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Role of the insulin-like growth factor 1 axis and visceral adiposity in oesophageal adenocarcinoma.

Hdl Handle:
http://hdl.handle.net/10147/231052
Title:
Role of the insulin-like growth factor 1 axis and visceral adiposity in oesophageal adenocarcinoma.
Authors:
Donohoe, C L; Doyle, S L; McGarrigle, S; Cathcart, M C; Daly, E; O'Grady, A; Lysaght, J; Pidgeon, G P; Reynolds, J V
Affiliation:
Department of Surgery, Trinity Centre for Health Sciences, Trinity College Dublin/St James's Hospital, Dublin, Ireland.
Citation:
Role of the insulin-like growth factor 1 axis and visceral adiposity in oesophageal adenocarcinoma. 2012, 99 (3):387-96 Br J Surg
Journal:
The British journal of surgery
Issue Date:
Mar-2012
URI:
http://hdl.handle.net/10147/231052
DOI:
10.1002/bjs.8658
PubMed ID:
22241325
Abstract:
Epidemiological studies have linked obesity with many cancers. The insulin-like growth factor (IGF) 1 axis may be an important mediator in obesity-associated cancer. This study examined the relationship between IGF-1 and its receptor (IGF-1R) in oesophageal adenocarcinoma, a cancer strongly linked to obesity.
Item Type:
Article
Language:
en
MeSH:
Adenocarcinoma; Adult; Aged; Body Mass Index; Enzyme-Linked Immunosorbent Assay; Esophageal Neoplasms; Female; Humans; Immunohistochemistry; Insulin-Like Growth Factor I; Intra-Abdominal Fat; Male; Middle Aged; Obesity, Abdominal; RNA, Messenger; Real-Time Polymerase Chain Reaction; Receptor, IGF Type 1; Survival Analysis; Waist Circumference
ISSN:
1365-2168

Full metadata record

DC FieldValue Language
dc.contributor.authorDonohoe, C Len_GB
dc.contributor.authorDoyle, S Len_GB
dc.contributor.authorMcGarrigle, Sen_GB
dc.contributor.authorCathcart, M Cen_GB
dc.contributor.authorDaly, Een_GB
dc.contributor.authorO'Grady, Aen_GB
dc.contributor.authorLysaght, Jen_GB
dc.contributor.authorPidgeon, G Pen_GB
dc.contributor.authorReynolds, J Ven_GB
dc.date.accessioned2012-06-27T14:39:29Z-
dc.date.available2012-06-27T14:39:29Z-
dc.date.issued2012-03-
dc.identifier.citationRole of the insulin-like growth factor 1 axis and visceral adiposity in oesophageal adenocarcinoma. 2012, 99 (3):387-96 Br J Surgen_GB
dc.identifier.issn1365-2168-
dc.identifier.pmid22241325-
dc.identifier.doi10.1002/bjs.8658-
dc.identifier.urihttp://hdl.handle.net/10147/231052-
dc.description.abstractEpidemiological studies have linked obesity with many cancers. The insulin-like growth factor (IGF) 1 axis may be an important mediator in obesity-associated cancer. This study examined the relationship between IGF-1 and its receptor (IGF-1R) in oesophageal adenocarcinoma, a cancer strongly linked to obesity.en_GB
dc.language.isoenen
dc.rightsArchived with thanks to The British journal of surgeryen_GB
dc.subject.meshAdenocarcinoma-
dc.subject.meshAdult-
dc.subject.meshAged-
dc.subject.meshBody Mass Index-
dc.subject.meshEnzyme-Linked Immunosorbent Assay-
dc.subject.meshEsophageal Neoplasms-
dc.subject.meshFemale-
dc.subject.meshHumans-
dc.subject.meshImmunohistochemistry-
dc.subject.meshInsulin-Like Growth Factor I-
dc.subject.meshIntra-Abdominal Fat-
dc.subject.meshMale-
dc.subject.meshMiddle Aged-
dc.subject.meshObesity, Abdominal-
dc.subject.meshRNA, Messenger-
dc.subject.meshReal-Time Polymerase Chain Reaction-
dc.subject.meshReceptor, IGF Type 1-
dc.subject.meshSurvival Analysis-
dc.subject.meshWaist Circumference-
dc.titleRole of the insulin-like growth factor 1 axis and visceral adiposity in oesophageal adenocarcinoma.en_GB
dc.typeArticleen
dc.contributor.departmentDepartment of Surgery, Trinity Centre for Health Sciences, Trinity College Dublin/St James's Hospital, Dublin, Ireland.en_GB
dc.identifier.journalThe British journal of surgeryen_GB
dc.description.provinceLeinsteren

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