Paediatric HIV: The experience in Ireland 2004-2011

Hdl Handle:
http://hdl.handle.net/10147/299851
Title:
Paediatric HIV: The experience in Ireland 2004-2011
Authors:
Al-Assaf, N; O Maoldomhnaigh, C; Gavin, P; Butler, K
Publisher:
Irish Medical Journal (IMJ)
Journal:
Irish Medical Journal (IMJ)
Issue Date:
Jul-2013
URI:
http://hdl.handle.net/10147/299851
Abstract:
Despite effective prevention strategies paediatric HIV infection remains an important condition in Ireland. To characterise presentation and identify barriers to optimal management a retrospective chart review of HIV-infected children presenting in Ireland, 2004-2011 was undertaken. Forty-two HIV-infected children were identified; (25 male). Median age at presentation was 6 years (range 0-16 years). 38 children (90%) were born to African mothers. Eleven (26%) were born in Ireland. Twenty-five (59%) were late diagnoses; 11 were symptomatic. Ten of 12 foreign born HIV-infected children had antiretroviral exposure with frequent resistance associated mutations. Seven of 8 children with stage C disease had previously been admitted to hospital in Ireland before diagnosis. Maternal non-adherence to recommendations and seroconversion in pregnancy challenge the goal of paediatric HIV eradication. Targeted strategies for women at risk of infection in pregnancy are required. Late HIV diagnosis remains common, highlighting the need for a more proactive approach to HIV testing.
Item Type:
Article
Language:
en
Keywords:
HIV INFECTION; CHILD

Full metadata record

DC FieldValue Language
dc.contributor.authorAl-Assaf, Nen_GB
dc.contributor.authorO Maoldomhnaigh, Cen_GB
dc.contributor.authorGavin, Pen_GB
dc.contributor.authorButler, Ken_GB
dc.date.accessioned2013-08-26T13:32:44Z-
dc.date.available2013-08-26T13:32:44Z-
dc.date.issued2013-07-
dc.identifier.urihttp://hdl.handle.net/10147/299851-
dc.description.abstractDespite effective prevention strategies paediatric HIV infection remains an important condition in Ireland. To characterise presentation and identify barriers to optimal management a retrospective chart review of HIV-infected children presenting in Ireland, 2004-2011 was undertaken. Forty-two HIV-infected children were identified; (25 male). Median age at presentation was 6 years (range 0-16 years). 38 children (90%) were born to African mothers. Eleven (26%) were born in Ireland. Twenty-five (59%) were late diagnoses; 11 were symptomatic. Ten of 12 foreign born HIV-infected children had antiretroviral exposure with frequent resistance associated mutations. Seven of 8 children with stage C disease had previously been admitted to hospital in Ireland before diagnosis. Maternal non-adherence to recommendations and seroconversion in pregnancy challenge the goal of paediatric HIV eradication. Targeted strategies for women at risk of infection in pregnancy are required. Late HIV diagnosis remains common, highlighting the need for a more proactive approach to HIV testing.en_GB
dc.language.isoenen
dc.publisherIrish Medical Journal (IMJ)en_GB
dc.subjectHIV INFECTIONen_GB
dc.subjectCHILDen_GB
dc.titlePaediatric HIV: The experience in Ireland 2004-2011en_GB
dc.typeArticleen
dc.identifier.journalIrish Medical Journal (IMJ)en_GB
dc.description.fundingNo fundingen
dc.description.provinceLeinsteren
dc.description.peer-reviewpeer-reviewen
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