Tissue Doppler Imaging Quantifies Early Changes in Preterm Myocardium

Hdl Handle:
http://hdl.handle.net/10147/299242
Title:
Tissue Doppler Imaging Quantifies Early Changes in Preterm Myocardium
Authors:
Armstrong, K; Molloy, E; Franklin, O
Publisher:
Archives of Disease in Childhood
Journal:
Archives of Disease in Childhood
Issue Date:
Oct-2012
URI:
http://hdl.handle.net/10147/299242
Additional Links:
Arch Dis Child 2012;97:A321 doi:10.1136/archdischild-2012-302724.1120
Abstract:
Abstract Introduction Haemodynamic changes occurring during the fetal – neonatal transition may impact on global myocardial function in the first week of life. Tissue Doppler imaging (TDI) offers a novel technique to measure changes in systolic and diastolic function in neonates. Aims To use TDI to assess myocardial function in preterm infants compared to gold standard measures. Methods Preterm infants < 32 weeks gestation were recruited. Echocardiography was carried out by a single observer (KA) using the GE Vivid I, on Day 1, 3–4 and Day 7. Clinical parameters were recorded at time of echocardiogram. Standard M mode echocardiography was used to determine shortening and ejection fraction. Myocardial velocities were obtained using a pulsed wave doppler sample from the lateral mitral/tricuspid annuli and intraventricular septum from an apical four chamber view. Peak systolic (S’), early diastolic (E’) and late diastolic (A’) velocities were recorded. Results 140 echocardiograms were performed on 60 neonates with structurally normal hearts. Gestational age range-23+ 6–31+ 6 weeks. There was a significant increase in heart rate (p=0.002)and systolic blood pressure over the 1st week. (p=0.001). There was an increase in myocardial velocities across all measurements, with right ventricular early systolic and late diastolic velocities increasing significantly (p<0.002). There was a significant increase in the left ventricle late diastolic velocities (p=0.036). There was no significant difference in shortening/ejection fraction over the first week. Conclusion TDI offers a reliable measure of myocardial velocities over the first week. Current gold standard measures shortening/ejection fraction showed no significant change in myocardial contractility however TDI demonstrated significant changes in both RV and LV systolic and diastolic velocities.
Item Type:
Conference Poster
Language:
en
Keywords:
PREGNANCY

Full metadata record

DC FieldValue Language
dc.contributor.authorArmstrong, Ken_GB
dc.contributor.authorMolloy, Een_GB
dc.contributor.authorFranklin, Oen_GB
dc.date.accessioned2013-08-20T09:44:18Z-
dc.date.available2013-08-20T09:44:18Z-
dc.date.issued2012-10-
dc.identifier.urihttp://hdl.handle.net/10147/299242-
dc.description.abstractAbstract Introduction Haemodynamic changes occurring during the fetal – neonatal transition may impact on global myocardial function in the first week of life. Tissue Doppler imaging (TDI) offers a novel technique to measure changes in systolic and diastolic function in neonates. Aims To use TDI to assess myocardial function in preterm infants compared to gold standard measures. Methods Preterm infants < 32 weeks gestation were recruited. Echocardiography was carried out by a single observer (KA) using the GE Vivid I, on Day 1, 3–4 and Day 7. Clinical parameters were recorded at time of echocardiogram. Standard M mode echocardiography was used to determine shortening and ejection fraction. Myocardial velocities were obtained using a pulsed wave doppler sample from the lateral mitral/tricuspid annuli and intraventricular septum from an apical four chamber view. Peak systolic (S’), early diastolic (E’) and late diastolic (A’) velocities were recorded. Results 140 echocardiograms were performed on 60 neonates with structurally normal hearts. Gestational age range-23+ 6–31+ 6 weeks. There was a significant increase in heart rate (p=0.002)and systolic blood pressure over the 1st week. (p=0.001). There was an increase in myocardial velocities across all measurements, with right ventricular early systolic and late diastolic velocities increasing significantly (p<0.002). There was a significant increase in the left ventricle late diastolic velocities (p=0.036). There was no significant difference in shortening/ejection fraction over the first week. Conclusion TDI offers a reliable measure of myocardial velocities over the first week. Current gold standard measures shortening/ejection fraction showed no significant change in myocardial contractility however TDI demonstrated significant changes in both RV and LV systolic and diastolic velocities.en_GB
dc.language.isoenen
dc.publisherArchives of Disease in Childhooden_GB
dc.relation.urlArch Dis Child 2012;97:A321 doi:10.1136/archdischild-2012-302724.1120en_GB
dc.subjectPREGNANCYen_GB
dc.titleTissue Doppler Imaging Quantifies Early Changes in Preterm Myocardiumen_GB
dc.typeConference Posteren
dc.identifier.journalArchives of Disease in Childhooden_GB
dc.description.fundingNo fundingen
dc.description.provinceLeinsteren
dc.description.peer-reviewpeer-reviewen
All Items in Lenus, The Irish Health Repository are protected by copyright, with all rights reserved, unless otherwise indicated.