Prevalence of item level negative symptoms in first episode psychosis diagnoses.

Hdl Handle:
http://hdl.handle.net/10147/265455
Title:
Prevalence of item level negative symptoms in first episode psychosis diagnoses.
Authors:
Lyne, John; O'Donoghue, Brian; Owens, Elizabeth; Renwick, Laoise; Madigan, Kevin; Kinsella, Anthony; Clarke, Mary; Turner, Niall; O'Callaghan, Eadbhard
Affiliation:
DETECT Services, Avila House, Block 5 Blackrock Business Park, Blackrock, Co Dublin, Ireland. johnlyne@mail.com
Citation:
Prevalence of item level negative symptoms in first episode psychosis diagnoses. 2012, 135 (1-3):128-33 Schizophr. Res.
Journal:
Schizophrenia research
Issue Date:
Mar-2012
URI:
http://hdl.handle.net/10147/265455
DOI:
10.1016/j.schres.2012.01.004
PubMed ID:
22281102
Abstract:
The relevance of negative symptoms across the diagnostic spectrum of the psychoses remains uncertain. The purpose of this study was to report on prevalence of item and subscale level negative symptoms across the first episode psychosis (FEP) diagnostic spectrum in an epidemiological sample, and to ascertain whether items and subscales were more prevalent in a schizophrenia spectrum diagnoses group compared to an 'all other psychotic diagnoses' group. We measured negative symptoms in 330 patients presenting with FEP using the Scale for Assessment of Negative Symptoms (SANS), and ascertained diagnosis using the Structured Clinical Interview for DSM IV. Prevalence of SANS items and subscales were tabulated across all psychotic diagnoses, and logistic regression analysis determined which items and subscales were predictive of schizophrenia spectrum diagnoses. SANS items were most prevalent in schizophrenia spectrum conditions but frequently presented in other FEP diagnoses, particularly substance induced psychotic disorder and Major Depressive Disorder. Brief psychotic disorder and bipolar disorders had low levels of negative symptoms. SANS items and subscales which significantly predicted schizophrenia spectrum diagnoses, were also frequently present in some of the other psychotic diagnoses. Conclusions: SANS items have high prevalence in FEP, and while commonest in schizophrenia spectrum conditions are not restricted to this diagnostic subgroup.
Item Type:
Article
Language:
en
Description:
The relevance of negative symptoms across the diagnostic spectrum of the psychoses remains uncertain. The purpose of this study was to report on prevalence of item and subscale level negative symptoms across the first episode psychosis (FEP) diagnostic spectrum in an epidemiological sample, and to ascertain whether items and subscales were more prevalent in a schizophrenia spectrum diagnoses group compared to an 'all other psychotic diagnoses' group. We measured negative symptoms in 330 patients presenting with FEP using the Scale for Assessment of Negative Symptoms (SANS), and ascertained diagnosis using the Structured Clinical Interview for DSM IV. Prevalence of SANS items and subscales were tabulated across all psychotic diagnoses, and logistic regression analysis determined which items and subscales were predictive of schizophrenia spectrum diagnoses. SANS items were most prevalent in schizophrenia spectrum conditions but frequently presented in other FEP diagnoses, particularly substance induced psychotic disorder and Major Depressive Disorder. Brief psychotic disorder and bipolar disorders had low levels of negative symptoms. SANS items and subscales which significantly predicted schizophrenia spectrum diagnoses, were also frequently present in some of the other psychotic diagnoses. Conclusions: SANS items have high prevalence in FEP, and while commonest in schizophrenia spectrum conditions are not restricted to this diagnostic subgroup.
Keywords:
BIPOLAR DISORDER; DIAGNOSIS; EPIDEMIOLOGY; DEPRESSIVE DISORDER; PSYCHIATRIC STATUS RATING SCALES; PSYCHOTIC DISORDERS; PSYCHOSIS; SCHIZOPHRENIA; IRELAND; PREVALENCE
MeSH:
Adolescent; Adult; Aged; Bipolar Disorder; Depressive Disorder, Major; Female; Humans; Ireland; Male; Middle Aged; Prevalence; Psychiatric Status Rating Scales; Psychotic Disorders; Retrospective Studies; Schizophrenia; Schizophrenia, Paranoid; Severity of Illness Index; Young Adult
ISSN:
1573-2509

