Presentation and management of gastrointestinal stromal tumours

Hdl Handle:
http://hdl.handle.net/10147/294145
Title:
Presentation and management of gastrointestinal stromal tumours
Authors:
Mongan, AM; Malik, V; Rowley, S; Claxton, Z; Muldoon, C; O’Toole, D; Ravi, N; Reynolds, JV
Publisher:
Irish Medical Journal
Journal:
Irish Medical Journal
Issue Date:
Jun-2013
URI:
http://hdl.handle.net/10147/294145
Abstract:
Gastrointestinal stromal tumour (GIST) is the most common mesenchymal tumour of the gastrointestinal tract. The aim of this study was to present the experience of a single centre. A prospective GIST database from 1997 to 2011 in a tertiary referral centre was reviewed. 78 patients (36 male/42 female) with a median age of 66 (range 10-93) were diagnosed with GIST during this period. Surgery was the primary treatment for 70 patients (90%); 19 (24%) resections were laparoscopic. Nineteen patients (24%) received Imatinib therapy. At a median follow up of 3 years, 10 patients (15%) had recurrence. Five-year survival was 89%. Surgery remains the mainstay of treatment. Minimally invasive approaches may be carried out with high cure rates. This study highlights the changing presentation and treatment approach, as well as the excellent outcomes achievable for GIST tumours.
Item Type:
Article
Language:
en
Keywords:
STOMACH CANCER

Full metadata record

DC FieldValue Language
dc.contributor.authorMongan, AMen_GB
dc.contributor.authorMalik, Ven_GB
dc.contributor.authorRowley, Sen_GB
dc.contributor.authorClaxton, Zen_GB
dc.contributor.authorMuldoon, Cen_GB
dc.contributor.authorO’Toole, Den_GB
dc.contributor.authorRavi, Nen_GB
dc.contributor.authorReynolds, JVen_GB
dc.date.accessioned2013-06-18T10:25:54Z-
dc.date.available2013-06-18T10:25:54Z-
dc.date.issued2013-06-
dc.identifier.urihttp://hdl.handle.net/10147/294145-
dc.description.abstractGastrointestinal stromal tumour (GIST) is the most common mesenchymal tumour of the gastrointestinal tract. The aim of this study was to present the experience of a single centre. A prospective GIST database from 1997 to 2011 in a tertiary referral centre was reviewed. 78 patients (36 male/42 female) with a median age of 66 (range 10-93) were diagnosed with GIST during this period. Surgery was the primary treatment for 70 patients (90%); 19 (24%) resections were laparoscopic. Nineteen patients (24%) received Imatinib therapy. At a median follow up of 3 years, 10 patients (15%) had recurrence. Five-year survival was 89%. Surgery remains the mainstay of treatment. Minimally invasive approaches may be carried out with high cure rates. This study highlights the changing presentation and treatment approach, as well as the excellent outcomes achievable for GIST tumours.en_GB
dc.language.isoenen
dc.publisherIrish Medical Journalen_GB
dc.subjectSTOMACH CANCER-
dc.titlePresentation and management of gastrointestinal stromal tumoursen_GB
dc.typeArticleen
dc.identifier.journalIrish Medical Journalen_GB
dc.description.provinceLeinsteren
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