Affiliation
Department of Medical Oncology, Our Lady of Lourdes Hospital, Drogheda, Co. Louth, Ireland. bernadettebrady@gmail.comIssue Date
2013-06MeSH
AdultFemale
Humans
Lung
Lymph Nodes
Lymphoma
Male
Middle Aged
Sarcoidosis
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Dual diagnosis of sarcoidosis and lymphoma. 2013, 182 (2):283-6 Ir J Med SciJournal
Irish journal of medical scienceDOI
10.1007/s11845-012-0854-1PubMed ID
22983882Abstract
Sarcoidosis is a multisystem granulomatous disease of unknown origin with pulmonary and extrapulmonary manifestations. Worldwide it is most often diagnosed in the third and fourth decades and most often affects Swedish, Danish and black patients. The association between malignancy and sarcoidosis has not been conclusively proven. Cancer can eventually occur in patients who have an established diagnosis of sarcoidosis for example, in sarcoidosis-lymphoma syndrome. Sarcoidosis can also subsequently develop in an oncology patient. There are multiple obstacles to confirming epidemiologically the linkage between sarcoidosis and malignancy. Histological verification and clinical acumen are needed to avoid misdiagnosis. The 18 fluorodeoxyglucose (18-FDG) PET has failed to provide a non invasive diagnostic method to differentiate neoplasia from benign sarcoid lesions and tissue diagnosis is essential before commencing a new therapeutic intervention in patients with lymphoma.Item Type
ArticleLanguage
enISSN
1863-4362ae974a485f413a2113503eed53cd6c53
10.1007/s11845-012-0854-1
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