Profound and persistent painful paclitaxel peripheral neuropathy in a premenopausal patient.

Hdl Handle:
http://hdl.handle.net/10147/302324
Title:
Profound and persistent painful paclitaxel peripheral neuropathy in a premenopausal patient.
Authors:
Quintyne, K I; Mainstone, P; McNamara, B; Boers, P; Wallis, F; Gupta, R K
Affiliation:
Department of Medical Oncology, Mid-Western Cancer Centre, Mid-Western Regional Hospital, Limerick, Ireland. keithi.quintyne@hse.ie
Citation:
Profound and persistent painful paclitaxel peripheral neuropathy in a premenopausal patient. 2011, 2011: BMJ Case Rep
Publisher:
BMJ case reports
Journal:
BMJ case reports
Issue Date:
2011
URI:
http://hdl.handle.net/10147/302324
DOI:
10.1136/bcr.12.2010.3645
PubMed ID:
22696717
Additional Links:
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3091274/pdf/bcr.12.2010.3645.pdf
Abstract:
The authors herein report the case of a 35-year-old woman undergoing adjuvant therapy for node positive breast cancer, who presented with short and rapidly progressive history of bilateral lower limb symptoms of peripheral neuropathy following therapy with paclitaxel. MRI of her neural axis revealed no leptomeningeal enhancement or focal metastatic lesions. Neurophysiological tests favoured toxic sensory axonal polyneuropathy. She remains symptomatic following discontinuation of therapy 20 months ago, and is under review with pain management.
Item Type:
Article
Language:
en
MeSH:
Adult; Antineoplastic Agents, Phytogenic; Brain; Breast Neoplasms; Female; Humans; Magnetic Resonance Imaging; Neuroimaging; Paclitaxel; Peripheral Nervous System Diseases
ISSN:
1757-790X

Full metadata record

DC FieldValue Language
dc.contributor.authorQuintyne, K Ien_GB
dc.contributor.authorMainstone, Pen_GB
dc.contributor.authorMcNamara, Ben_GB
dc.contributor.authorBoers, Pen_GB
dc.contributor.authorWallis, Fen_GB
dc.contributor.authorGupta, R Ken_GB
dc.date.accessioned2013-09-26T14:03:30Z-
dc.date.available2013-09-26T14:03:30Z-
dc.date.issued2011-
dc.identifier.citationProfound and persistent painful paclitaxel peripheral neuropathy in a premenopausal patient. 2011, 2011: BMJ Case Repen_GB
dc.identifier.issn1757-790X-
dc.identifier.pmid22696717-
dc.identifier.doi10.1136/bcr.12.2010.3645-
dc.identifier.urihttp://hdl.handle.net/10147/302324-
dc.description.abstractThe authors herein report the case of a 35-year-old woman undergoing adjuvant therapy for node positive breast cancer, who presented with short and rapidly progressive history of bilateral lower limb symptoms of peripheral neuropathy following therapy with paclitaxel. MRI of her neural axis revealed no leptomeningeal enhancement or focal metastatic lesions. Neurophysiological tests favoured toxic sensory axonal polyneuropathy. She remains symptomatic following discontinuation of therapy 20 months ago, and is under review with pain management.en_GB
dc.language.isoenen
dc.publisherBMJ case reportsen_GB
dc.relation.urlhttp://www.ncbi.nlm.nih.gov/pmc/articles/PMC3091274/pdf/bcr.12.2010.3645.pdfen_GB
dc.rightsArchived with thanks to BMJ case reportsen_GB
dc.subject.meshAdult-
dc.subject.meshAntineoplastic Agents, Phytogenic-
dc.subject.meshBrain-
dc.subject.meshBreast Neoplasms-
dc.subject.meshFemale-
dc.subject.meshHumans-
dc.subject.meshMagnetic Resonance Imaging-
dc.subject.meshNeuroimaging-
dc.subject.meshPaclitaxel-
dc.subject.meshPeripheral Nervous System Diseases-
dc.titleProfound and persistent painful paclitaxel peripheral neuropathy in a premenopausal patient.en_GB
dc.typeArticleen
dc.contributor.departmentDepartment of Medical Oncology, Mid-Western Cancer Centre, Mid-Western Regional Hospital, Limerick, Ireland. keithi.quintyne@hse.ieen_GB
dc.identifier.journalBMJ case reportsen_GB
dc.description.fundingNo fundingen
dc.description.provinceLeinsteren
dc.description.peer-reviewpeer-reviewen

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