HLA associations reveal genetic heterogeneity in psoriatic arthritis and in the psoriasis phenotype.

Hdl Handle:
http://hdl.handle.net/10147/254739
Title:
HLA associations reveal genetic heterogeneity in psoriatic arthritis and in the psoriasis phenotype.
Authors:
Winchester, Robert; Minevich, Gregory; Steshenko, Valeria; Kirby, Brian; Kane, David; Greenberg, David A; FitzGerald, Oliver
Affiliation:
Columbia University, New York, New York 10032, USA. rjw8@columbia.edu
Citation:
HLA associations reveal genetic heterogeneity in psoriatic arthritis and in the psoriasis phenotype. 2012, 64 (4):1134-44 Arthritis Rheum.
Publisher:
Arthritis and rheumatism
Journal:
Arthritis and rheumatism
Issue Date:
Apr-2012
URI:
http://hdl.handle.net/10147/254739
DOI:
10.1002/art.33415
PubMed ID:
22006066
Abstract:
Rigorously ascertained cases of psoriatic arthritis in subjects presenting to a rheumatology unit were compared with cases of psoriasis in subjects presenting to a dermatology unit, where subjects with musculoskeletal features were excluded, to address 1) the extent to which the contribution of the major histocompatibility complex (MHC) to psoriatic arthritis susceptibility resembles that in psoriasis, and 2) whether MHC genes determine quantitative traits within the psoriatic arthritis phenotype.
Item Type:
Article
Language:
en
MeSH:
Adult; Alleles; Arthritis, Psoriatic; Disease Progression; Genetic Association Studies; Genetic Heterogeneity; Genetic Predisposition to Disease; Genotype; HLA Antigens; Haplotypes; Humans; Phenotype; Psoriasis
ISSN:
1529-0131

Full metadata record

DC FieldValue Language
dc.contributor.authorWinchester, Roberten_GB
dc.contributor.authorMinevich, Gregoryen_GB
dc.contributor.authorSteshenko, Valeriaen_GB
dc.contributor.authorKirby, Brianen_GB
dc.contributor.authorKane, Daviden_GB
dc.contributor.authorGreenberg, David Aen_GB
dc.contributor.authorFitzGerald, Oliveren_GB
dc.date.accessioned2012-12-06T10:20:48Z-
dc.date.available2012-12-06T10:20:48Z-
dc.date.issued2012-04-
dc.identifier.citationHLA associations reveal genetic heterogeneity in psoriatic arthritis and in the psoriasis phenotype. 2012, 64 (4):1134-44 Arthritis Rheum.en_GB
dc.identifier.issn1529-0131-
dc.identifier.pmid22006066-
dc.identifier.doi10.1002/art.33415-
dc.identifier.urihttp://hdl.handle.net/10147/254739-
dc.description.abstractRigorously ascertained cases of psoriatic arthritis in subjects presenting to a rheumatology unit were compared with cases of psoriasis in subjects presenting to a dermatology unit, where subjects with musculoskeletal features were excluded, to address 1) the extent to which the contribution of the major histocompatibility complex (MHC) to psoriatic arthritis susceptibility resembles that in psoriasis, and 2) whether MHC genes determine quantitative traits within the psoriatic arthritis phenotype.en_GB
dc.language.isoenen
dc.publisherArthritis and rheumatismen_GB
dc.rightsArchived with thanks to Arthritis and rheumatismen_GB
dc.subject.meshAdult-
dc.subject.meshAlleles-
dc.subject.meshArthritis, Psoriatic-
dc.subject.meshDisease Progression-
dc.subject.meshGenetic Association Studies-
dc.subject.meshGenetic Heterogeneity-
dc.subject.meshGenetic Predisposition to Disease-
dc.subject.meshGenotype-
dc.subject.meshHLA Antigens-
dc.subject.meshHaplotypes-
dc.subject.meshHumans-
dc.subject.meshPhenotype-
dc.subject.meshPsoriasis-
dc.titleHLA associations reveal genetic heterogeneity in psoriatic arthritis and in the psoriasis phenotype.en_GB
dc.typeArticleen
dc.contributor.departmentColumbia University, New York, New York 10032, USA. rjw8@columbia.eduen_GB
dc.identifier.journalArthritis and rheumatismen_GB
dc.description.provinceLeinsteren

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