Contrast-induced acute kidney injury: how much contrast is safe?

Hdl Handle:
http://hdl.handle.net/10147/270981
Title:
Contrast-induced acute kidney injury: how much contrast is safe?
Authors:
Keaney, John J; Hannon, Claire M; Murray, Patrick T
Affiliation:
1Department of Cardiology, Mater Misericordiae University Hospital, Dublin, Ireland.
Citation:
Contrast-induced acute kidney injury: how much contrast is safe? 2013: Nephrol. Dial. Transplant.
Journal:
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association
Issue Date:
14-Feb-2013
URI:
http://hdl.handle.net/10147/270981
DOI:
10.1093/ndt/gfs602
PubMed ID:
23413087
Additional Links:
http://ndt.oxfordjournals.org/content/early/2013/02/12/ndt.gfs602.long
Abstract:
Iodinated contrast media (CM) are used in many investigations that a patient may undergo during the course of an in-patient stay. For the vast majority of patients, exposure to CM has no sequelae; however, in a small percentage, it can result in a worsening in renal function termed contrast-induced acute kidney injury (CI-AKI). CI-AKI is one of the leading causes of in-hospital renal dysfunction. It is associated with a significant increase in morbidity and mortality as well as an increased length of hospital stay and costs. Unfortunately, the results of extensive research into pharmacological inventions to prevent CI-AKI remain disappointing. In this article, we briefly outline the pathophysiological mechanisms by which iodinated CM may cause CI-AKI and discuss the evidence for reducing CI-AKI by limiting contrast volumes. In particular, we review the data surrounding the use of contrast volume to glomerular filtration rate ratios, which can be used by clinicians to effectively lower the incidence of CI-AKI in their patients.
Item Type:
Article
Language:
en
ISSN:
1460-2385

Full metadata record

DC FieldValue Language
dc.contributor.authorKeaney, John Jen_GB
dc.contributor.authorHannon, Claire Men_GB
dc.contributor.authorMurray, Patrick Ten_GB
dc.date.accessioned2013-03-04T16:42:24Z-
dc.date.available2013-03-04T16:42:24Z-
dc.date.issued2013-02-14-
dc.identifier.citationContrast-induced acute kidney injury: how much contrast is safe? 2013: Nephrol. Dial. Transplant.en_GB
dc.identifier.issn1460-2385-
dc.identifier.pmid23413087-
dc.identifier.doi10.1093/ndt/gfs602-
dc.identifier.urihttp://hdl.handle.net/10147/270981-
dc.description.abstractIodinated contrast media (CM) are used in many investigations that a patient may undergo during the course of an in-patient stay. For the vast majority of patients, exposure to CM has no sequelae; however, in a small percentage, it can result in a worsening in renal function termed contrast-induced acute kidney injury (CI-AKI). CI-AKI is one of the leading causes of in-hospital renal dysfunction. It is associated with a significant increase in morbidity and mortality as well as an increased length of hospital stay and costs. Unfortunately, the results of extensive research into pharmacological inventions to prevent CI-AKI remain disappointing. In this article, we briefly outline the pathophysiological mechanisms by which iodinated CM may cause CI-AKI and discuss the evidence for reducing CI-AKI by limiting contrast volumes. In particular, we review the data surrounding the use of contrast volume to glomerular filtration rate ratios, which can be used by clinicians to effectively lower the incidence of CI-AKI in their patients.en_GB
dc.languageENG-
dc.language.isoenen
dc.relation.urlhttp://ndt.oxfordjournals.org/content/early/2013/02/12/ndt.gfs602.longen_GB
dc.rightsArchived with thanks to Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Associationen_GB
dc.titleContrast-induced acute kidney injury: how much contrast is safe?en_GB
dc.typeArticleen
dc.contributor.department1Department of Cardiology, Mater Misericordiae University Hospital, Dublin, Ireland.en_GB
dc.identifier.journalNephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Associationen_GB
dc.description.provinceLeinsteren

Related articles on PubMed

All Items in Lenus, The Irish Health Repository are protected by copyright, with all rights reserved, unless otherwise indicated.