Depression, anxiety and cardiovascular disease: which symptoms are associated with increased risk in community dwelling older adults?

Hdl Handle:
http://hdl.handle.net/10147/300407
Title:
Depression, anxiety and cardiovascular disease: which symptoms are associated with increased risk in community dwelling older adults?
Authors:
Gallagher, Damien; O'Regan, Claire; Savva, George M; Cronin, Hillary; Lawlor, Brian A; Kenny, Rose A
Affiliation:
Cluain Mhuire Mental Health Services, Blackrock, Co. Dublin, Ireland. gallagherdamien@hotmail.com
Citation:
Depression, anxiety and cardiovascular disease: which symptoms are associated with increased risk in community dwelling older adults? 2012, 142 (1-3):132-8 J Affect Disord
Journal:
Journal of affective disorders
Issue Date:
15-Dec-2012
URI:
http://hdl.handle.net/10147/300407
DOI:
10.1016/j.jad.2012.04.012
PubMed ID:
22858218
Abstract:
Depression is a risk factor for Cardiovascular Disease (CVD). It has been reported that somatic symptoms of depression and not cognitive symptoms are associated with increased risk although findings have been inconsistent. Few studies have examined whether co-morbid anxiety confers additive risk.; We conducted a cross sectional analysis of 7872 community dwelling adults aged 50 years and over from The Irish LongituDinal Study on Ageing (TILDA). Depressive and anxiety symptoms were assessed with Center for Epidemiologic Studies Depression (CES-D) scale and the anxiety subscale of the Hospital Anxiety and Depression Scale (HADS-A), respectively. We conducted logistic regression analyses to determine the relationship between depression, anxiety, individual depressive symptoms and CVD. We further determined whether co-morbid anxiety was associated with increased risk.; Seven hundred and thirty eight (9.4%) study participants reported clinically significant depression. Depression was associated with 80% increased risk of CVD following adjustment for cardiovascular risk factors. Individual depressive symptoms most consistently associated with CVD included low mood, sadness, amotivation, fatigue, diminished appetite and concentration difficulties. Anxiety was associated with increased risk of CVD but did not confer additive risk in participants with depression.; Cross sectional design.; Core symptoms of depression, which are both cognitive and somatic in nature, are associated with increased risk of CVD while co-morbid anxiety did not confer additive risk. It is important that clinicians give due regard both to both cognitive and somatic symptoms of depression when determining cardiovascular risk. Future longitudinal investigation should confirm these findings and explore potential pathological mechanisms.
Item Type:
Article
Language:
en
Description:
BACKGROUND: Depression is a risk factor for Cardiovascular Disease (CVD). It has been reported that somatic symptoms of depression and not cognitive symptoms are associated with increased risk although findings have been inconsistent. Few studies have examined whether co-morbid anxiety confers additive risk. METHODS: We conducted a cross sectional analysis of 7872 community dwelling adults aged 50 years and over from The Irish LongituDinal Study on Ageing (TILDA). Depressive and anxiety symptoms were assessed with Center for Epidemiologic Studies Depression (CES-D) scale and the anxiety subscale of the Hospital Anxiety and Depression Scale (HADS-A), respectively. We conducted logistic regression analyses to determine the relationship between depression, anxiety, individual depressive symptoms and CVD. We further determined whether co-morbid anxiety was associated with increased risk. RESULTS: Seven hundred and thirty eight (9.4%) study participants reported clinically significant depression. Depression was associated with 80% increased risk of CVD following adjustment for cardiovascular risk factors. Individual depressive symptoms most consistently associated with CVD included low mood, sadness, amotivation, fatigue, diminished appetite and concentration difficulties. Anxiety was associated with increased risk of CVD but did not confer additive risk in participants with depression. LIMITATIONS: Cross sectional design. CONCLUSION: Core symptoms of depression, which are both cognitive and somatic in nature, are associated with increased risk of CVD while co-morbid anxiety did not confer additive risk. It is important that clinicians give due regard both to both cognitive and somatic symptoms of depression when determining cardiovascular risk. Future longitudinal investigation should confirm these findings and explore potential pathological mechanisms.
Keywords:
MENTAL AND BEHAVIOURAL DISORDER; CARDIOVASCULAR DISEASE
MeSH:
Aged; Aged, 80 and over; Anxiety; Cardiovascular Diseases; Comorbidity; Cross-Sectional Studies; Depression; Factor Analysis, Statistical; Female; Humans; Ireland; Longitudinal Studies; Male; Middle Aged; Questionnaires; Risk Factors
ISSN:
1573-2517

