Genome-wide mapping for clinically relevant predictors of lamotrigine- and phenytoin-induced hypersensitivity reactions.

Hdl Handle:
http://hdl.handle.net/10147/229913
Title:
Genome-wide mapping for clinically relevant predictors of lamotrigine- and phenytoin-induced hypersensitivity reactions.
Authors:
McCormack, Mark; Urban, Thomas J; Shianna, Kevin V; Walley, Nicole; Pandolfo, Massimo; Depondt, Chantal; Chaila, Elijah; O'Conner, Gerard D; Kasperavičiūtė, Dalia; Radtke, Rodney A; Heinzen, Erin L; Sisodiya, Sanjay M; Delanty, Norman; Cavalleri, Gianpiero L
Affiliation:
The Department of Molecular & Cellular Therapeutics, the Royal College of Surgeons in Ireland, Dublin 2, Ireland.
Citation:
Genome-wide mapping for clinically relevant predictors of lamotrigine- and phenytoin-induced hypersensitivity reactions. 2012, 13 (4):399-405 Pharmacogenomics
Journal:
Pharmacogenomics
Issue Date:
Mar-2012
URI:
http://hdl.handle.net/10147/229913
DOI:
10.2217/pgs.11.165
PubMed ID:
22379998
Additional Links:
http://www.futuremedicine.com/doi/pdf/10.2217/pgs.11.165
Abstract:
An association between carbamazepine-induced hypersensitivity and HLA-A*3101 has been reported in populations of both European and Asian descent. We aimed to investigate HLA-A*3101 and other common variants across the genome as markers for cutaneous adverse drug reactions (cADRs) attributed to lamotrigine and phenytoin.
Item Type:
Article
Language:
en
ISSN:
1744-8042

Full metadata record

DC FieldValue Language
dc.contributor.authorMcCormack, Marken_GB
dc.contributor.authorUrban, Thomas Jen_GB
dc.contributor.authorShianna, Kevin Ven_GB
dc.contributor.authorWalley, Nicoleen_GB
dc.contributor.authorPandolfo, Massimoen_GB
dc.contributor.authorDepondt, Chantalen_GB
dc.contributor.authorChaila, Elijahen_GB
dc.contributor.authorO'Conner, Gerard Den_GB
dc.contributor.authorKasperavičiūtė, Daliaen_GB
dc.contributor.authorRadtke, Rodney Aen_GB
dc.contributor.authorHeinzen, Erin Len_GB
dc.contributor.authorSisodiya, Sanjay Men_GB
dc.contributor.authorDelanty, Normanen_GB
dc.contributor.authorCavalleri, Gianpiero Len_GB
dc.date.accessioned2012-06-20T13:46:34Z-
dc.date.available2012-06-20T13:46:34Z-
dc.date.issued2012-03-
dc.identifier.citationGenome-wide mapping for clinically relevant predictors of lamotrigine- and phenytoin-induced hypersensitivity reactions. 2012, 13 (4):399-405 Pharmacogenomicsen_GB
dc.identifier.issn1744-8042-
dc.identifier.pmid22379998-
dc.identifier.doi10.2217/pgs.11.165-
dc.identifier.urihttp://hdl.handle.net/10147/229913-
dc.description.abstractAn association between carbamazepine-induced hypersensitivity and HLA-A*3101 has been reported in populations of both European and Asian descent. We aimed to investigate HLA-A*3101 and other common variants across the genome as markers for cutaneous adverse drug reactions (cADRs) attributed to lamotrigine and phenytoin.en_GB
dc.language.isoenen
dc.relation.urlhttp://www.futuremedicine.com/doi/pdf/10.2217/pgs.11.165en_GB
dc.rightsArchived with thanks to Pharmacogenomicsen_GB
dc.titleGenome-wide mapping for clinically relevant predictors of lamotrigine- and phenytoin-induced hypersensitivity reactions.en_GB
dc.typeArticleen
dc.contributor.departmentThe Department of Molecular & Cellular Therapeutics, the Royal College of Surgeons in Ireland, Dublin 2, Ireland.en_GB
dc.identifier.journalPharmacogenomicsen_GB
dc.description.provinceLeinsteren

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