reversible cause of cognitive impairment.
Item Type:
Article
Language:
en
Keywords:
NEUROLOGICAL DISEASE AND DISORDER
MeSH:
Antibodies; Autoimmune Diseases; Azathioprine; Bipolar Disorder; Brain Diseases; Dementia; Diagnosis, Differential; Female; Humans; Immunosuppressive Agents; Middle Aged; Potassium Channels, Voltage-Gated
ISSN:
1757-790X

Full metadata record

DC FieldValue Language
dc.contributor.authorMolloy, Annaen_GB
dc.contributor.authorCassidy, Eugeneen_GB
dc.contributor.authorRyan, Aislingen_GB
dc.contributor.authorO' Toole, Ornaen_GB
dc.date.accessioned2013-11-12T16:20:09Z-
dc.date.available2013-11-12T16:20:09Z-
dc.date.issued2011-
dc.identifier.citationVGKC positive autoimmune encephalopathy mimicking dementia. 2011, 2011: BMJ Case Repen_GB
dc.identifier.issn1757-790X-
dc.identifier.pmid22674939-
dc.identifier.doi10.1136/bcr.08.2011.4642-
dc.identifier.urihttp://hdl.handle.net/10147/305274-
dc.description.abstractVoltage gated potassium channel antibodies (VGKC Abs) are known to cause three rare neurological syndromes- neuromyotonia, Morvan's syndrome and limbic encephalitis although an increasing array of other associated neurological symptoms are becoming recognised. The authors describe the case of a 60-year-old female who presented to the neurology clinic with an apparent early onset dementing process. She was noted to have both extrapyramidal and frontal release signs on examination and was admitted for further evaluation. Her dementia investigation including a neoplastic screen was negative except for VGKC antibody positivity. Her symptoms dramatically improved with commencement of immunosuppression. A non-paraneoplastic VGKC antibody associated dementia-like syndrome has rarely been described. The authors add to the few existing reports of what represents an important reversible cause of cognitive impairment.en_GB
dc.language.isoenen
dc.rightsArchived with thanks to BMJ case reportsen_GB
dc.subjectNEUROLOGICAL DISEASE AND DISORDERen_GB
dc.subject.meshAntibodies-
dc.subject.meshAutoimmune Diseases-
dc.subject.meshAzathioprine-
dc.subject.meshBipolar Disorder-
dc.subject.meshBrain Diseases-
dc.subject.meshDementia-
dc.subject.meshDiagnosis, Differential-
dc.subject.meshFemale-
dc.subject.meshHumans-
dc.subject.meshImmunosuppressive Agents-
dc.subject.meshMiddle Aged-
dc.subject.meshPotassium Channels, Voltage-Gated-
dc.titleVGKC positive autoimmune encephalopathy mimicking dementia.en_GB
dc.typeArticleen
dc.contributor.departmentNeurology Department, Cork University Hospital, Cork, Ireland. annamolusa@gmail.comen_GB
dc.identifier.journalBMJ case reportsen_GB
dc.description.fundingNo fundingen
dc.description.provinceMunsteren
dc.description.peer-reviewpeer-reviewen

Related articles on PubMed

All Items in Lenus, The Irish Health Repository are protected by copyright, with all rights reserved, unless otherwise indicated.