Full metadata record

DC FieldValue Language
dc.contributor.authorGallagher, Damienen_GB
dc.contributor.authorO'Regan, Claireen_GB
dc.contributor.authorSavva, George Men_GB
dc.contributor.authorCronin, Hillaryen_GB
dc.contributor.authorLawlor, Brian Aen_GB
dc.contributor.authorKenny, Rose Aen_GB
dc.date.accessioned2013-08-30T10:36:52Z-
dc.date.available2013-08-30T10:36:52Z-
dc.date.issued2012-12-15-
dc.identifier.citationDepression, anxiety and cardiovascular disease: which symptoms are associated with increased risk in community dwelling older adults? 2012, 142 (1-3):132-8 J Affect Disorden_GB
dc.identifier.issn1573-2517-
dc.identifier.pmid22858218-
dc.identifier.doi10.1016/j.jad.2012.04.012-
dc.identifier.urihttp://hdl.handle.net/10147/300407-
dc.descriptionBACKGROUND: Depression is a risk factor for Cardiovascular Disease (CVD). It has been reported that somatic symptoms of depression and not cognitive symptoms are associated with increased risk although findings have been inconsistent. Few studies have examined whether co-morbid anxiety confers additive risk. METHODS: We conducted a cross sectional analysis of 7872 community dwelling adults aged 50 years and over from The Irish LongituDinal Study on Ageing (TILDA). Depressive and anxiety symptoms were assessed with Center for Epidemiologic Studies Depression (CES-D) scale and the anxiety subscale of the Hospital Anxiety and Depression Scale (HADS-A), respectively. We conducted logistic regression analyses to determine the relationship between depression, anxiety, individual depressive symptoms and CVD. We further determined whether co-morbid anxiety was associated with increased risk. RESULTS: Seven hundred and thirty eight (9.4%) study participants reported clinically significant depression. Depression was associated with 80% increased risk of CVD following adjustment for cardiovascular risk factors. Individual depressive symptoms most consistently associated with CVD included low mood, sadness, amotivation, fatigue, diminished appetite and concentration difficulties. Anxiety was associated with increased risk of CVD but did not confer additive risk in participants with depression. LIMITATIONS: Cross sectional design. CONCLUSION: Core symptoms of depression, which are both cognitive and somatic in nature, are associated with increased risk of CVD while co-morbid anxiety did not confer additive risk. It is important that clinicians give due regard both to both cognitive and somatic symptoms of depression when determining cardiovascular risk. Future longitudinal investigation should confirm these findings and explore potential pathological mechanisms.en_GB
dc.description.abstractDepression is a risk factor for Cardiovascular Disease (CVD). It has been reported that somatic symptoms of depression and not cognitive symptoms are associated with increased risk although findings have been inconsistent. Few studies have examined whether co-morbid anxiety confers additive risk.-
dc.description.abstractWe conducted a cross sectional analysis of 7872 community dwelling adults aged 50 years and over from The Irish LongituDinal Study on Ageing (TILDA). Depressive and anxiety symptoms were assessed with Center for Epidemiologic Studies Depression (CES-D) scale and the anxiety subscale of the Hospital Anxiety and Depression Scale (HADS-A), respectively. We conducted logistic regression analyses to determine the relationship between depression, anxiety, individual depressive symptoms and CVD. We further determined whether co-morbid anxiety was associated with increased risk.-
dc.description.abstractSeven hundred and thirty eight (9.4%) study participants reported clinically significant depression. Depression was associated with 80% increased risk of CVD following adjustment for cardiovascular risk factors. Individual depressive symptoms most consistently associated with CVD included low mood, sadness, amotivation, fatigue, diminished appetite and concentration difficulties. Anxiety was associated with increased risk of CVD but did not confer additive risk in participants with depression.-
dc.description.abstractCross sectional design.-
dc.description.abstractCore symptoms of depression, which are both cognitive and somatic in nature, are associated with increased risk of CVD while co-morbid anxiety did not confer additive risk. It is important that clinicians give due regard both to both cognitive and somatic symptoms of depression when determining cardiovascular risk. Future longitudinal investigation should confirm these findings and explore potential pathological mechanisms.-
dc.language.isoenen
dc.rightsArchived with thanks to Journal of affective disordersen_GB
dc.subjectMENTAL AND BEHAVIOURAL DISORDERen_GB
dc.subjectCARDIOVASCULAR DISEASEen_GB
dc.subject.meshAged-
dc.subject.meshAged, 80 and over-
dc.subject.meshAnxiety-
dc.subject.meshCardiovascular Diseases-
dc.subject.meshComorbidity-
dc.subject.meshCross-Sectional Studies-
dc.subject.meshDepression-
dc.subject.meshFactor Analysis, Statistical-
dc.subject.meshFemale-
dc.subject.meshHumans-
dc.subject.meshIreland-
dc.subject.meshLongitudinal Studies-
dc.subject.meshMale-
dc.subject.meshMiddle Aged-
dc.subject.meshQuestionnaires-
dc.subject.meshRisk Factors-
dc.titleDepression, anxiety and cardiovascular disease: which symptoms are associated with increased risk in community dwelling older adults?en_GB
dc.typeArticleen
dc.contributor.departmentCluain Mhuire Mental Health Services, Blackrock, Co. Dublin, Ireland. gallagherdamien@hotmail.comen_GB
dc.identifier.journalJournal of affective disordersen_GB

Related articles on PubMed

All Items in Lenus, The Irish Health Repository are protected by copyright, with all rights reserved, unless otherwise indicated.