Relationship between reaction time, fine motor control, and visual-spatial perception on vigilance and visual-motor tasks in 22q11.2 Deletion Syndrome.

Hdl Handle:
http://hdl.handle.net/10147/248751
Title:
Relationship between reaction time, fine motor control, and visual-spatial perception on vigilance and visual-motor tasks in 22q11.2 Deletion Syndrome.
Authors:
Howley, Sarah A; Prasad, Sarah E; Pender, Niall P; Murphy, Kieran C
Affiliation:
Department of Psychiatry, Royal College of Surgeons in Ireland, Education and Research Centre, Beaumont Hospital, Dublin 9, Ireland. sarah.howley.10@ucl.ac.uk
Citation:
Relationship between reaction time, fine motor control, and visual-spatial perception on vigilance and visual-motor tasks in 22q11.2 Deletion Syndrome., 33 (5):1495-502 Res Dev Disabil
Journal:
Research in developmental disabilities
Issue Date:
15-Oct-2012
URI:
http://hdl.handle.net/10147/248751
DOI:
10.1016/j.ridd.2012.03.023
PubMed ID:
22522207
Additional Links:
http://www.sciencedirect.com/science/article/pii/S0891422212000789
Abstract:
22q11.2 Deletion Syndrome (22q11DS) is a common microdeletion disorder associated with mild to moderate intellectual disability and specific neurocognitive deficits, particularly in visual-motor and attentional abilities. Currently there is evidence that the visual-motor profile of 22q11DS is not entirely mediated by intellectual disability and that these individuals have specific deficits in visual-motor integration. However, the extent to which attentional deficits, such as vigilance, influence impairments on visual motor tasks in 22q11DS is unclear. This study examines visual-motor abilities and reaction time using a range of standardised tests in 35 children with 22q11DS, 26 age-matched typically developing (TD) sibling controls and 17 low-IQ community controls. Statistically significant deficits were observed in the 22q11DS group compared to both low-IQ and TD control groups on a timed fine motor control and accuracy task. The 22q11DS group performed significantly better than the low-IQ control group on an untimed drawing task and were equivalent to the TD control group on point accuracy and simple reaction time tests. Results suggest that visual motor deficits in 22q11DS are primarily attributable to deficits in psychomotor speed which becomes apparent when tasks are timed versus untimed. Moreover, the integration of visual and motor information may be intact and, indeed, represent a relative strength in 22q11DS when there are no time constraints imposed. While this may have significant implications for cognitive remediation strategies for children with 22q11DS, the relationship between reaction time, visual reasoning, cognitive complexity, fine motor speed and accuracy, and graphomotor ability on visual-motor tasks is still unclear.
Item Type:
Article
Language:
en
MeSH:
Adolescent; Arousal; Child; Cognition; DiGeorge Syndrome; Female; Humans; Intellectual Disability; Intelligence; Male; Motor Skills; Neuropsychological Tests; Psychomotor Performance; Reaction Time; Space Perception
ISSN:
1873-3379

Full metadata record

DC FieldValue Language
dc.contributor.authorHowley, Sarah Aen_GB
dc.contributor.authorPrasad, Sarah Een_GB
dc.contributor.authorPender, Niall Pen_GB
dc.contributor.authorMurphy, Kieran Cen_GB
dc.date.accessioned2012-10-15T08:12:47Z-
dc.date.available2012-10-15T08:12:47Z-
dc.date.issued2012-10-15-
dc.identifier.citationRelationship between reaction time, fine motor control, and visual-spatial perception on vigilance and visual-motor tasks in 22q11.2 Deletion Syndrome., 33 (5):1495-502 Res Dev Disabilen_GB
dc.identifier.issn1873-3379-
dc.identifier.pmid22522207-
dc.identifier.doi10.1016/j.ridd.2012.03.023-
dc.identifier.urihttp://hdl.handle.net/10147/248751-
dc.description.abstract22q11.2 Deletion Syndrome (22q11DS) is a common microdeletion disorder associated with mild to moderate intellectual disability and specific neurocognitive deficits, particularly in visual-motor and attentional abilities. Currently there is evidence that the visual-motor profile of 22q11DS is not entirely mediated by intellectual disability and that these individuals have specific deficits in visual-motor integration. However, the extent to which attentional deficits, such as vigilance, influence impairments on visual motor tasks in 22q11DS is unclear. This study examines visual-motor abilities and reaction time using a range of standardised tests in 35 children with 22q11DS, 26 age-matched typically developing (TD) sibling controls and 17 low-IQ community controls. Statistically significant deficits were observed in the 22q11DS group compared to both low-IQ and TD control groups on a timed fine motor control and accuracy task. The 22q11DS group performed significantly better than the low-IQ control group on an untimed drawing task and were equivalent to the TD control group on point accuracy and simple reaction time tests. Results suggest that visual motor deficits in 22q11DS are primarily attributable to deficits in psychomotor speed which becomes apparent when tasks are timed versus untimed. Moreover, the integration of visual and motor information may be intact and, indeed, represent a relative strength in 22q11DS when there are no time constraints imposed. While this may have significant implications for cognitive remediation strategies for children with 22q11DS, the relationship between reaction time, visual reasoning, cognitive complexity, fine motor speed and accuracy, and graphomotor ability on visual-motor tasks is still unclear.en_GB
dc.language.isoenen
dc.relation.urlhttp://www.sciencedirect.com/science/article/pii/S0891422212000789en_GB
dc.rightsArchived with thanks to Research in developmental disabilitiesen_GB
dc.subject.meshAdolescent-
dc.subject.meshArousal-
dc.subject.meshChild-
dc.subject.meshCognition-
dc.subject.meshDiGeorge Syndrome-
dc.subject.meshFemale-
dc.subject.meshHumans-
dc.subject.meshIntellectual Disability-
dc.subject.meshIntelligence-
dc.subject.meshMale-
dc.subject.meshMotor Skills-
dc.subject.meshNeuropsychological Tests-
dc.subject.meshPsychomotor Performance-
dc.subject.meshReaction Time-
dc.subject.meshSpace Perception-
dc.titleRelationship between reaction time, fine motor control, and visual-spatial perception on vigilance and visual-motor tasks in 22q11.2 Deletion Syndrome.en_GB
dc.typeArticleen
dc.contributor.departmentDepartment of Psychiatry, Royal College of Surgeons in Ireland, Education and Research Centre, Beaumont Hospital, Dublin 9, Ireland. sarah.howley.10@ucl.ac.uken_GB
dc.identifier.journalResearch in developmental disabilitiesen_GB
dc.description.provinceLeinsteren

Related articles on PubMed

All Items in Lenus, The Irish Health Repository are protected by copyright, with all rights reserved, unless otherwise indicated.