Increased spontaneous apoptosis, but not survivin expression, is associated with histomorphologic response to neoadjuvant chemoradiation in rectal cancer.

Hdl Handle:
http://hdl.handle.net/10147/252785
Title:
Increased spontaneous apoptosis, but not survivin expression, is associated with histomorphologic response to neoadjuvant chemoradiation in rectal cancer.
Authors:
McDowell, Dermot T; Smith, Fraser M; Reynolds, John V; Maher, Stephen G; Adida, Collette; Crotty, Paul; Gaffney, Eoin F; Hollywood, Donal; Mehigan, Brian; Stephens, Richard B; Kennedy, M J
Affiliation:
Department of Academic Surgery, St James's Hospital, Dublin, Ireland.
Citation:
Increased spontaneous apoptosis, but not survivin expression, is associated with histomorphologic response to neoadjuvant chemoradiation in rectal cancer. 2009, 24 (11):1261-9 Int J Colorectal Dis
Publisher:
International journal of colorectal disease
Journal:
International journal of colorectal disease
Issue Date:
Nov-2009
URI:
http://hdl.handle.net/10147/252785
DOI:
10.1007/s00384-009-0755-6
PubMed ID:
19593573
Abstract:
Survivin has been shown to be an important mediator of cellular radioresistance in vitro. This study aims to compare survivin expression and apoptosis to histomorphologic responses to neoadjuvant radiochemotherapy (RCT) in rectal cancer.
Item Type:
Article
Language:
en
MeSH:
Apoptosis; Biopsy; Cell Proliferation; Chemotherapy, Adjuvant; Gene Expression Regulation, Neoplastic; Humans; Inhibitor of Apoptosis Proteins; Ki-67 Antigen; Lymph Nodes; Microtubule-Associated Proteins; Neoadjuvant Therapy; Neoplasm Staging; Radiotherapy, Adjuvant; Rectal Neoplasms; Staining and Labeling
ISSN:
1432-1262

Full metadata record

DC FieldValue Language
dc.contributor.authorMcDowell, Dermot Ten_GB
dc.contributor.authorSmith, Fraser Men_GB
dc.contributor.authorReynolds, John Ven_GB
dc.contributor.authorMaher, Stephen Gen_GB
dc.contributor.authorAdida, Colletteen_GB
dc.contributor.authorCrotty, Paulen_GB
dc.contributor.authorGaffney, Eoin Fen_GB
dc.contributor.authorHollywood, Donalen_GB
dc.contributor.authorMehigan, Brianen_GB
dc.contributor.authorStephens, Richard Ben_GB
dc.contributor.authorKennedy, M Jen_GB
dc.date.accessioned2012-11-20T16:45:53Z-
dc.date.available2012-11-20T16:45:53Z-
dc.date.issued2009-11-
dc.identifier.citationIncreased spontaneous apoptosis, but not survivin expression, is associated with histomorphologic response to neoadjuvant chemoradiation in rectal cancer. 2009, 24 (11):1261-9 Int J Colorectal Disen_GB
dc.identifier.issn1432-1262-
dc.identifier.pmid19593573-
dc.identifier.doi10.1007/s00384-009-0755-6-
dc.identifier.urihttp://hdl.handle.net/10147/252785-
dc.description.abstractSurvivin has been shown to be an important mediator of cellular radioresistance in vitro. This study aims to compare survivin expression and apoptosis to histomorphologic responses to neoadjuvant radiochemotherapy (RCT) in rectal cancer.en_GB
dc.language.isoenen
dc.publisherInternational journal of colorectal diseaseen_GB
dc.rightsArchived with thanks to International journal of colorectal diseaseen_GB
dc.subject.meshApoptosis-
dc.subject.meshBiopsy-
dc.subject.meshCell Proliferation-
dc.subject.meshChemotherapy, Adjuvant-
dc.subject.meshGene Expression Regulation, Neoplastic-
dc.subject.meshHumans-
dc.subject.meshInhibitor of Apoptosis Proteins-
dc.subject.meshKi-67 Antigen-
dc.subject.meshLymph Nodes-
dc.subject.meshMicrotubule-Associated Proteins-
dc.subject.meshNeoadjuvant Therapy-
dc.subject.meshNeoplasm Staging-
dc.subject.meshRadiotherapy, Adjuvant-
dc.subject.meshRectal Neoplasms-
dc.subject.meshStaining and Labeling-
dc.titleIncreased spontaneous apoptosis, but not survivin expression, is associated with histomorphologic response to neoadjuvant chemoradiation in rectal cancer.en_GB
dc.typeArticleen
dc.contributor.departmentDepartment of Academic Surgery, St James's Hospital, Dublin, Ireland.en_GB
dc.identifier.journalInternational journal of colorectal diseaseen_GB
dc.description.provinceLeinsteren

Related articles on PubMed

All Items in Lenus, The Irish Health Repository are protected by copyright, with all rights reserved, unless otherwise indicated.