Association between Sleep Disruption and Levels of Lipids in Caucasians with Type 2 Diabetes.

Hdl Handle:
http://hdl.handle.net/10147/303751
Title:
Association between Sleep Disruption and Levels of Lipids in Caucasians with Type 2 Diabetes.
Authors:
Wan Mahmood, Wan Aizad; Draman Yusoff, Mohd Shazli; Behan, Lucy Ann; Di Perna, Andrea; Kyaw Tun, Tommy; McDermott, John; Sreenan, Seamus
Affiliation:
Department of Endocrinology and Diabetes, Royal College of Surgeons in Ireland, Connolly Hospital, Blanchardstown, Dublin 15, Ireland.
Citation:
Association between Sleep Disruption and Levels of Lipids in Caucasians with Type 2 Diabetes. 2013, 2013:341506 Int J Endocrinol
Journal:
International journal of endocrinology
Issue Date:
29-Aug-2013
URI:
http://hdl.handle.net/10147/303751
DOI:
10.1155/2013/341506
PubMed ID:
24072996
Additional Links:
http://www.hindawi.com/journals/ije/2013/341506/
Abstract:
Aim. To investigate the association between sleep quality and duration with lipid and glycaemic control in Caucasian subjects with type 2 diabetes. Methods. Sleep quality was assessed using the Pittsburgh Sleep Quality Index (PSQI) in 114 type 2 diabetes (T2DM) subjects. Comparisons were made between subjects with different sleep quality and sleep duration. Hierarchical multiple regression analyses were used to determine contributors to metabolic parameters. Results. Subjects with poor sleep quality (PQ; PSQI ≥ 6) had higher systolic blood pressure, glycated haemoglobin, urine albumin : creatinine ratio (UAC), total cholesterol (TC), and triglycerides (TG) (P < 0.05 for all) compared to those with good sleep quality (GQ; PSQI ≤ 5). Long sleep duration (LSD) subjects had higher TC and short sleep duration (SSD) subjects had higher TG compared to those with medium sleep duration. Sleep duration and PSQI score were independent predictors of TC and low-density lipoprotein cholesterol (LDL), contributing to 14.0% and 6.1% of the total variance, respectively. Conclusions. In this Caucasian T2DM population, PQ is associated with adverse cardiovascular risk markers, and long and short sleep disruptions have an independent negative impact on lipids. Sleep assessment should be included as part of a diabetes clinic review.
Item Type:
Article
Language:
en
Keywords:
SLEEP DISORDER; DIABETES
ISSN:
1687-8337

Full metadata record

DC FieldValue Language
dc.contributor.authorWan Mahmood, Wan Aizaden_GB
dc.contributor.authorDraman Yusoff, Mohd Shazlien_GB
dc.contributor.authorBehan, Lucy Annen_GB
dc.contributor.authorDi Perna, Andreaen_GB
dc.contributor.authorKyaw Tun, Tommyen_GB
dc.contributor.authorMcDermott, Johnen_GB
dc.contributor.authorSreenan, Seamusen_GB
dc.date.accessioned2013-10-21T13:20:12Z-
dc.date.available2013-10-21T13:20:12Z-
dc.date.issued2013-08-29-
dc.identifier.citationAssociation between Sleep Disruption and Levels of Lipids in Caucasians with Type 2 Diabetes. 2013, 2013:341506 Int J Endocrinolen_GB
dc.identifier.issn1687-8337-
dc.identifier.pmid24072996-
dc.identifier.doi10.1155/2013/341506-
dc.identifier.urihttp://hdl.handle.net/10147/303751-
dc.description.abstractAim. To investigate the association between sleep quality and duration with lipid and glycaemic control in Caucasian subjects with type 2 diabetes. Methods. Sleep quality was assessed using the Pittsburgh Sleep Quality Index (PSQI) in 114 type 2 diabetes (T2DM) subjects. Comparisons were made between subjects with different sleep quality and sleep duration. Hierarchical multiple regression analyses were used to determine contributors to metabolic parameters. Results. Subjects with poor sleep quality (PQ; PSQI ≥ 6) had higher systolic blood pressure, glycated haemoglobin, urine albumin : creatinine ratio (UAC), total cholesterol (TC), and triglycerides (TG) (P < 0.05 for all) compared to those with good sleep quality (GQ; PSQI ≤ 5). Long sleep duration (LSD) subjects had higher TC and short sleep duration (SSD) subjects had higher TG compared to those with medium sleep duration. Sleep duration and PSQI score were independent predictors of TC and low-density lipoprotein cholesterol (LDL), contributing to 14.0% and 6.1% of the total variance, respectively. Conclusions. In this Caucasian T2DM population, PQ is associated with adverse cardiovascular risk markers, and long and short sleep disruptions have an independent negative impact on lipids. Sleep assessment should be included as part of a diabetes clinic review.en_GB
dc.language.isoenen
dc.relation.urlhttp://www.hindawi.com/journals/ije/2013/341506/en_GB
dc.rightsArchived with thanks to International journal of endocrinologyen_GB
dc.subjectSLEEP DISORDERen_GB
dc.subjectDIABETESen_GB
dc.titleAssociation between Sleep Disruption and Levels of Lipids in Caucasians with Type 2 Diabetes.en_GB
dc.typeArticleen
dc.contributor.departmentDepartment of Endocrinology and Diabetes, Royal College of Surgeons in Ireland, Connolly Hospital, Blanchardstown, Dublin 15, Ireland.en_GB
dc.identifier.journalInternational journal of endocrinologyen_GB
dc.description.fundingNo fundingen
dc.description.provinceLeinsteren
dc.description.peer-reviewpeer-reviewen

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