Full metadata record

DC FieldValue Language
dc.contributor.authorLyne, Johnen_GB
dc.contributor.authorO'Donoghue, Brianen_GB
dc.contributor.authorOwens, Elizabethen_GB
dc.contributor.authorRenwick, Laoiseen_GB
dc.contributor.authorMadigan, Kevinen_GB
dc.contributor.authorKinsella, Anthonyen_GB
dc.contributor.authorClarke, Maryen_GB
dc.contributor.authorTurner, Niallen_GB
dc.contributor.authorO'Callaghan, Eadbharden_GB
dc.date.accessioned2013-01-15T11:40:53Z-
dc.date.available2013-01-15T11:40:53Z-
dc.date.issued2012-03-
dc.identifier.citationPrevalence of item level negative symptoms in first episode psychosis diagnoses. 2012, 135 (1-3):128-33 Schizophr. Res.en_GB
dc.identifier.issn1573-2509-
dc.identifier.pmid22281102-
dc.identifier.doi10.1016/j.schres.2012.01.004-
dc.identifier.urihttp://hdl.handle.net/10147/265455-
dc.descriptionThe relevance of negative symptoms across the diagnostic spectrum of the psychoses remains uncertain. The purpose of this study was to report on prevalence of item and subscale level negative symptoms across the first episode psychosis (FEP) diagnostic spectrum in an epidemiological sample, and to ascertain whether items and subscales were more prevalent in a schizophrenia spectrum diagnoses group compared to an 'all other psychotic diagnoses' group. We measured negative symptoms in 330 patients presenting with FEP using the Scale for Assessment of Negative Symptoms (SANS), and ascertained diagnosis using the Structured Clinical Interview for DSM IV. Prevalence of SANS items and subscales were tabulated across all psychotic diagnoses, and logistic regression analysis determined which items and subscales were predictive of schizophrenia spectrum diagnoses. SANS items were most prevalent in schizophrenia spectrum conditions but frequently presented in other FEP diagnoses, particularly substance induced psychotic disorder and Major Depressive Disorder. Brief psychotic disorder and bipolar disorders had low levels of negative symptoms. SANS items and subscales which significantly predicted schizophrenia spectrum diagnoses, were also frequently present in some of the other psychotic diagnoses. Conclusions: SANS items have high prevalence in FEP, and while commonest in schizophrenia spectrum conditions are not restricted to this diagnostic subgroup.en_GB
dc.description.abstractThe relevance of negative symptoms across the diagnostic spectrum of the psychoses remains uncertain. The purpose of this study was to report on prevalence of item and subscale level negative symptoms across the first episode psychosis (FEP) diagnostic spectrum in an epidemiological sample, and to ascertain whether items and subscales were more prevalent in a schizophrenia spectrum diagnoses group compared to an 'all other psychotic diagnoses' group. We measured negative symptoms in 330 patients presenting with FEP using the Scale for Assessment of Negative Symptoms (SANS), and ascertained diagnosis using the Structured Clinical Interview for DSM IV. Prevalence of SANS items and subscales were tabulated across all psychotic diagnoses, and logistic regression analysis determined which items and subscales were predictive of schizophrenia spectrum diagnoses. SANS items were most prevalent in schizophrenia spectrum conditions but frequently presented in other FEP diagnoses, particularly substance induced psychotic disorder and Major Depressive Disorder. Brief psychotic disorder and bipolar disorders had low levels of negative symptoms. SANS items and subscales which significantly predicted schizophrenia spectrum diagnoses, were also frequently present in some of the other psychotic diagnoses. Conclusions: SANS items have high prevalence in FEP, and while commonest in schizophrenia spectrum conditions are not restricted to this diagnostic subgroup.-
dc.language.isoenen
dc.rightsArchived with thanks to Schizophrenia researchen_GB
dc.subjectBIPOLAR DISORDERen_GB
dc.subjectDIAGNOSISen_GB
dc.subjectEPIDEMIOLOGYen_GB
dc.subjectDEPRESSIVE DISORDERen_GB
dc.subjectPSYCHIATRIC STATUS RATING SCALESen_GB
dc.subjectPSYCHOTIC DISORDERSen_GB
dc.subjectPSYCHOSISen_GB
dc.subjectSCHIZOPHRENIAen_GB
dc.subjectIRELANDen_GB
dc.subjectPREVALENCEen_GB
dc.subject.meshAdolescent-
dc.subject.meshAdult-
dc.subject.meshAged-
dc.subject.meshBipolar Disorder-
dc.subject.meshDepressive Disorder, Major-
dc.subject.meshFemale-
dc.subject.meshHumans-
dc.subject.meshIreland-
dc.subject.meshMale-
dc.subject.meshMiddle Aged-
dc.subject.meshPrevalence-
dc.subject.meshPsychiatric Status Rating Scales-
dc.subject.meshPsychotic Disorders-
dc.subject.meshRetrospective Studies-
dc.subject.meshSchizophrenia-
dc.subject.meshSchizophrenia, Paranoid-
dc.subject.meshSeverity of Illness Index-
dc.subject.meshYoung Adult-
dc.titlePrevalence of item level negative symptoms in first episode psychosis diagnoses.en_GB
dc.typeArticleen
dc.contributor.departmentDETECT Services, Avila House, Block 5 Blackrock Business Park, Blackrock, Co Dublin, Ireland. johnlyne@mail.comen_GB
dc.identifier.journalSchizophrenia researchen_GB

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