Cardiac transplant in a family pedigree of hypertrophic cardiomyopathy secondary to a mutation in the AMP gene.

Hdl Handle:
http://hdl.handle.net/10147/302016
Title:
Cardiac transplant in a family pedigree of hypertrophic cardiomyopathy secondary to a mutation in the AMP gene.
Authors:
Schofield, Rebecca Sally; McGarry, Katherine; Murphy, Claire Louise; O'Hare, Kevin
Affiliation:
Department of Medicine, Our Ladys Hospital, Co Meath, Ireland.
Citation:
Cardiac transplant in a family pedigree of hypertrophic cardiomyopathy secondary to a mutation in the AMP gene. 2013, 2013: BMJ Case Rep
Journal:
BMJ case reports
Issue Date:
2013
URI:
http://hdl.handle.net/10147/302016
DOI:
10.1136/bcr-2013-009929
PubMed ID:
23997074
Abstract:
The phenotype of this unique condition comprises left ventricular hypertrophy (LVH), accessory pathways, atrial arrhythmia and premature failure of the atrioventricular node. At age 11, his ECG showed marked voltage criteria for LVH but his echocardiography was negative. He declined further screening but was reassessed at 21 years of age. By this time he had developed significant LVH. He had an implantable cardioventer defibrillator (ICD) in 2001. He developed atrial flutter and fibrillation which was initially treated with medical therapy and then radiofrequency ablation.Unfortunately, his condition deteriorated. He was New York Heart Association (NYHA) class 3-4 for most of 2011 and spent the latter part of the year and most of 2012 as an in-patient. An attempt to upgrade his ICD to a cardiac resynchronisation therapy-defibrillator was unsuccessful.In March 2012 he was placed on the transplant waiting list. He received an organ in June. He is now NHYA class 1 and has returned to work part-time.
Item Type:
Article
Language:
en
ISSN:
1757-790X

Full metadata record

DC FieldValue Language
dc.contributor.authorSchofield, Rebecca Sallyen_GB
dc.contributor.authorMcGarry, Katherineen_GB
dc.contributor.authorMurphy, Claire Louiseen_GB
dc.contributor.authorO'Hare, Kevinen_GB
dc.date.accessioned2013-09-20T15:35:38Z-
dc.date.available2013-09-20T15:35:38Z-
dc.date.issued2013-
dc.identifier.citationCardiac transplant in a family pedigree of hypertrophic cardiomyopathy secondary to a mutation in the AMP gene. 2013, 2013: BMJ Case Repen_GB
dc.identifier.issn1757-790X-
dc.identifier.pmid23997074-
dc.identifier.doi10.1136/bcr-2013-009929-
dc.identifier.urihttp://hdl.handle.net/10147/302016-
dc.description.abstractThe phenotype of this unique condition comprises left ventricular hypertrophy (LVH), accessory pathways, atrial arrhythmia and premature failure of the atrioventricular node. At age 11, his ECG showed marked voltage criteria for LVH but his echocardiography was negative. He declined further screening but was reassessed at 21 years of age. By this time he had developed significant LVH. He had an implantable cardioventer defibrillator (ICD) in 2001. He developed atrial flutter and fibrillation which was initially treated with medical therapy and then radiofrequency ablation.Unfortunately, his condition deteriorated. He was New York Heart Association (NYHA) class 3-4 for most of 2011 and spent the latter part of the year and most of 2012 as an in-patient. An attempt to upgrade his ICD to a cardiac resynchronisation therapy-defibrillator was unsuccessful.In March 2012 he was placed on the transplant waiting list. He received an organ in June. He is now NHYA class 1 and has returned to work part-time.-
dc.language.isoenen
dc.rightsArchived with thanks to BMJ case reportsen_GB
dc.titleCardiac transplant in a family pedigree of hypertrophic cardiomyopathy secondary to a mutation in the AMP gene.en_GB
dc.typeArticleen
dc.contributor.departmentDepartment of Medicine, Our Ladys Hospital, Co Meath, Ireland.en_GB
dc.identifier.journalBMJ case reportsen_GB
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