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Affiliation
Department of Medical Oncology, Our Lady of Lourdes Hospital, Drogheda, Ireland. dsskamel@hotmail.comIssue Date
2012-11MeSH
AnimalsBreast Neoplasms
Female
Humans
Individualized Medicine
Neoplasm Proteins
Predictive Value of Tests
Prognosis
Proteomics
Tumor Markers, Biological
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Show full item recordCitation
Proteomic classification of breast cancer. 2012, 13 (12):1495-509 Curr Drug TargetsJournal
Current drug targetsPubMed ID
22974393Abstract
Being a significant health problem that affects patients in various age groups, breast cancer has been extensively studied to date. Recently, molecular breast cancer classification has advanced significantly with the availability of genomic profiling technologies. Proteomic technologies have also advanced from traditional protein assays including enzyme-linked immunosorbent assay, immunoblotting and immunohistochemistry to more comprehensive approaches including mass spectrometry and reverse phase protein lysate arrays (RPPA). The purpose of this manuscript is to review the current protein markers that influence breast cancer prediction and prognosis and to focus on novel advances in proteomic classification of breast cancer.Item Type
ArticleLanguage
enISSN
1873-5592Collections
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