Language processing abnormalities in adolescents with psychotic-like experiences: An event related potential study.

Hdl Handle:
http://hdl.handle.net/10147/230453
Title:
Language processing abnormalities in adolescents with psychotic-like experiences: An event related potential study.
Authors:
Murphy, Jennifer; Blanchard, Mathieu M; Rawdon, Caroline; Kavanagh, Fergal; Kelleher, Ian; Clarke, Mary C; Roche, Richard A P; Cannon, Mary
Affiliation:
Department of Psychology, National University of Ireland, Maynooth, Co. Kildare, Ireland; Department of Psychiatry, Royal College of Surgeons in Ireland, Dublin, Ireland.
Citation:
Language processing abnormalities in adolescents with psychotic-like experiences: An event related potential study. 2012, 137 (1-3):91-6 Schizophr. Res.
Journal:
Schizophrenia research
Issue Date:
May-2012
URI:
http://hdl.handle.net/10147/230453
DOI:
10.1016/j.schres.2012.01.017
PubMed ID:
22330177
Abstract:
Language impairments are a well established finding in patients with schizophrenia and in individuals at-risk for psychosis. A growing body of research has revealed shared risk factors between individuals with psychotic-like experiences (PLEs) from the general population and patients with schizophrenia. In particular, adolescents with PLEs have been shown to be at an increased risk for later psychosis. However, to date there has been little information published on electrophysiological correlates of language comprehension in this at-risk group. A 64 channel EEG recorded electrical activity while 37 (16 At-Risk; 21 Controls) participants completed the British Picture Vocabulary Scale (BPVS-II) receptive vocabulary task. The P300 component was examined as a function of language comprehension. The at-risk group were impaired behaviourally on receptive language and were characterised by a reduction in P300 amplitude relative to the control group. The results of this study reveal electrophysiological evidence for receptive language deficits in adolescents with PLEs, suggesting that the earliest neurobiological changes underlying psychosis may be apparent in the adolescent period.
Item Type:
Article
Language:
en
ISSN:
1573-2509

Full metadata record

DC FieldValue Language
dc.contributor.authorMurphy, Jenniferen_GB
dc.contributor.authorBlanchard, Mathieu Men_GB
dc.contributor.authorRawdon, Carolineen_GB
dc.contributor.authorKavanagh, Fergalen_GB
dc.contributor.authorKelleher, Ianen_GB
dc.contributor.authorClarke, Mary Cen_GB
dc.contributor.authorRoche, Richard A Pen_GB
dc.contributor.authorCannon, Maryen_GB
dc.date.accessioned2012-06-25T09:33:10Z-
dc.date.available2012-06-25T09:33:10Z-
dc.date.issued2012-05-
dc.identifier.citationLanguage processing abnormalities in adolescents with psychotic-like experiences: An event related potential study. 2012, 137 (1-3):91-6 Schizophr. Res.en_GB
dc.identifier.issn1573-2509-
dc.identifier.pmid22330177-
dc.identifier.doi10.1016/j.schres.2012.01.017-
dc.identifier.urihttp://hdl.handle.net/10147/230453-
dc.description.abstractLanguage impairments are a well established finding in patients with schizophrenia and in individuals at-risk for psychosis. A growing body of research has revealed shared risk factors between individuals with psychotic-like experiences (PLEs) from the general population and patients with schizophrenia. In particular, adolescents with PLEs have been shown to be at an increased risk for later psychosis. However, to date there has been little information published on electrophysiological correlates of language comprehension in this at-risk group. A 64 channel EEG recorded electrical activity while 37 (16 At-Risk; 21 Controls) participants completed the British Picture Vocabulary Scale (BPVS-II) receptive vocabulary task. The P300 component was examined as a function of language comprehension. The at-risk group were impaired behaviourally on receptive language and were characterised by a reduction in P300 amplitude relative to the control group. The results of this study reveal electrophysiological evidence for receptive language deficits in adolescents with PLEs, suggesting that the earliest neurobiological changes underlying psychosis may be apparent in the adolescent period.en_GB
dc.language.isoenen
dc.rightsArchived with thanks to Schizophrenia researchen_GB
dc.titleLanguage processing abnormalities in adolescents with psychotic-like experiences: An event related potential study.en_GB
dc.typeArticleen
dc.contributor.departmentDepartment of Psychology, National University of Ireland, Maynooth, Co. Kildare, Ireland; Department of Psychiatry, Royal College of Surgeons in Ireland, Dublin, Ireland.en_GB
dc.identifier.journalSchizophrenia researchen_GB
dc.description.provinceLeinsteren

Related articles on PubMed

All Items in Lenus, The Irish Health Repository are protected by copyright, with all rights reserved, unless otherwise indicated.