Obstetric outcome with low molecular weight heparin therapy during pregnancy.

2.50
Hdl Handle:
http://hdl.handle.net/10147/233211
Title:
Obstetric outcome with low molecular weight heparin therapy during pregnancy.
Authors:
Donnelly, J; Byrne, J; Murphy, K; McAuliffe, F
Affiliation:
Department of Obstetrics and Gynaecology, National Maternity Hospital, Holles St, Dublin 2. jenniferdonnelly@mac.com
Citation:
Obstetric outcome with low molecular weight heparin therapy during pregnancy. 2012, 105 (1):27-9 Ir Med J
Publisher:
Irish Medical Journal (IMJ)
Journal:
Irish medical journal
Issue Date:
Jan-2012
URI:
http://hdl.handle.net/10147/233211
PubMed ID:
22397211
Additional Links:
http://www.ncbi.nlm.nih.gov/pubmed/22397211
Abstract:
This was a prospective study of women attending a combined haematology/obstetric antenatal clinic in the National Maternity Hospital (2002-2008). Obstetric outcome in mothers treated with low molecular weight heparin (LMWH) was compared to the general obstetric population of 2006. There were 133 pregnancies in 105 women. 85 (63.9%) received prophylactic LMWH and 38 (28.6%) received therapeutic LMWH in pregnancy. 10 (7.5%) received postpartum prophylaxis only. The perinatal mortality rate was 7.6/1000 births. 14 (11.3%) women delivered preterm which is significantly higher than the hospital population rate (5.7%, p<0.05). Despite significantly higher labour induction rates (50% vs 29.2% p<0.01), there was no difference in CS rates compared to the general hospital population (15.4% vs 18.9%, NS). If carefully managed, these high-risk women can achieve similar vaginal delivery rates as the general obstetric population.
Item Type:
Article
Language:
en
MeSH:
Adult; Anticoagulants; Chi-Square Distribution; Female; Heparin, Low-Molecular-Weight; Humans; Ireland; Pregnancy; Pregnancy Complications, Cardiovascular; Pregnancy Outcome; Risk Factors; Venous Thrombosis
ISSN:
0332-3102

Full metadata record

DC FieldValue Language
dc.contributor.authorDonnelly, Jen_GB
dc.contributor.authorByrne, Jen_GB
dc.contributor.authorMurphy, Ken_GB
dc.contributor.authorMcAuliffe, Fen_GB
dc.date.accessioned2012-07-11T13:19:26Z-
dc.date.available2012-07-11T13:19:26Z-
dc.date.issued2012-01-
dc.identifier.citationObstetric outcome with low molecular weight heparin therapy during pregnancy. 2012, 105 (1):27-9 Ir Med Jen_GB
dc.identifier.issn0332-3102-
dc.identifier.pmid22397211-
dc.identifier.urihttp://hdl.handle.net/10147/233211-
dc.description.abstractThis was a prospective study of women attending a combined haematology/obstetric antenatal clinic in the National Maternity Hospital (2002-2008). Obstetric outcome in mothers treated with low molecular weight heparin (LMWH) was compared to the general obstetric population of 2006. There were 133 pregnancies in 105 women. 85 (63.9%) received prophylactic LMWH and 38 (28.6%) received therapeutic LMWH in pregnancy. 10 (7.5%) received postpartum prophylaxis only. The perinatal mortality rate was 7.6/1000 births. 14 (11.3%) women delivered preterm which is significantly higher than the hospital population rate (5.7%, p<0.05). Despite significantly higher labour induction rates (50% vs 29.2% p<0.01), there was no difference in CS rates compared to the general hospital population (15.4% vs 18.9%, NS). If carefully managed, these high-risk women can achieve similar vaginal delivery rates as the general obstetric population.en_GB
dc.language.isoenen
dc.publisherIrish Medical Journal (IMJ)en_GB
dc.relation.urlhttp://www.ncbi.nlm.nih.gov/pubmed/22397211en_GB
dc.rightsArchived with thanks to Irish medical journalen_GB
dc.subject.meshAdult-
dc.subject.meshAnticoagulants-
dc.subject.meshChi-Square Distribution-
dc.subject.meshFemale-
dc.subject.meshHeparin, Low-Molecular-Weight-
dc.subject.meshHumans-
dc.subject.meshIreland-
dc.subject.meshPregnancy-
dc.subject.meshPregnancy Complications, Cardiovascular-
dc.subject.meshPregnancy Outcome-
dc.subject.meshRisk Factors-
dc.subject.meshVenous Thrombosis-
dc.titleObstetric outcome with low molecular weight heparin therapy during pregnancy.en_GB
dc.typeArticleen
dc.contributor.departmentDepartment of Obstetrics and Gynaecology, National Maternity Hospital, Holles St, Dublin 2. jenniferdonnelly@mac.comen_GB
dc.identifier.journalIrish medical journalen_GB
dc.description.provinceLeinsteren

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