Allelic expression imbalance of the schizophrenia susceptibility gene CHI3L1: evidence of cis-acting variation and tissue specific regulation.

Hdl Handle:
http://hdl.handle.net/10147/238798
Title:
Allelic expression imbalance of the schizophrenia susceptibility gene CHI3L1: evidence of cis-acting variation and tissue specific regulation.
Authors:
Hill, Matthew James; Kenny, Elaine; Roche, Siobhan; Morris, Derek W; Corvin, Aiden; Hawi, Ziarih; Gill, Michael; Anney, Richard J L
Affiliation:
Neuropsychiatric Genetics Research Group, Trinity College Dublin, Institute of Molecular Medicine, Ireland. matthew.hill@kcl.ac.uk
Citation:
Allelic expression imbalance of the schizophrenia susceptibility gene CHI3L1: evidence of cis-acting variation and tissue specific regulation. 2011, 21 (6):281-6 Psychiatr. Genet.
Journal:
Psychiatric genetics
Issue Date:
Dec-2011
URI:
http://hdl.handle.net/10147/238798
DOI:
10.1097/YPG.0b013e328348045b
PubMed ID:
21642896
Abstract:
To identify cis-acting regulatory variants influencing the expression of the schizophrenia susceptibility gene chitinase 3-like 1 gene (CHI3L1) in human lymphoblasts and post-mortem brain tissue.
Item Type:
Article
Language:
en
MeSH:
Adipokines; Alleles; Allelic Imbalance; Brain; Gene Expression Regulation; Genetic Predisposition to Disease; HapMap Project; Humans; Lectins; Linkage Disequilibrium; Lymphocytes; Organ Specificity; Polymorphism, Single Nucleotide; Postmortem Changes; Promoter Regions, Genetic; RNA, Messenger; Schizophrenia
ISSN:
1473-5873

Full metadata record

DC FieldValue Language
dc.contributor.authorHill, Matthew Jamesen_GB
dc.contributor.authorKenny, Elaineen_GB
dc.contributor.authorRoche, Siobhanen_GB
dc.contributor.authorMorris, Derek Wen_GB
dc.contributor.authorCorvin, Aidenen_GB
dc.contributor.authorHawi, Ziarihen_GB
dc.contributor.authorGill, Michaelen_GB
dc.contributor.authorAnney, Richard J Len_GB
dc.date.accessioned2012-08-15T14:13:59Z-
dc.date.available2012-08-15T14:13:59Z-
dc.date.issued2011-12-
dc.identifier.citationAllelic expression imbalance of the schizophrenia susceptibility gene CHI3L1: evidence of cis-acting variation and tissue specific regulation. 2011, 21 (6):281-6 Psychiatr. Genet.en_GB
dc.identifier.issn1473-5873-
dc.identifier.pmid21642896-
dc.identifier.doi10.1097/YPG.0b013e328348045b-
dc.identifier.urihttp://hdl.handle.net/10147/238798-
dc.description.abstractTo identify cis-acting regulatory variants influencing the expression of the schizophrenia susceptibility gene chitinase 3-like 1 gene (CHI3L1) in human lymphoblasts and post-mortem brain tissue.en_GB
dc.language.isoenen
dc.rightsArchived with thanks to Psychiatric geneticsen_GB
dc.subject.meshAdipokines-
dc.subject.meshAlleles-
dc.subject.meshAllelic Imbalance-
dc.subject.meshBrain-
dc.subject.meshGene Expression Regulation-
dc.subject.meshGenetic Predisposition to Disease-
dc.subject.meshHapMap Project-
dc.subject.meshHumans-
dc.subject.meshLectins-
dc.subject.meshLinkage Disequilibrium-
dc.subject.meshLymphocytes-
dc.subject.meshOrgan Specificity-
dc.subject.meshPolymorphism, Single Nucleotide-
dc.subject.meshPostmortem Changes-
dc.subject.meshPromoter Regions, Genetic-
dc.subject.meshRNA, Messenger-
dc.subject.meshSchizophrenia-
dc.titleAllelic expression imbalance of the schizophrenia susceptibility gene CHI3L1: evidence of cis-acting variation and tissue specific regulation.en_GB
dc.typeArticleen
dc.contributor.departmentNeuropsychiatric Genetics Research Group, Trinity College Dublin, Institute of Molecular Medicine, Ireland. matthew.hill@kcl.ac.uken_GB
dc.identifier.journalPsychiatric geneticsen_GB
dc.description.provinceLeinsteren

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