Immune profile and Epstein-Barr virus infection in acute interstitial nephritis: an immunohistochemical study in 78 patients.

Hdl Handle:
http://hdl.handle.net/10147/253863
Title:
Immune profile and Epstein-Barr virus infection in acute interstitial nephritis: an immunohistochemical study in 78 patients.
Authors:
Mansur, Abdurrezagh; Little, Mark A; Oh, Weng Chin; Jacques, Steven; Nightingale, Peter; Howie, Alexander J; Savage, Caroline O S
Affiliation:
Renal Immunobiology, University of Birmingham, College of Medical and Dental Sciences, London, UK.
Citation:
Immune profile and Epstein-Barr virus infection in acute interstitial nephritis: an immunohistochemical study in 78 patients. 2011, 119 (4):c293-300 Nephron Clin Pract
Publisher:
Nephron. Clinical practice
Journal:
Nephron. Clinical practice
Issue Date:
2011
URI:
http://hdl.handle.net/10147/253863
DOI:
10.1159/000329671
PubMed ID:
21952467
Abstract:
Acute interstitial nephritis (AIN) is a common cause of acute kidney injury and is characterised by a dense interstitial cellular infiltrate, which has not been well defined. Previous studies have demonstrated a correlation between Epstein-Barr virus (EBV) infection and AIN. The purpose of our study was to define the nature of the interstitial immune infiltrate and to investigate the possibility of renal infection with EBV.
Item Type:
Article
Language:
en
MeSH:
Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Chemokine CCL11; Creatinine; Eosinophils; Epstein-Barr Virus Infections; Female; Herpesvirus 4, Human; Humans; Interleukin-4; Kidney; Macrophages; Male; Middle Aged; Nephritis, Interstitial; RNA, Viral; Receptors, CCR3; Receptors, CCR4; Retrospective Studies; Th2 Cells; Vascular Cell Adhesion Molecule-1; Viral Matrix Proteins; Young Adult
ISSN:
1660-2110

Full metadata record

DC FieldValue Language
dc.contributor.authorMansur, Abdurrezaghen_GB
dc.contributor.authorLittle, Mark Aen_GB
dc.contributor.authorOh, Weng Chinen_GB
dc.contributor.authorJacques, Stevenen_GB
dc.contributor.authorNightingale, Peteren_GB
dc.contributor.authorHowie, Alexander Jen_GB
dc.contributor.authorSavage, Caroline O Sen_GB
dc.date.accessioned2012-11-29T12:39:16Z-
dc.date.available2012-11-29T12:39:16Z-
dc.date.issued2011-
dc.identifier.citationImmune profile and Epstein-Barr virus infection in acute interstitial nephritis: an immunohistochemical study in 78 patients. 2011, 119 (4):c293-300 Nephron Clin Practen_GB
dc.identifier.issn1660-2110-
dc.identifier.pmid21952467-
dc.identifier.doi10.1159/000329671-
dc.identifier.urihttp://hdl.handle.net/10147/253863-
dc.description.abstractAcute interstitial nephritis (AIN) is a common cause of acute kidney injury and is characterised by a dense interstitial cellular infiltrate, which has not been well defined. Previous studies have demonstrated a correlation between Epstein-Barr virus (EBV) infection and AIN. The purpose of our study was to define the nature of the interstitial immune infiltrate and to investigate the possibility of renal infection with EBV.en_GB
dc.language.isoenen
dc.publisherNephron. Clinical practiceen_GB
dc.rightsArchived with thanks to Nephron. Clinical practiceen_GB
dc.subject.meshAcute Disease-
dc.subject.meshAdolescent-
dc.subject.meshAdult-
dc.subject.meshAged-
dc.subject.meshAged, 80 and over-
dc.subject.meshAntigens, CD-
dc.subject.meshAntigens, Differentiation, Myelomonocytic-
dc.subject.meshChemokine CCL11-
dc.subject.meshCreatinine-
dc.subject.meshEosinophils-
dc.subject.meshEpstein-Barr Virus Infections-
dc.subject.meshFemale-
dc.subject.meshHerpesvirus 4, Human-
dc.subject.meshHumans-
dc.subject.meshInterleukin-4-
dc.subject.meshKidney-
dc.subject.meshMacrophages-
dc.subject.meshMale-
dc.subject.meshMiddle Aged-
dc.subject.meshNephritis, Interstitial-
dc.subject.meshRNA, Viral-
dc.subject.meshReceptors, CCR3-
dc.subject.meshReceptors, CCR4-
dc.subject.meshRetrospective Studies-
dc.subject.meshTh2 Cells-
dc.subject.meshVascular Cell Adhesion Molecule-1-
dc.subject.meshViral Matrix Proteins-
dc.subject.meshYoung Adult-
dc.titleImmune profile and Epstein-Barr virus infection in acute interstitial nephritis: an immunohistochemical study in 78 patients.en_GB
dc.typeArticleen
dc.contributor.departmentRenal Immunobiology, University of Birmingham, College of Medical and Dental Sciences, London, UK.en_GB
dc.identifier.journalNephron. Clinical practiceen_GB
dc.description.provinceLeinsteren
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