Non-pulmonary chronic diseases in adults with Cystic Fibrosis: Analysis of data from the cystic fibrosis registry

Hdl Handle:
http://hdl.handle.net/10147/294587
Title:
Non-pulmonary chronic diseases in adults with Cystic Fibrosis: Analysis of data from the cystic fibrosis registry
Authors:
Somerville, R; Jackson, A; Zhou, S; Fletcher, G; Fitzpatrick, P
Publisher:
Irish Medical Journal
Journal:
Irish Medical Journal
Issue Date:
Jun-2013
URI:
http://hdl.handle.net/10147/294587
Additional Links:
http://www.imj.ie/
Item Type:
Article
Language:
en
Description:
The international literature shows that the demography of cystic fibrosis (CF) is changing, with patients increasingly surviving into adulthood. As they age, patients with CF become more susceptible to specific non-pulmonary chronic diseases. In this study, adult data from the CF Registry of Ireland (CFRI) was used to determine the prevalence and associated features of these diseases. 104 (25.7%) adults had diabetes versus 13 (2.9%) children (p<0.001). Liver disease was present in 47 (11.6%) adults and 26 (5.7%) children (p=0.002). 173 (42.7%) adults had bone disease versus 25 (5.5%) children (p<0.001). Adults with one non-pulmonary chronic disease, for example liver disease, were more likely to have another (p=0.002), those with diabetes and bone disease had a higher number of hospital admissions in the last 12 months (p<0.001 for both) and higher rates of depression (p=0.046 and p=0.049, respectively). These results highlight a number of challenges for the Irish healthcare system.
Keywords:
CYSTIC FIBROSIS; EPIDEMIOLOGY; DATA COLLECTION; DATA ANALYSIS

Full metadata record

DC FieldValue Language
dc.contributor.authorSomerville, Ren_GB
dc.contributor.authorJackson, Aen_GB
dc.contributor.authorZhou, Sen_GB
dc.contributor.authorFletcher, Gen_GB
dc.contributor.authorFitzpatrick, Pen_GB
dc.date.accessioned2013-06-26T09:04:41Z-
dc.date.available2013-06-26T09:04:41Z-
dc.date.issued2013-06-
dc.identifier.urihttp://hdl.handle.net/10147/294587-
dc.descriptionThe international literature shows that the demography of cystic fibrosis (CF) is changing, with patients increasingly surviving into adulthood. As they age, patients with CF become more susceptible to specific non-pulmonary chronic diseases. In this study, adult data from the CF Registry of Ireland (CFRI) was used to determine the prevalence and associated features of these diseases. 104 (25.7%) adults had diabetes versus 13 (2.9%) children (p<0.001). Liver disease was present in 47 (11.6%) adults and 26 (5.7%) children (p=0.002). 173 (42.7%) adults had bone disease versus 25 (5.5%) children (p<0.001). Adults with one non-pulmonary chronic disease, for example liver disease, were more likely to have another (p=0.002), those with diabetes and bone disease had a higher number of hospital admissions in the last 12 months (p<0.001 for both) and higher rates of depression (p=0.046 and p=0.049, respectively). These results highlight a number of challenges for the Irish healthcare system.en_GB
dc.language.isoenen
dc.publisherIrish Medical Journalen_GB
dc.relation.urlhttp://www.imj.ie/en_GB
dc.subjectCYSTIC FIBROSISen_GB
dc.subjectEPIDEMIOLOGYen_GB
dc.subjectDATA COLLECTIONen_GB
dc.subjectDATA ANALYSISen_GB
dc.titleNon-pulmonary chronic diseases in adults with Cystic Fibrosis: Analysis of data from the cystic fibrosis registryen_GB
dc.typeArticleen
dc.identifier.journalIrish Medical Journalen_GB
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