Disorders of water homeostasis in neurosurgical patients.

Hdl Handle:
http://hdl.handle.net/10147/229192
Title:
Disorders of water homeostasis in neurosurgical patients.
Authors:
Hannon, Mark J; Finucane, Francis M; Sherlock, Mark; Agha, Amar; Thompson, Christopher J
Affiliation:
Academic Department of Endocrinology, Beaumont Hospital, Dublin 9, Ireland. christhompson@beaumont.ie.
Citation:
Disorders of water homeostasis in neurosurgical patients. 2012, 97 (5):1423-33 J. Clin. Endocrinol. Metab.
Journal:
The Journal of clinical endocrinology and metabolism
Issue Date:
May-2012
URI:
http://hdl.handle.net/10147/229192
DOI:
10.1210/jc.2011-3201
PubMed ID:
22362821
Abstract:
Context: Disorders of water balance are common in neurosurgical patients and usually manifest as hypo- or hypernatremia. They are most commonly seen after subarachnoid hemorrhage, traumatic brain injury, with intracranial tumors, and after pituitary surgery. Setting: We reviewed the experience of endocrine evaluation and management of disorders of salt and water balance in a large cohort of inpatients attending the national neurosciences referral centre in Dublin, Ireland, and compared this experience with findings from other studies. Patients: The study group included unselected neurosurgical patients admitted to our centre and requiring endocrine evaluation. Interventions: We conducted investigations to determine the underlying mechanistic basis for disorders of salt and water balance in neurosurgical patients and treatment to restore normal metabolism. Main Outcome Measures: Morbidity and mortality associated with deranged salt and water balance were measured. Results: The underlying pathophysiology of disordered water balance in neurosurgical patients is complex and varied and dictates the optimal therapeutic approach. Conclusions: A systematic and well-informed approach is needed to properly diagnose and manage disorders of salt and water balance in neurosurgical patients.
Item Type:
Article
Language:
en
ISSN:
1945-7197

Full metadata record

DC FieldValue Language
dc.contributor.authorHannon, Mark Jen_GB
dc.contributor.authorFinucane, Francis Men_GB
dc.contributor.authorSherlock, Marken_GB
dc.contributor.authorAgha, Amaren_GB
dc.contributor.authorThompson, Christopher Jen_GB
dc.date.accessioned2012-06-15T15:26:52Z-
dc.date.available2012-06-15T15:26:52Z-
dc.date.issued2012-05-
dc.identifier.citationDisorders of water homeostasis in neurosurgical patients. 2012, 97 (5):1423-33 J. Clin. Endocrinol. Metab.en_GB
dc.identifier.issn1945-7197-
dc.identifier.pmid22362821-
dc.identifier.doi10.1210/jc.2011-3201-
dc.identifier.urihttp://hdl.handle.net/10147/229192-
dc.description.abstractContext: Disorders of water balance are common in neurosurgical patients and usually manifest as hypo- or hypernatremia. They are most commonly seen after subarachnoid hemorrhage, traumatic brain injury, with intracranial tumors, and after pituitary surgery. Setting: We reviewed the experience of endocrine evaluation and management of disorders of salt and water balance in a large cohort of inpatients attending the national neurosciences referral centre in Dublin, Ireland, and compared this experience with findings from other studies. Patients: The study group included unselected neurosurgical patients admitted to our centre and requiring endocrine evaluation. Interventions: We conducted investigations to determine the underlying mechanistic basis for disorders of salt and water balance in neurosurgical patients and treatment to restore normal metabolism. Main Outcome Measures: Morbidity and mortality associated with deranged salt and water balance were measured. Results: The underlying pathophysiology of disordered water balance in neurosurgical patients is complex and varied and dictates the optimal therapeutic approach. Conclusions: A systematic and well-informed approach is needed to properly diagnose and manage disorders of salt and water balance in neurosurgical patients.en_GB
dc.language.isoenen
dc.rightsArchived with thanks to The Journal of clinical endocrinology and metabolismen_GB
dc.titleDisorders of water homeostasis in neurosurgical patients.en_GB
dc.typeArticleen
dc.contributor.departmentAcademic Department of Endocrinology, Beaumont Hospital, Dublin 9, Ireland. christhompson@beaumont.ie.en_GB
dc.identifier.journalThe Journal of clinical endocrinology and metabolismen_GB
dc.description.provinceLeinsteren

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