PCR ribotype prevalence and molecular basis of macrolide-lincosamide-streptogramin B (MLSB) and fluoroquinolone resistance in Irish clinical Clostridium difficile isolates.

Hdl Handle:
http://hdl.handle.net/10147/230657
Title:
PCR ribotype prevalence and molecular basis of macrolide-lincosamide-streptogramin B (MLSB) and fluoroquinolone resistance in Irish clinical Clostridium difficile isolates.
Authors:
Solomon, Katie; Fanning, Seamus; McDermott, Sinead; Murray, Sean; Scott, Louise; Martin, Alan; Skally, Mairead; Burns, Karen; Kuijper, Ed; Fitzpatrick, Fidelma; Fenelon, Lynda; Kyne, Lorraine
Affiliation:
School of Public Health, Physiotherapy & Population Science, UCD Veterinary Sciences Centre, University College Dublin, Belfield, Dublin 4, Ireland. katie.solomon@ucd.ie
Citation:
PCR ribotype prevalence and molecular basis of macrolide-lincosamide-streptogramin B (MLSB) and fluoroquinolone resistance in Irish clinical Clostridium difficile isolates. 2011, 66 (9):1976-82 J. Antimicrob. Chemother.
Journal:
The Journal of antimicrobial chemotherapy
Issue Date:
Sep-2011
URI:
http://hdl.handle.net/10147/230657
DOI:
10.1093/jac/dkr275
PubMed ID:
21712239
Abstract:
Antimicrobial use is recognized as a risk factor for Clostridium difficile infection (CDI) and outbreaks. We studied the relationship between PCR ribotype, antimicrobial susceptibility and the genetic basis of resistance in response to exposure to antimicrobial agents.
Item Type:
Article
Language:
en
MeSH:
Amino Acid Substitution; Anti-Bacterial Agents; Bacterial Infections; Clostridium difficile; DNA Gyrase; DNA, Bacterial; Drug Resistance, Bacterial; Enterocolitis, Pseudomembranous; Fluoroquinolones; Humans; Ireland; Lincosamides; Macrolides; Methyltransferases; Microbial Sensitivity Tests; Reverse Transcriptase Polymerase Chain Reaction; Ribotyping; Streptogramin B
ISSN:
1460-2091

Full metadata record

DC FieldValue Language
dc.contributor.authorSolomon, Katieen_GB
dc.contributor.authorFanning, Seamusen_GB
dc.contributor.authorMcDermott, Sineaden_GB
dc.contributor.authorMurray, Seanen_GB
dc.contributor.authorScott, Louiseen_GB
dc.contributor.authorMartin, Alanen_GB
dc.contributor.authorSkally, Maireaden_GB
dc.contributor.authorBurns, Karenen_GB
dc.contributor.authorKuijper, Eden_GB
dc.contributor.authorFitzpatrick, Fidelmaen_GB
dc.contributor.authorFenelon, Lyndaen_GB
dc.contributor.authorKyne, Lorraineen_GB
dc.date.accessioned2012-06-25T16:11:20Z-
dc.date.available2012-06-25T16:11:20Z-
dc.date.issued2011-09-
dc.identifier.citationPCR ribotype prevalence and molecular basis of macrolide-lincosamide-streptogramin B (MLSB) and fluoroquinolone resistance in Irish clinical Clostridium difficile isolates. 2011, 66 (9):1976-82 J. Antimicrob. Chemother.en_GB
dc.identifier.issn1460-2091-
dc.identifier.pmid21712239-
dc.identifier.doi10.1093/jac/dkr275-
dc.identifier.urihttp://hdl.handle.net/10147/230657-
dc.description.abstractAntimicrobial use is recognized as a risk factor for Clostridium difficile infection (CDI) and outbreaks. We studied the relationship between PCR ribotype, antimicrobial susceptibility and the genetic basis of resistance in response to exposure to antimicrobial agents.en_GB
dc.language.isoenen
dc.rightsArchived with thanks to The Journal of antimicrobial chemotherapyen_GB
dc.subject.meshAmino Acid Substitution-
dc.subject.meshAnti-Bacterial Agents-
dc.subject.meshBacterial Infections-
dc.subject.meshClostridium difficile-
dc.subject.meshDNA Gyrase-
dc.subject.meshDNA, Bacterial-
dc.subject.meshDrug Resistance, Bacterial-
dc.subject.meshEnterocolitis, Pseudomembranous-
dc.subject.meshFluoroquinolones-
dc.subject.meshHumans-
dc.subject.meshIreland-
dc.subject.meshLincosamides-
dc.subject.meshMacrolides-
dc.subject.meshMethyltransferases-
dc.subject.meshMicrobial Sensitivity Tests-
dc.subject.meshReverse Transcriptase Polymerase Chain Reaction-
dc.subject.meshRibotyping-
dc.subject.meshStreptogramin B-
dc.titlePCR ribotype prevalence and molecular basis of macrolide-lincosamide-streptogramin B (MLSB) and fluoroquinolone resistance in Irish clinical Clostridium difficile isolates.en_GB
dc.typeArticleen
dc.contributor.departmentSchool of Public Health, Physiotherapy & Population Science, UCD Veterinary Sciences Centre, University College Dublin, Belfield, Dublin 4, Ireland. katie.solomon@ucd.ieen_GB
dc.identifier.journalThe Journal of antimicrobial chemotherapyen_GB
dc.description.provinceLeinsteren

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