Leucocyte esterase in the rapid diagnosis of paediatric septic arthritis.

Hdl Handle:
http://hdl.handle.net/10147/296786
Title:
Leucocyte esterase in the rapid diagnosis of paediatric septic arthritis.
Authors:
Kelly, E G; Cashman, J P
Affiliation:
Dept. of Trauma and Orthopaedic Surgery, Children's University Hospital, Temple St., Dublin, Ireland. endagkelly@gmail.com
Citation:
Leucocyte esterase in the rapid diagnosis of paediatric septic arthritis. 2013, 80 (2):191-3 Med. Hypotheses
Journal:
Medical hypotheses
Issue Date:
Feb-2013
URI:
http://hdl.handle.net/10147/296786
DOI:
10.1016/j.mehy.2012.11.026
PubMed ID:
23257651
Abstract:
Septic arthritis may affect any age group but is more common in the paediatric population. Infection is generally bacterial in nature. Prompt diagnosis is crucial, as delayed treatment is associated with lifelong joint dysfunction. A clinical history and application of Kocher's criteria may indicate that there is a septic arthritis. However, definitive diagnosis is made on culture of septic synovial fluid. The culture process can take over 24h for the initial culture to yield bacterial colonies. Leucocyte esterase is released by leucocytes at the site of an infection. We hypothesise that leucocyte esterase can be utilized in the rapid diagnosis of septic arthritis and shorten the time to decisive treatment whilst simultaneously decreasing unnecessary treatment of non-septic joints.
Item Type:
Article
Language:
en
MeSH:
Arthritis, Infectious; Carboxylic Ester Hydrolases; Child; Humans; Models, Biological; Synovial Fluid; Time Factors
ISSN:
1532-2777

Full metadata record

DC FieldValue Language
dc.contributor.authorKelly, E Gen_GB
dc.contributor.authorCashman, J Pen_GB
dc.date.accessioned2013-07-22T13:27:23Z-
dc.date.available2013-07-22T13:27:23Z-
dc.date.issued2013-02-
dc.identifier.citationLeucocyte esterase in the rapid diagnosis of paediatric septic arthritis. 2013, 80 (2):191-3 Med. Hypothesesen_GB
dc.identifier.issn1532-2777-
dc.identifier.pmid23257651-
dc.identifier.doi10.1016/j.mehy.2012.11.026-
dc.identifier.urihttp://hdl.handle.net/10147/296786-
dc.description.abstractSeptic arthritis may affect any age group but is more common in the paediatric population. Infection is generally bacterial in nature. Prompt diagnosis is crucial, as delayed treatment is associated with lifelong joint dysfunction. A clinical history and application of Kocher's criteria may indicate that there is a septic arthritis. However, definitive diagnosis is made on culture of septic synovial fluid. The culture process can take over 24h for the initial culture to yield bacterial colonies. Leucocyte esterase is released by leucocytes at the site of an infection. We hypothesise that leucocyte esterase can be utilized in the rapid diagnosis of septic arthritis and shorten the time to decisive treatment whilst simultaneously decreasing unnecessary treatment of non-septic joints.en_GB
dc.language.isoenen
dc.rightsArchived with thanks to Medical hypothesesen_GB
dc.subject.meshArthritis, Infectious-
dc.subject.meshCarboxylic Ester Hydrolases-
dc.subject.meshChild-
dc.subject.meshHumans-
dc.subject.meshModels, Biological-
dc.subject.meshSynovial Fluid-
dc.subject.meshTime Factors-
dc.titleLeucocyte esterase in the rapid diagnosis of paediatric septic arthritis.en_GB
dc.typeArticleen
dc.contributor.departmentDept. of Trauma and Orthopaedic Surgery, Children's University Hospital, Temple St., Dublin, Ireland. endagkelly@gmail.comen_GB
dc.identifier.journalMedical hypothesesen_GB
dc.description.fundingNo fundingen
dc.description.provinceLeinsteren
dc.description.peer-reviewpeer-reviewen

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