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ACTH deficiency, higher doses of hydrocortisone replacement, and radiotherapy are independent predictors of mortality in patients with acromegaly.
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|Title: ||ACTH deficiency, higher doses of hydrocortisone replacement, and radiotherapy are independent predictors of mortality in patients with acromegaly.|
|Affiliation: ||Centre for Endocrinology, School of Clinical and Experimental Medicine, College of Medical and Dental Sciences, University of Birmingham, Birmingham B15 2TH, United Kingdom.|
|Citation: ||ACTH deficiency, higher doses of hydrocortisone replacement, and radiotherapy are independent predictors of mortality in patients with acromegaly. 2009, 94 (11):4216-23 J. Clin. Endocrinol. Metab.|
|Publisher: ||The Journal of clinical endocrinology and metabolism|
|Journal: ||The Journal of clinical endocrinology and metabolism|
|Issue Date: ||Nov-2009 |
|PubMed ID: ||19808848|
|Abstract: ||A number of retrospective studies report that patients with acromegaly have increased morbidity and premature mortality, with standardized mortality ratios (SMR) of 1.3-3. Many patients with acromegaly develop hypopituitarism as a result of the pituitary adenoma itself or therapies such as surgery and radiotherapy. Pituitary radiotherapy and hypopituitarism have also been associated with an increased SMR.|
Cause of Death
Hormone Replacement Therapy
Predictive Value of Tests
Respiratory Tract Diseases
|Appears in Collections: ||Adelaide Meath Hospital Tallaght|
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