Chemotherapy for resistant or recurrent gestational trophoblastic neoplasia.

Hdl Handle:
http://hdl.handle.net/10147/270372
Title:
Chemotherapy for resistant or recurrent gestational trophoblastic neoplasia.
Authors:
Alazzam, Mo'iad; Tidy, John; Osborne, Raymond; Coleman, Robert; Hancock, Barry W; Lawrie, Theresa A
Affiliation:
Department of Gynaecology, The Galway Clinic, Doughiska, Galway, Ireland. moiad@doctors.org.uk
Citation:
Chemotherapy for resistant or recurrent gestational trophoblastic neoplasia. 2012, 12:CD008891 Cochrane Database Syst Rev
Journal:
Cochrane database of systematic reviews (Online)
Issue Date:
Dec-2012
URI:
http://hdl.handle.net/10147/270372
DOI:
10.1002/14651858.CD008891.pub2
PubMed ID:
23235667
Additional Links:
http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD008891.pub2/pdf
Abstract:
Gestational trophoblastic neoplasia (GTN) is a highly curable group of pregnancy-related tumours; however, approximately 25% of GTN tumours will be resistant to, or will relapse after, initial chemotherapy. These resistant and relapsed lesions will require salvage chemotherapy with or without surgery. Various salvage regimens are used worldwide. It is unclear which regimens are the most effective and the least toxic.
Item Type:
Systematic Review
Language:
en
MeSH:
Drug Resistance, Neoplasm; Female; Gestational Trophoblastic Disease; Humans; Neoplasm Recurrence, Local; Pregnancy
ISSN:
1469-493X

Full metadata record

DC FieldValue Language
dc.contributor.authorAlazzam, Mo'iaden_GB
dc.contributor.authorTidy, Johnen_GB
dc.contributor.authorOsborne, Raymonden_GB
dc.contributor.authorColeman, Roberten_GB
dc.contributor.authorHancock, Barry Wen_GB
dc.contributor.authorLawrie, Theresa Aen_GB
dc.date.accessioned2013-02-25T14:24:01Z-
dc.date.available2013-02-25T14:24:01Z-
dc.date.issued2012-12-
dc.identifier.citationChemotherapy for resistant or recurrent gestational trophoblastic neoplasia. 2012, 12:CD008891 Cochrane Database Syst Reven_GB
dc.identifier.issn1469-493X-
dc.identifier.pmid23235667-
dc.identifier.doi10.1002/14651858.CD008891.pub2-
dc.identifier.urihttp://hdl.handle.net/10147/270372-
dc.description.abstractGestational trophoblastic neoplasia (GTN) is a highly curable group of pregnancy-related tumours; however, approximately 25% of GTN tumours will be resistant to, or will relapse after, initial chemotherapy. These resistant and relapsed lesions will require salvage chemotherapy with or without surgery. Various salvage regimens are used worldwide. It is unclear which regimens are the most effective and the least toxic.en_GB
dc.language.isoenen
dc.relation.urlhttp://onlinelibrary.wiley.com/doi/10.1002/14651858.CD008891.pub2/pdfen_GB
dc.rightsArchived with thanks to Cochrane database of systematic reviews (Online)en_GB
dc.subject.meshDrug Resistance, Neoplasm-
dc.subject.meshFemale-
dc.subject.meshGestational Trophoblastic Disease-
dc.subject.meshHumans-
dc.subject.meshNeoplasm Recurrence, Local-
dc.subject.meshPregnancy-
dc.titleChemotherapy for resistant or recurrent gestational trophoblastic neoplasia.en_GB
dc.typeSystematic Reviewen
dc.contributor.departmentDepartment of Gynaecology, The Galway Clinic, Doughiska, Galway, Ireland. moiad@doctors.org.uken_GB
dc.identifier.journalCochrane database of systematic reviews (Online)en_GB
dc.description.provinceConnachten

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